Functions and regulation of RNA editing by ADAR deaminases.
暂无分享,去创建一个
[1] S. Maas,et al. Identification of a selective nuclear import signal in adenosine deaminases acting on RNA , 2009, Nucleic acids research.
[2] Wenjing Zhang,et al. Origins and evolution of ADAR‐mediated RNA editing , 2009, IUBMB life.
[3] J. Rosenthal,et al. An extra double-stranded RNA binding domain confers high activity to a squid RNA editing enzyme. , 2009, RNA.
[4] Mats Ensterö,et al. Large-scale mRNA sequencing determines global regulation of RNA editing during brain development. , 2009, Genome research.
[5] G. Church,et al. Genome-Wide Identification of Human RNA Editing Sites by Parallel DNA Capturing and Sequencing , 2009, Science.
[6] J. Kawai,et al. The regulated retrotransposon transcriptome of mammalian cells , 2009, Nature Genetics.
[7] S. Maas,et al. Novel Exon of Mammalian ADAR2 Extends Open Reading Frame , 2009, PloS one.
[8] M. Jantsch,et al. RNA-Regulated Interaction of Transportin-1 and Exportin-5 with the Double-Stranded RNA-Binding Domain Regulates Nucleocytoplasmic Shuttling of ADAR1 , 2009, Molecular and Cellular Biology.
[9] S. Orkin,et al. ADAR1 is essential for maintenance of hematopoiesis and suppression of interferon signaling , 2008, Nature Immunology.
[10] K. Nishikura,et al. Dysregulated Editing of Serotonin 2C Receptor mRNAs Results in Energy Dissipation and Loss of Fat Mass , 2008, The Journal of Neuroscience.
[11] J. Brosius,et al. Beyond DNA: RNA editing and steps toward Alu exonization in primates. , 2008, Journal of molecular biology.
[12] S. Maas,et al. Screening of human SNP database identifies recoding sites of A-to-I RNA editing. , 2008, RNA.
[13] T. Ishihara,et al. ADBP-1 Regulates an ADAR RNA-Editing Enzyme to Antagonize RNA-Interference-Mediated Gene Silencing in Caenorhabditis elegans , 2008, Genetics.
[14] B. Bass,et al. C. elegans and H. sapiens mRNAs with edited 3' UTRs are present on polysomes. , 2008, RNA.
[15] G. Ruvkun,et al. Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7 , 2008, Nature.
[16] G. Carmichael,et al. On the mechanism of induction of heterochromatin by the RNA-binding protein vigilin. , 2008, RNA.
[17] Molly Megraw,et al. Frequency and fate of microRNA editing in human brain , 2008, Nucleic acids research.
[18] R. Reenan,et al. RNA editing in regulating gene expression in the brain. , 2008, Biochimica et biophysica acta.
[19] G. Carmichael,et al. Alu element‐mediated gene silencing , 2008, The EMBO journal.
[20] R. Emeson,et al. Developmental Modulation of GABAA Receptor Function by RNA Editing , 2008, The Journal of Neuroscience.
[21] Taishin Kin,et al. Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells , 2008, Nature.
[22] N. Perrimon,et al. An endogenous small interfering RNA pathway in Drosophila , 2008, Nature.
[23] D. Bartel,et al. The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs , 2008, Nature.
[24] Y. Sakaki,et al. Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes , 2008, Nature.
[25] Oliver H. Tam,et al. Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes , 2008, Nature.
[26] Hideo Negishi,et al. Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules , 2008, Proceedings of the National Academy of Sciences.
[27] R. Sperling,et al. The editing enzyme ADAR1 and the mRNA surveillance protein hUpf1 interact in the cell nucleus , 2008, Proceedings of the National Academy of Sciences.
[28] M. O’Connell,et al. Down-regulation of RNA Editing in Pediatric Astrocytomas , 2008, Journal of Biological Chemistry.
[29] A. Scadden. Inosine-Containing dsRNA Binds a Stress-Granule-like Complex and Downregulates Gene Expression In trans , 2007, Molecular cell.
[30] T. Mikkelsen,et al. Altered adenosine-to-inosine RNA editing in human cancer. , 2007, Genome research.
[31] J. Gore,et al. Hyperphagia-mediated Obesity in Transgenic Mice Misexpressing the RNA-editing Enzyme ADAR2* , 2007, Journal of Biological Chemistry.
[32] Yukio Kawahara,et al. RNA editing of the microRNA‐151 precursor blocks cleavage by the Dicer–TRBP complex , 2007, EMBO reports.
[33] M. Ohman,et al. The C-terminal domain of RNA Pol II helps ensure that editing precedes splicing of the GluR-B transcript. , 2007, RNA.
