Visible Light Photocatalysis: Applications and New Disconnections in the Synthesis of Pharmaceutical Agents
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[1] A. A. Levy,et al. CCCCLII.—The rearrangement of hydroxy-sulphones. Part I , 1931 .
[2] H. Shizuka,et al. Photo-smiles rearrangements , 1970 .
[3] W. Speckamp,et al. A novel 1,4 arylradical rearrangement.☆ , 1972 .
[4] D. T. Sawyer,et al. On the chemical reactivity of superoxide ion , 1978 .
[5] W. Brown. Treatment of hypercholesterolaemia with fenofibrate: a review. , 1989, Current medical research and opinion.
[6] A. Wilks. Two putative protein-tyrosine kinases identified by application of the polymerase chain reaction. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[7] W. Motherwell,et al. A novel route to biaryls via intramolecular free radical ipso substitution reactions , 1991 .
[8] J. Cleveland,et al. Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[9] A. Rheingold,et al. Oxygen-atom transfer from nitrous oxide to a nickel metallacycle. Synthesis, structure, and reactions of [cyclic] (2,2'-bipyridine)Ni(OCH2CH2CH2CH2) , 1993 .
[10] T. Koenig,et al. A convenient method for preparing enantiomerically pure norfluoxetine, fluoxetine and tomoxetine , 1994 .
[11] John C. Mavropoulos,et al. Oxygen-atom transfer from nitrous oxide (NNO) to nickel alkyls. Syntheses and reactions of nickel(II) alkoxides , 1995 .
[12] D. Wong,et al. Prozac (fluoxetine, Lilly 110140), the first selective serotonin uptake inhibitor and an antidepressant drug: twenty years since its first publication. , 1995, Life sciences.
[13] J. Pinson,et al. Covalent Modification of Carbon Surfaces by Aryl Radicals Generated from the Electrochemical Reduction of Diazonium Salts , 1997 .
[14] G. Hillhouse,et al. Carbon−Oxygen Reductive-Elimination from Nickel(II) Oxametallacycles and Factors That Control Formation of Ether, Aldehyde, Alcohol, or Ester Products , 1997 .
[15] M. Hoekstra,et al. Chemical Development of CI-1008, an Enantiomerically Pure Anticonvulsant , 1997 .
[16] C. Alt,et al. Application of Heterogeneous Acid Catalysts to the Large-Scale Synthesis of 2- and 3-(p-Methoxyphenyl)-6-methoxybenzo[b]thiophenes , 1999 .
[17] A. Studer,et al. Radical aryl migration reactions , 2001 .
[18] R. Pohl,et al. Pregabalin: a new anxiolytic , 2003, Expert opinion on investigational drugs.
[19] Masaharu Nakamura,et al. Smiles-type free radical rearrangement of aromatic sulfonates and sulfonamides: syntheses of arylethanols and arylethylamines. , 2003, Organic & biomolecular chemistry.
[20] Martin Anker Nielsen,et al. Scale-Up and Safety Evaluation of a Sandmeyer Reaction , 2004 .
[21] T. Nemoto,et al. Efficient Synthesis of Chiral α‐ and β‐Hydroxy Amides: Application to the Synthesis of (R)‐Fluoxetine , 2004 .
[22] Mario Cazzola,et al. A gain-of-function mutation of JAK2 in myeloproliferative disorders. , 2005, The New England journal of medicine.
[23] J. Gauthier,et al. Practical and Efficient Route to (S)-γ-Fluoroleucine , 2005 .
[24] Paul N. Devine,et al. An Efficient Chemoenzymatic Approach to (S)-γ-Fluoroleucine Ethyl Ester , 2005 .
[25] I. Davies,et al. A Concise Synthesis of ( S )-?-Fluoroleucine Ethyl Ester , 2006 .
[26] M. Krische,et al. Enantioselective iridium-catalyzed carbonyl allylation from the alcohol or aldehyde oxidation level using allyl acetate as an allyl metal surrogate. , 2008, Journal of the American Chemical Society.
[27] C. Humblet,et al. Escape from flatland: increasing saturation as an approach to improving clinical success. , 2009, Journal of medicinal chemistry.
[28] K. Padiya,et al. Asymmetric Synthesis of (R)‐Fluoxetine: A Practical Approach Using Recyclable and in‐situ Generated Oxazaborolidine Catalyst , 2009 .
