Comparison of Three Different Doses of Ketamine-Propofol Combination In Short Surgical Procedures as Sedative and Analgesic. -

Background: Menstrual cycle is a physiological process that occurs in women. Changes in the levels of female sex hormones during menstrual cycle are known to affect the coagulation cascade by producing parallel changes in the prothrombotic tendency and the fibrinolytic activity of healthy women Objective-Evaluation of haematological factors in various phases of menstrual cycle. Materials and Methods: The study was conducted on 20 female subjects in the age group of 18-22 years over a period of 1 year. Three venous samples were taken during single menstrual cycle in menstrual, proliferative, and secretory phases in each subject and were followed up. The various parameters noted were absolute platelet count, prothrombin time and whole blood clotting time. Results: Comparison of absolute Platelet count and Prothrombin time during menstrual versus proliferative phases showed statistically significant difference (p

[1]  A. Küçük,et al.  Comparison of Dexmedetomidine Versus Ketamine-Propofol Combination for Sedation in Cataract Surgery. , 2015, Turkish journal of anaesthesiology and reanimation.

[2]  K. M. Elsayed,et al.  A clinical comparison of ketofol (ketamine and propofol admixture) versus propofol as an induction agent on quality of laryngeal mask airway insertion and hemodynamic stability in children , 2013, Anesthesia, essays and researches.

[3]  Sabyasachi Das,et al.  Intravenous infusion of ketamine-propofol can be an alternative to intravenous infusion of fentanyl-propofol for deep sedation and analgesia in paediatric patients undergoing emergency short surgical procedures , 2012, Indian journal of anaesthesia.

[4]  A. Esmaoğlu,et al.  Propofol–ketamine vs propofol–fentanyl combinations for deep sedation and analgesia in pediatric patients undergoing burn dressing changes a , 2007, Paediatric anaesthesia.

[5]  A. Esmaoğlu,et al.  Propofol‐ketamine vs propofol‐fentanyl for sedation during pediatric upper gastrointestinal endoscopy , 2007, Paediatric anaesthesia.

[6]  G. Andolfatto,et al.  A prospective evaluation of "ketofol" (ketamine/propofol combination) for procedural sedation and analgesia in the emergency department. , 2007, Annals of emergency medicine.

[7]  V. Shah,et al.  Comparison of admixtures of propofol-thiopentone, propofol-ketamine and propofol in ambulatory surgery , 2005 .

[8]  M. Imamura,et al.  [Anesthetic management by total intravenous anesthesia with propofol, pentazocine and ketamine]. , 2005, Masui. The Japanese journal of anesthesiology.

[9]  H. Erbay,et al.  Effects of low dose ketamine before induction on propofol anesthesia for pediatric magnetic resonance imaging , 2004, Paediatric anaesthesia.

[10]  K. Sano,et al.  Effects of a propofol--ketamine admixture in human volunteers. , 2003, Pacific health dialog.

[11]  R. F. Mortero,et al.  The Effects of Small-Dose Ketamine on Propofol Sedation: Respiration, Postoperative Mood, Perception, Cognition, and Pain , 2001, Anesthesia and analgesia.

[12]  M. Ozaki,et al.  Intravenous ketamine attenuates arterial pressure changes during the induction of anaesthesia with propofol , 2001, European journal of anaesthesiology.

[13]  Seiya Nakamura,et al.  Appropriate method of administration of propofol, fentanyl, and ketamine for patient-controlled sedation and analgesia during extracorporeal shock-wave lithotripsy , 2000, Journal of Anesthesia.

[14]  A. Ivankovich,et al.  The Use of a Ketamine-Propofol Combination During Monitored Anesthesia Care , 2000, Anesthesia and analgesia.

[15]  C. Swinhoe,et al.  Target controlled infusion of ketamine as analgesia for TIVA with propofol , 1999, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

[16]  B. Friedberg.  Facial laser resurfacing with the propofol-ketamine technique: room air, spontaneous ventilation (RASV) anesthesia. , 1999, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[17]  F. Parramon,et al.  [Comparative study of 3 techniques for total intravenous anesthesia: midazolam-ketamine, propofol-ketamine, and propofol-fentanyl]. , 1999, Revista espanola de anestesiologia y reanimacion.

[18]  J. Plummer,et al.  Additive Interactions between Propofol and Ketamine When Used for Anesthesia Induction in Female Patients , 1995, Anesthesiology.

[19]  H. Schwilden,et al.  [Optimal dosage strategies in total intravenous anesthesia using propofol and ketamine]. , 1991, Der Anaesthesist.

[20]  D. Mackie,et al.  Ketamine as analgesic for total intravenous anaesthesia with propofol , 1991, Anaesthesia.

[21]  S. Vesconi,et al.  [Propofol-ketamine vs propofol-fentanyl in short gynecologic surgery]. , 1990, Minerva anestesiologica.