[34] K. Nishikura,et al. RNA Binding-independent Dimerization of Adenosine Deaminases Acting on RNA and Dominant Negative Effects of Nonfunctional Subunits on Dimer Functions* , 2007, Journal of Biological Chemistry.
[35] David Haussler,et al. Editing modifies the GABAA receptor subunit α3 , 2007 .
[36] L. Landweber,et al. Hypothesis: RNA editing of microRNA target sites in humans? , 2007, RNA.
[37] A. Hatzigeorgiou,et al. Redirection of Silencing Targets by Adenosine-to-Inosine Editing of miRNAs , 2007, Science.
[38] Eli Eisenberg,et al. RNA-editing-mediated exon evolution , 2007, Genome Biology.
[39] K. Nishikura,et al. Editor meets silencer: crosstalk between RNA editing and RNA interference , 2006, Nature Reviews Molecular Cell Biology.
[40] Eli Eisenberg,et al. RNA editing level in the mouse is determined by the genomic repeat repertoire. , 2006, RNA.
[41] D. Srivastava. Making or Breaking the Heart: From Lineage Determination to Morphogenesis , 2006, Cell.
[42] S. Celniker,et al. RNA editing in Drosophila melanogaster: New targets and functional consequences. , 2006, RNA.
[43] F. Nielsen,et al. Dimerization of ADAR2 is mediated by the double-stranded RNA binding domain. , 2006, RNA.
[44] A. MacMillan,et al. FRET Analysis of in Vivo Dimerization by RNA-editing Enzymes* , 2006, Journal of Biological Chemistry.
[45] P. L. Peng,et al. ADAR2-Dependent RNA Editing of AMPA Receptor Subunit GluR2 Determines Vulnerability of Neurons in Forebrain Ischemia , 2006, Neuron.
[46] F. Allain,et al. Structure and specific RNA binding of ADAR2 double-stranded RNA binding motifs. , 2006, Structure.
[47] R. Emeson,et al. Altered RNA Editing in Mice Lacking ADAR2 Autoregulation , 2006, Molecular and Cellular Biology.
[48] Yukio Kawahara,et al. A-to-I RNA Editing and Human Disease , 2006, RNA biology.
[49] P. Seeburg,et al. Modulation of microRNA processing and expression through RNA editing by ADAR deaminases , 2006, Nature Structural &Molecular Biology.
[50] Anton J. Enright,et al. RNA editing of human microRNAs , 2006, Genome Biology.
[51] M. Carmo-Fonseca,et al. SUMO-1 modification alters ADAR1 editing activity. , 2005, Molecular biology of the cell.
[52] Phillip D Zamore,et al. microPrimer: the biogenesis and function of microRNA , 2005, Development.
[53] Michael Q. Zhang,et al. Regulating Gene Expression through RNA Nuclear Retention , 2005, Cell.
[54] Weida Huang,et al. High doses of siRNAs induce eri-1 and adar-1 gene expression and reduce the efficiency of RNA interference in the mouse. , 2005, The Biochemical journal.
[55] B. Bass,et al. Inositol Hexakisphosphate Is Bound in the ADAR2 Core and Required for RNA Editing , 2005, Science.
[56] P. Kao,et al. ADAR1 Interacts with NF90 through Double-Stranded RNA and Regulates NF90-Mediated Gene Expression Independently of RNA Editing , 2005, Molecular and Cellular Biology.
[57] E. Levanon,et al. Identification of RNA editing sites in the SNP database , 2005, Nucleic acids research.
[58] R. Reenan,et al. Tuning of RNA editing by ADAR is required in Drosophila , 2005, The EMBO journal.
[59] Daniel R. Clutterbuck,et al. A bioinformatic screen for novel A-I RNA editing sites reveals recoding editing in BC10 , 2005, Bioinform..
[60] A. Scadden. The RISC subunit Tudor-SN binds to hyper-edited double-stranded RNA and promotes its cleavage , 2005, Nature Structural &Molecular Biology.
[61] M. Puig,et al. New Antiviral Pathway That Mediates Hepatitis C Virus Replicon Interferon Sensitivity through ADAR1 , 2005, Journal of Virology.
[62] V. Kim. MicroRNA biogenesis: coordinated cropping and dicing , 2005, Nature Reviews Molecular Cell Biology.
[63] R. Reenan. Molecular determinants and guided evolution of species-specific RNA editing , 2005, Nature.
[64] Erez Y. Levanon,et al. Evolutionarily conserved human targets of adenosine to inosine RNA editing , 2005, Nucleic acids research.