[29] Gregory A. Stephenson,et al. Practical Synthesis of Chiral 2-Morpholine: (4-Benzylmorpholin-2-(S)-yl)-(tetrahydropyran-4-yl)methanone Mesylate, a Useful Pharmaceutical Intermediate , 2009 .
[30] Christopher J. Welch,et al. MISER chromatography (multiple injections in a single experimental run): the chromatogram is the graph , 2010 .
[31] Gregory Hughes,et al. Development of an Improved Immobilized CAL-B for the Enzymatic Resolution of a Key Intermediate to Odanacatib , 2011 .
[32] D. MacMillan,et al. Trifluoromethylation of arenes and heteroarenes by means of photoredox catalysis , 2011, Nature.
[33] W. Xiao,et al. Visible-light-induced oxidation/[3+2] cycloaddition/oxidative aromatization sequence: a photocatalytic strategy to construct pyrrolo[2,1-a]isoquinolines. , 2011, Angewandte Chemie.
[34] Melanie S. Sanford,et al. Room-temperature C-H arylation: merger of Pd-catalyzed C-H functionalization and visible-light photocatalysis. , 2011, Journal of the American Chemical Society.
[35] Melanie S Sanford,et al. Combining Transition Metal Catalysis with Radical Chemistry: Dramatic Acceleration of Palladium-Catalyzed C-H Arylation with Diaryliodonium Salts. , 2012, Advanced synthesis & catalysis.
[36] S. Dadiboyena. Recent advances in the synthesis of raloxifene: a selective estrogen receptor modulator. , 2012, European journal of medicinal chemistry.
[37] C. Stephenson,et al. Shining light on photoredox catalysis: theory and synthetic applications. , 2012, The Journal of organic chemistry.
[38] Junichiro Yamaguchi,et al. C-H bond functionalization: emerging synthetic tools for natural products and pharmaceuticals. , 2012, Angewandte Chemie.
[39] K. P. Cole,et al. Development and a Practical Synthesis of the JAK2 Inhibitor LY2784544 , 2012 .
[40] Durga Prasad Hari,et al. Metal-free, visible-light-mediated direct C-H arylation of heteroarenes with aryl diazonium salts. , 2012, Journal of the American Chemical Society.
[41] Pixu Li,et al. Aerobic visible-light photoredox radical C-H functionalization: catalytic synthesis of 2-substituted benzothiazoles. , 2012, Organic letters.
[42] Durga Prasad Hari,et al. Visible light photocatalytic synthesis of benzothiophenes. , 2012, Organic letters.
[43] Kevin I Booker-Milburn,et al. Flow photochemistry: Old light through new windows , 2012, Beilstein journal of organic chemistry.
[44] Martin D. Johnson,et al. The continuous flow Barbier reaction: an improved environmental alternative to the Grignard reaction? , 2012 .
[45] N. Binkley,et al. Odanacatib in the treatment of postmenopausal women with low bone mineral density: Five years of continued therapy in a phase 2 study , 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[46] M. Reetz,et al. Biocatalysis in organic chemistry and biotechnology: past, present, and future. , 2013, Journal of the American Chemical Society.
[47] C. Nevado,et al. Copper-catalyzed one-pot trifluoromethylation/aryl migration/desulfonylation and C(sp2)-N bond formation of conjugated tosyl amides. , 2013, Journal of the American Chemical Society.
[48] B. Dardzinski,et al. Bone density, turnover, and estimated strength in postmenopausal women treated with odanacatib: a randomized trial. , 2013, The Journal of clinical endocrinology and metabolism.
[49] Qian Huang,et al. Discovery of MK‐8742: An HCV NS5A Inhibitor with Broad Genotype Activity , 2013, ChemMedChem.
[50] Frank Glorius,et al. Combining gold and photoredox catalysis: visible light-mediated oxy- and aminoarylation of alkenes. , 2013, Journal of the American Chemical Society.
[51] D. MacMillan,et al. Visible light photoredox catalysis with transition metal complexes: applications in organic synthesis. , 2013, Chemical reviews.
[52] Jinhua J. Song,et al. Development of a Safe and Economical Synthesis of Methyl 6-Chloro-5-(trifluoromethyl)nicotinate: Trifluoromethylation on Kilogram Scale , 2013 .
[53] F. Glorius,et al. Dual Photoredox and Gold Catalysis: Intermolecular Multicomponent Oxyarylation of Alkenes , 2014 .
