Bioactivity refers to bio-inductive activity. The materials which induce such activity are bioactive materials. These materials induce a reaction from living tissue. Bioactive materials have a role in the promotion of the healing process, repair, maintaining the vitality of pulp, etc. The material should be sterile, bacteriostatic and bactericidal in nature. Bioactive materials are used in dentin remineralization, maintaining long-term restorations bonded with cement, and repairing intra-bony lesions. A biomaterial is a substance, external layer or assembly that interconnect with an organic system. Biognosisan analysis of, structure or uses of biologically generated materials, their mechanisms and processes for the formation of likely products by arti icial mechanisms that mimics natural structures. A biomaterial is a substance, external layer or assembly that interconnect with an organic system. These materials differ in their form and function and composition. Bioactive substances function works due to the inauguration of growth initiators and multiple cells. It aids in “growth, immigration, and distinction of odontoblast-like cells producing tissue matrix. Bioactive matrix form an outer layer of an apatite-like substance in association with inorganic phosphate solution. Bioactive materials like calcium hydroxide, mineral trioxide aggregate, biodentin, etc., are commonly used in routine practice. As these materials have multiple purposes, this review focuses to highlight newer materials in the category of bioactivity and their implications in dentistry particularly.
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