Itraconazole pulse: an overview of current use.

Traditionally, fungal infections of the fingernails and toenails have been difficult to treat. Itraconazole is an orally administered triazole antifungal agent with a wide spectrum of activity against dermatophytes, yeasts and some moulds. Pulse therapy with itraconazole is an effective new treatment which offers the shortest treatment course with the least total number of treatment days and lowest total dose.