[54] Corey R J Stephenson,et al. The Development of Visible-Light Photoredox Catalysis in Flow. , 2014, Israel journal of chemistry.
[55] Z. Zuo,et al. Carboxylic Acids as A Traceless Activation Group for Conjugate Additions: A Three-Step Synthesis of (±)-Pregabalin , 2014, Journal of the American Chemical Society.
[56] G. Molander,et al. Single-electron transmetalation in organoboron cross-coupling by photoredox/nickel dual catalysis , 2014, Science.
[57] Volker Hessel,et al. Photochemical transformations accelerated in continuous-flow reactors: basic concepts and applications. , 2014, Chemistry.
[58] K. P. Cole,et al. Photoredox Catalysis in a Complex Pharmaceutical Setting: Toward the Preparation of JAK2 Inhibitor LY2784544 , 2014, The Journal of organic chemistry.
[59] Matthew Burns,et al. Assembly-line synthesis of organic molecules with tailored shapes , 2014, Nature.
[60] F. Glorius,et al. An overview of N-heterocyclic carbenes , 2014, Nature.
[61] Ying He,et al. Dual Visible Light Photoredox and Gold-Catalyzed Arylative Ring Expansion , 2014, Journal of the American Chemical Society.
[62] David A. Nicewicz,et al. Recent Applications of Organic Dyes as Photoredox Catalysts in Organic Synthesis , 2014 .
[63] T. Jamison,et al. Recent advances in homogeneous nickel catalysis , 2014, Nature.
[64] Z. Zuo,et al. Decarboxylative Arylation of α-Amino Acids via Photoredox Catalysis: A One-Step Conversion of Biomass to Drug Pharmacophore , 2014, Journal of the American Chemical Society.
[65] Shane W. Krska,et al. Late-stage functionalization of biologically active heterocycles through photoredox catalysis. , 2014, Angewandte Chemie.
[66] David C. Fabry,et al. Synthesis of indoles using visible light: photoredox catalysis for palladium-catalyzed C-H activation. , 2014, Angewandte Chemie.
[67] Melodie Christensen,et al. Enantioselective synthesis of an HCV NS5a antagonist. , 2014, Organic letters.
[68] Guido Koch,et al. Batch versus flow photochemistry: a revealing comparison of yield and productivity. , 2014, Chemistry.
[69] M. Reibarkh,et al. Asymmetric synthesis of cyclic indole aminals via 1,3-stereoinduction. , 2014, The Journal of organic chemistry.
[70] J. W. Wong,et al. Evaluation of Several Routes to Advanced Pregabalin Intermediates: Synthesis and Enantioselective Enzymatic Reduction Using Ene-Reductases , 2014 .
[71] jin-quan yu,et al. Bypassing the Limitations of Directed C–H Functionalizations of Heterocycles , 2014, Nature.
[72] M. Akita,et al. Hydroaminomethylation of Olefins with Aminomethyltrifluoroborate by Photoredox Catalysis , 2014 .
[73] D. MacMillan,et al. Merging Photoredox and Nickel Catalysis: The Direct Synthesis of Ketones by the Decarboxylative Arylation of α-Oxo Acids. , 2015, Angewandte Chemie.
[74] J. Reymond. The chemical space project. , 2015, Accounts of chemical research.
[75] E. Regalado,et al. Development of a Direct Photocatalytic C-H Fluorination for the Preparative Synthesis of Odanacatib. , 2015, Organic letters.
[76] Thomas E. La Cruz,et al. Practical olefin hydroamination with nitroarenes , 2015, Science.
[77] D. MacMillan,et al. Switching on Elusive Organometallic Mechanisms with Photoredox Catalysis , 2015, Nature.
[78] J. Wepsiec,et al. Synthesis of an ORL-1 Receptor Antagonist via a Radical Bromination and Deoxyfluorination to Afford a gem-Difluorospirocycle , 2015 .
[79] B. Aquila,et al. Effects of Molecular Oxygen, Solvent, and Light on Iridium-Photoredox/Nickel Dual-Catalyzed Cross-Coupling Reactions. , 2015, The Journal of organic chemistry.
[80] D. Stephan. Frustrated Lewis Pairs. , 2015, Journal of the American Chemical Society.
