Bioavailability in humans of the flavanones hesperidin and narirutin after the ingestion of two doses of orange juice

[1]  F. Tomás-Barberán,et al.  In vitro availability of flavonoids and other phenolics in orange juice. , 2001, Journal of agricultural and food chemistry.

[2]  I. Merfort,et al.  Radical scavenger activity of three flavonoid metabolites studied by inhibition of chemiluminescence in human PMNs. , 1996, Planta medica.

[3]  J. R. Bell,et al.  Catechin is present as metabolites in human plasma after consumption of red wine. , 1999, The Journal of nutrition.

[4]  O. Texier,et al.  Quercetin is recovered in human plasma as conjugated derivatives which retain antioxidant properties , 1998, FEBS letters.

[5]  P. Hollman,et al.  Relative bioavailability of the antioxidant flavonoid quercetin from various foods in man , 1997, FEBS letters.

[6]  M. Reidenberg,et al.  A Method for Measuring Naringenin in Biological Fluids and Its Disposition from Grapefruit Juice by Man , 1998, Pharmacology.

[7]  J. Kumpulainen.  Intakes of flavonoids, phenolic acids and lignans in various populations , 2001 .

[8]  Takuji Tanaka,et al.  Chemopreventive effects of diosmin and hesperidin on N‐butyl‐N‐(4‐hydroxybutyl)nitrosamine‐induced urinary‐bladder carcinogenesis in male ICR mice , 1997, International journal of cancer.

[9]  R. Weintraub,et al.  Drug Interactions with Grapefruit Juice , 1997, Clinical pharmacokinetics.

[10]  K. Shimoi,et al.  Deglucuronidation of a flavonoid, luteolin monoglucuronide, during inflammation. , 2001, Drug metabolism and disposition: the biological fate of chemicals.

[11]  U. Fuhr,et al.  The fate of naringin in humans: A key to grapefruit juice‐drug interactions? , 1995, Clinical pharmacology and therapeutics.

[12]  L. Griffiths,et al.  Metabolism of flavonoid compounds in germ-free rats. , 1972, The Biochemical journal.

[13]  R. A. King,et al.  Plasma and urinary kinetics of the isoflavones daidzein and genistein after a single soy meal in humans. , 1998, The American journal of clinical nutrition.

[14]  C. Rice-Evans,et al.  Interactions of the flavonoid naringenin in the gastrointestinal tract and the influence of glycosylation. , 1999, Biochemical and biophysical research communications.

[15]  A. Aro,et al.  Plasma kinetics and urinary excretion of the flavanones naringenin and hesperetin in humans after ingestion of orange juice and grapefruit juice. , 2001, The Journal of nutrition.

[16]  C. Fraga,et al.  A dose-response effect from chocolate consumption on plasma epicatechin and oxidative damage. , 2000, The Journal of nutrition.

[17]  W. Mazur,et al.  Human Nutrition and Metabolisim Pharmacokinetics of Soybean Isoflavones in Plasma , Urine and Feces of Men after Ingestion of 60 g Baked Soybean Powder ( Kinako ) 1 , 2 , 1998 .

[18]  D Kromhout,et al.  Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands. , 1993, Nutrition and cancer.

[19]  F. DeEds,et al.  Metabolic and glucosuria studies on naringin and phloridzin. , 1958, The Journal of biological chemistry.

[20]  E. Offord,et al.  Plasma kinetics in man of epicatechin from black chocolate , 1999, European Journal of Clinical Nutrition.

[21]  C. Fraga,et al.  Epicatechin in human plasma: in vivo determination and effect of chocolate consumption on plasma oxidation status. , 2000, The Journal of nutrition.

[22]  A. Aro,et al.  Pharmacokinetics of quercetin from quercetin aglycone and rutin in healthy volunteers , 2000, European Journal of Clinical Pharmacology.

[23]  C. Rice-Evans,et al.  Structure-antioxidant activity relationships of flavonoids and phenolic acids. , 1996, Free radical biology & medicine.

[24]  R. Gebhardt,et al.  Comparison of antioxidative capacities and inhibitory effects on cholesterol biosynthesis of quercetin and potential metabolites. , 2002, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[25]  U. Justesen,et al.  Determination of plant polyphenols in Danish foodstuffs by HPLC-UV and LC-MS detection. , 1997, Cancer letters.

[26]  G. Jacobasch,et al.  Pharmacokinetics and Bioavailability of Quercetin Glycosides in Humans , 2001, Journal of clinical pharmacology.

[27]  R. Scheline,et al.  CRC handbook of mammalian metabolism of plant compounds , 1991 .

