Early Detection of Low Cognitive Scores from Dual-task Performance Data Using a Spatio-temporal Graph Convolutional Neural Network

Detecting low cognitive scores at an early stage is important for delaying the progress of dementia. Investigations of early-stage detection have employed automatic assessment using dual-task (i.e., performing two different tasks simultaneously). However, current approaches to dual-task-based detection are based on either simple features or limited motion information, which degrades the detection accuracy. To address this problem, we proposed a framework that uses graph convolutional networks to extract spatio-temporal features from dual-task performance data. Moreover, to make the proposed method robust against data imbalance, we devised a loss function that directly optimizes the summation of the sensitivity and specificity of the detection of low cognitive scores (i.e., score≤ 23 or score≤ 27). Our evaluation is based on 171 subjects from 6 different senior citizens’ facilities. Our experimental results demonstrated that the proposed algorithm considerably outperforms the previous standard with respect to both the sensitivity and specificity of the detection of low cognitive scores.

[1]  Andrea Marchetti,et al.  Optimal RANSAC-Towards a Repeatable Algorithm for Finding the Optimal Set , 2013, J. WSCG.

[2]  David M. W. Powers,et al.  What the F-measure doesn't measure: Features, Flaws, Fallacies and Fixes , 2015, ArXiv.

[3]  Nitesh V. Chawla,et al.  SMOTE: Synthetic Minority Over-sampling Technique , 2002, J. Artif. Intell. Res..

[4]  O. Beauchet,et al.  Gait characteristics under different walking conditions: Association with the presence of cognitive impairment in community-dwelling older people , 2017, PloS one.

[5]  Hyunsuk Lee,et al.  Estimating Mini Mental State Examination Scores using Game-Specific Performance Values: A Preliminary Study , 2018, 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[6]  Kota Aoki,et al.  [Paper] Automatic Collection of Dual-task Human Behavior for Analysis of Cognitive Function , 2018 .

[7]  H. Pashler Dual-task interference in simple tasks: data and theory. , 1994, Psychological bulletin.

[8]  Lei Wang,et al.  A Comparative Review of Recent Kinect-Based Action Recognition Algorithms , 2019, IEEE Transactions on Image Processing.

[9]  N. Herrmann,et al.  Mini-Cog for the diagnosis of Alzheimer's disease dementia and other dementias within a primary care setting. , 2014, The Cochrane database of systematic reviews.

[10]  Dahua Lin,et al.  Spatial Temporal Graph Convolutional Networks for Skeleton-Based Action Recognition , 2018, AAAI.

[11]  Kai-Lung Hua,et al.  Pairwise Adjacency Matrix on Spatial Temporal Graph Convolution Network for Skeleton-Based Two-Person Interaction Recognition , 2020, 2020 IEEE International Conference on Image Processing (ICIP).

[12]  J. Cummings,et al.  The Montreal Cognitive Assessment, MoCA: A Brief Screening Tool For Mild Cognitive Impairment , 2005, Journal of the American Geriatrics Society.

[13]  G. Box Some Theorems on Quadratic Forms Applied in the Study of Analysis of Variance Problems, I. Effect of Inequality of Variance in the One-Way Classification , 1954 .

[14]  Bart Selman,et al.  Human Activity Detection from RGBD Images , 2011, Plan, Activity, and Intent Recognition.

[15]  P. Cochat,et al.  Et al , 2008, Archives de pediatrie : organe officiel de la Societe francaise de pediatrie.

[16]  Jia Wang,et al.  Action Recognition Based on Fusion Skeleton of Two Kinect Sensors , 2020, 2020 International Conference on Culture-oriented Science & Technology (ICCST).

[17]  Kota Aoki,et al.  Early Detection of Lower MMSE Scores in Elderly Based on Dual-Task Gait , 2019, IEEE Access.

[18]  Jian-Huang Lai,et al.  Jointly Learning Heterogeneous Features for RGB-D Activity Recognition , 2017, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[19]  Y. Yagi,et al.  Statistical Analysis of Dual-task Gait Characteristics for Cognitive Score Estimation , 2019, Scientific Reports.

[20]  E. Rovini,et al.  How Dominant Hand and Foot Dexterity May Reveal Dementia Onset: A Motor and Cognitive Dual-Task Study* , 2020, 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC).

[21]  Yang Song,et al.  Learning Fine-Grained Image Similarity with Deep Ranking , 2014, 2014 IEEE Conference on Computer Vision and Pattern Recognition.

[22]  Gang Wang,et al.  Multi-modal feature fusion for action recognition in RGB-D sequences , 2014, 2014 6th International Symposium on Communications, Control and Signal Processing (ISCCSP).

[23]  Yasushi Makihara,et al.  A video‐based gait disturbance assessment tool for diagnosing idiopathic normal pressure hydrocephalus , 2019 .

[24]  Yong Du,et al.  Hierarchical recurrent neural network for skeleton based action recognition , 2015, 2015 IEEE Conference on Computer Vision and Pattern Recognition (CVPR).

[25]  B. Taati,et al.  Assessment of Parkinsonian gait in older adults with dementia via human pose tracking in video data , 2020, Journal of NeuroEngineering and Rehabilitation.

[26]  H. B. Åhman,et al.  Dual-task tests discriminate between dementia, mild cognitive impairment, subjective cognitive impairment, and healthy controls – a cross-sectional cohort study , 2020, BMC Geriatrics.

[27]  Takumi Kobayashi,et al.  Spiral-Net with F1-Based Optimization for Image-Based Crack Detection , 2018, ACCV.

[28]  Yann LeCun,et al.  Dimensionality Reduction by Learning an Invariant Mapping , 2006, 2006 IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR'06).

[29]  Mert R. Sabuncu,et al.  Generalized Cross Entropy Loss for Training Deep Neural Networks with Noisy Labels , 2018, NeurIPS.

[30]  Lei Shi,et al.  Two-Stream Adaptive Graph Convolutional Networks for Skeleton-Based Action Recognition , 2018, 2019 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR).

[31]  Murtadha D. Hssayeni,et al.  Dual-Task Gait Assessment and Machine Learning for Early-detection of Cognitive Decline , 2020, 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC).

[32]  L. Guse,et al.  An examination of psychometric properties of the mini-mental state examination and the standardized mini-mental state examination: implications for clinical practice. , 2000, Applied nursing research : ANR.

[33]  Corinna Cortes,et al.  Support-Vector Networks , 1995, Machine Learning.

[34]  Gang Wang,et al.  Spatio-Temporal LSTM with Trust Gates for 3D Human Action Recognition , 2016, ECCV.

[35]  Andrew W. Fitzgibbon,et al.  Real-time human pose recognition in parts from single depth images , 2011, CVPR 2011.

[36]  Quincy M. Samus,et al.  Dementia prevention, intervention, and care , 2017, The Lancet.

[37]  Tie-Yan Liu,et al.  LightGBM: A Highly Efficient Gradient Boosting Decision Tree , 2017, NIPS.