[81] C. Le,et al. Fragment Couplings via CO2 Extrusion-Recombination: Expansion of a Classic Bond-Forming Strategy via Metallaphotoredox. , 2015, Journal of the American Chemical Society.
[82] T. Chatterjee,et al. Synthesis of Carbazoles by a Merged Visible Light Photoredox and Palladium-Catalyzed Process , 2015 .
[83] Mauro F. A. Adamo,et al. Development and Scale-up of an Organocatalytic Enantioselective Process to Manufacture (S)-Pregabalin , 2015 .
[84] T. Ritter,et al. Late-stage fluorination: fancy novelty or useful tool? , 2015, Angewandte Chemie.
[85] N. Oger,et al. Handling diazonium salts in flow for organic and material chemistry , 2015 .
[86] Lei Wang,et al. Merging Photoredox with Palladium Catalysis: Decarboxylative ortho-Acylation of Acetanilides with α-Oxocarboxylic Acids under Mild Reaction Conditions. , 2015, Organic letters.
[87] David A. Nicewicz,et al. Site-selective arene C-H amination via photoredox catalysis , 2015, Science.
[88] Y. Tu,et al. Radical aryl migration reactions and synthetic applications. , 2015, Chemical Society reviews.
[89] Megan A. Cismesia,et al. Characterizing chain processes in visible light photoredox catalysis , 2015, Chemical Science.
[90] Corey R J Stephenson,et al. A Visible-Light-Mediated Radical Smiles Rearrangement and its Application to the Synthesis of a Difluoro-Substituted Spirocyclic ORL-1 Antagonist. , 2015, Angewandte Chemie.
[91] T. Jamison,et al. Highly Regioselective Indoline Synthesis under Nickel/Photoredox Dual Catalysis. , 2015, Journal of the American Chemical Society.
[92] F. Palacios,et al. Carbon trifluoromethylation reactions of hydrocarbon derivatives and heteroarenes. , 2015, Chemical reviews.
[93] K. P. Cole,et al. A scalable and operationally simple radical trifluoromethylation , 2015, Nature Communications.
[94] M. Kozlowski,et al. Nickel-Catalyzed Cross-Coupling of Photoredox-Generated Radicals: Uncovering a General Manifold for Stereoconvergence in Nickel-Catalyzed Cross-Couplings , 2015, Journal of the American Chemical Society.
[95] K. Goossen,et al. Late transition metal-catalyzed hydroamination and hydroamidation. , 2015, Chemical reviews.
[96] J. Li. C-H Bond Activation in Organic Synthesis , 2015 .
[97] H. Alper,et al. Redox-neutral α-allylation of amines by combining palladium catalysis and visible-light photoredox catalysis. , 2015, Angewandte Chemie.
[98] P. Champagne,et al. Monofluorination of Organic Compounds: 10 Years of Innovation. , 2015, Chemical reviews.
[99] Jonas Boström,et al. Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone? , 2016, Journal of medicinal chemistry.
[100] K. P. Cole,et al. Preparative Scale Demonstration and Mechanistic Investigation of a Visible Light-Mediated Radical Smiles Rearrangement , 2016 .
[101] Scott J. Miller,et al. Site-Selective Reactions with Peptide-Based Catalysts. , 2016, Topics in current chemistry.
[102] F. Glorius,et al. Dual gold/photoredox-catalyzed C(sp)–H arylation of terminal alkynes with diazonium salts† †Electronic supplementary information (ESI) available: General experimental details, full optimization table, kinetic profile, experimental procedures and characterization data of products, copies of NMR spect , 2015, Chemical science.
[103] Ian W. Davies,et al. Discovery and mechanistic study of a photocatalytic indoline dehydrogenation for the synthesis of elbasvir† †Electronic supplementary information (ESI) available: Detailed experimental procedures and characterization data for all new compounds. See DOI: 10.1039/c5sc03350k , 2015, Chemical science.
[104] B. Aquila,et al. Photoredox Mediated Nickel Catalyzed Cross-Coupling of Thiols With Aryl and Heteroaryl Iodides via Thiyl Radicals. , 2016, Journal of the American Chemical Society.
[105] Tim Cernak,et al. The medicinal chemist's toolbox for late stage functionalization of drug-like molecules. , 2016, Chemical Society reviews.
[106] A. Studer,et al. Catalysis of Radical Reactions: A Radical Chemistry Perspective. , 2016, Angewandte Chemie.