[28]  C. Shackleton,et al.  Hydrolysis of dietary flavonoid glycosides by strains of intestinal Bacteroides from humans. , 1987, The Biochemical journal.

[29]  W. Sly,et al.  Flavonoid glucuronides are substrates for human liver β‐glucuronidase , 2001 .

[30]  H. Li,et al.  Analysis of plasma and urinary tea polyphenols in human subjects. , 1995, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[31]  T. Osawa,et al.  Protective effects of lemon flavonoids on oxidative stress in diabetic rats , 1998, Lipids.

[32]  N. Pellegrini,et al.  DIETARY FLAVONOIDS AND OXIDATIVE STRESS , 1996 .

[33]  M. Clifford,et al.  Flavanones, chalcones and dihydrochalcones – nature, occurrence and dietary burden , 2000 .

[34]  T. Tsai,et al.  Determination of naringenin and its glucuronide conjugate in rat plasma and brain tissue by high-performance liquid chromatography. , 1998, Journal of chromatography. B, Biomedical sciences and applications.

[35]  Y. Kasuya,et al.  Mass spectrometric identification and high-performance liquid chromatographic determination of a flavonoid glycoside naringin in human urine. , 2000, Journal of agricultural and food chemistry.

[36]  E. M. Galati,et al.  Biological effects of hesperidin, a Citrus flavonoid. (note II): hypolipidemic activity on experimental hypercholesterolemia in rat. , 1995, Farmaco.

[37]  S. Laufer,et al.  Anti-inflammatory activity of myricetin-3-O-β-D-glucuronide and related compounds , 1998, Inflammation Research.

[38]  M. Lean,et al.  Absorption and excretion of conjugated flavonols, including quercetin-4'-O-beta-glucoside and isorhamnetin-4'-O-beta-glucoside by human volunteers after the consumption of onions. , 1998, Free radical research.

[39]  G. Soybir,et al.  Inhibitory effect of Hesperidin on tumour initiation and promotion in mouse skin , 1998, Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie.

[40]  U. Fuhr.  Drug Interactions with Grapefruit Juice , 1998, Drug safety.

[41]  May-Chen Kuo,et al.  Blood and urine levels of tea catechins after ingestion of different amounts of green tea by human volunteers. , 1998, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[42]  P. Murphy,et al.  Neither background diet nor type of soy food affects short-term isoflavone bioavailability in women. , 2000, The Journal of nutrition.

[43]  A. Scalbert,et al.  Bioavailability of the flavanone naringenin and its glycosides in rats. , 2000, American journal of physiology. Gastrointestinal and liver physiology.

[44]  G. Williamson,et al.  Conjugation position of quercetin glucuronides and effect on biological activity. , 2000, Free radical biology & medicine.

[45]  R. Rouseff,et al.  Flavanone absorption after naringin, hesperidin, and citrus administration , 1996, Clinical pharmacology and therapeutics.

[46]  P. Hollman,et al.  The sugar moiety is a major determinant of the absorption of dietary flavonoid glycosides in man. , 1999, Free radical research.

[47]  K. Kondo,et al.  Analysis of (-)-epigallocatechin gallate in human serum obtained after ingesting green tea. , 1996, Bioscience, biotechnology, and biochemistry.

[48]  L. Griffiths,et al.  The bilary excretion of flavanones in the rat. , 1979, Xenobiotica; the fate of foreign compounds in biological systems.

[49]  P. Murphy,et al.  Daidzein is a more bioavailable soymilk isoflavone than is genistein in adult women. , 1994, The Journal of nutrition.

[50]  A. Hara,et al.  Chemoprevention of azoxymethane-induced rat colon carcinogenesis by the naturally occurring flavonoids, diosmin and hesperidin. , 1997, Carcinogenesis.

[51]  O. Texier,et al.  Bioavailability of rutin and quercetin in rats , 1997, FEBS letters.

[52]  N. Borradaile,et al.  Regulation of HepG2 cell apolipoprotein B metabolism by the citrus flavanones hesperetin and naringenin , 1999, Lipids.

[53]  K. Son,et al.  Plasma and hepatic cholesterol and hepatic activities of 3-hydroxy-3-methyl-glutaryl-CoA reductase and acyl CoA: cholesterol transferase are lower in rats fed citrus peel extract or a mixture of citrus bioflavonoids. , 1999, The Journal of nutrition.

[54]  J. Terao,et al.  Identification of quercetin 3-O-beta-D-glucuronide as an antioxidative metabolite in rat plasma after oral administration of quercetin. , 2001, Free radical biology & medicine.