[65] Zuo Zhang,et al. Vigilins Bind to Promiscuously A-to-I-Edited RNAs and Are Involved in the Formation of Heterochromatin , 2005, Current Biology.
[66] J. Castle,et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs , 2005, Nature.
[67] C. Sander,et al. Identification of microRNAs of the herpesvirus family , 2005, Nature Methods.
[68] K. Nishikura,et al. ADAR1 RNA Deaminase Limits Short Interfering RNA Efficacy in Mammalian Cells* , 2005, Journal of Biological Chemistry.
[69] R. Sorek,et al. Is abundant A-to-I RNA editing primate-specific? , 2004, Trends in genetics : TIG.
[70] K. Nishikura,et al. ADAR gene family and A-to-I RNA editing: diverse roles in posttranscriptional gene regulation. , 2005, Progress in nucleic acid research and molecular biology.
[71] C. Schmauss. Regulation of serotonin 2C receptor pre-mRNA editing by serotonin. , 2005, International review of neurobiology.
[72] Richard Wooster,et al. A survey of RNA editing in human brain. , 2004, Genome research.
[73] Alexander Rich,et al. Widespread A-to-I RNA Editing of Alu-Containing mRNAs in the Human Transcriptome , 2004, PLoS biology.
[74] T. Tuschl,et al. Mechanisms of gene silencing by double-stranded RNA , 2004, Nature.
[75] Joshua J C Rosenthal,et al. Control of human potassium channel inactivation by editing of a small mRNA hairpin , 2004, Nature Structural &Molecular Biology.
[76] T. Matise,et al. Widespread RNA editing of embedded alu elements in the human transcriptome. , 2004, Genome research.
[77] Henry Mirsky,et al. RNA editing of a miRNA precursor. , 2004, RNA.
[78] Zipora Y. Fligelman,et al. Systematic identification of abundant A-to-I editing sites in the human transcriptome , 2004, Nature Biotechnology.
[79] Ichiro Kanazawa,et al. Glutamate receptors: RNA editing and death of motor neurons , 2004, Nature.
[80] M. Weiss,et al. Stress-induced Apoptosis Associated with Null Mutation of ADAR1 RNA Editing Deaminase Gene* , 2004, Journal of Biological Chemistry.
[81] P. Seeburg,et al. Liver Disintegration in the Mouse Embryo Caused by Deficiency in the RNA-editing Enzyme ADAR1* , 2004, Journal of Biological Chemistry.
[82] D. Bartel. MicroRNAs Genomics, Biogenesis, Mechanism, and Function , 2004, Cell.
[83] Brenda L Bass,et al. Mutations in RNAi Rescue Aberrant Chemotaxis of ADAR Mutants , 2003, Science.
[84] K. Wells,et al. Modulation of RNA editing by functional nucleolar sequestration of ADAR2 , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[85] Tamio Suzuki,et al. Mutations of the RNA-specific adenosine deaminase gene (DSRAD) are involved in dyschromatosis symmetrica hereditaria. , 2003, American journal of human genetics.
[86] R. Reenan,et al. Nervous System Targets of RNA Editing Identified by Comparative Genomics , 2003, Science.
[87] M. O’Connell,et al. An ADAR that edits transcripts encoding ion channel subunits functions as a dimer , 2003, The EMBO journal.
[88] J. Vaughn,et al. RNA editing and regulation of Drosophila 4f-rnp expression by sas-10 antisense readthrough mRNA transcripts. , 2003, RNA.
[89] P. Seeburg,et al. Regulation of ion channel/neurotransmitter receptor function by RNA editing , 2003, Current Opinion in Neurobiology.
[90] John M. Murray,et al. Requirement of Dimerization for RNA Editing Activity of Adenosine Deaminases Acting on RNA* , 2003, The Journal of Biological Chemistry.
[91] Y. Nie,et al. Widespread inosine‐containing mRNA in lymphocytes regulated by ADAR1 in response to inflammation , 2003, Immunology.
[92] M. Carmo-Fonseca,et al. Dynamic association of RNA-editing enzymes with the nucleolus , 2003, Journal of Cell Science.
[93] Gregor Eichele,et al. Human chromosome 21 gene expression atlas in the mouse , 2002, Nature.
[94] B. Bass,et al. RNA editing by ADARs is important for normal behavior in Caenorhabditis elegans , 2002, The EMBO journal.
[95] B. Bass,et al. The role of RNA editing by ADARs in RNAi. , 2002, Molecular cell.
[96] Y. Yoshida,et al. Blockage of Ca2+-permeable AMPA receptors suppresses migration and induces apoptosis in human glioblastoma cells , 2002, Nature Medicine.
[97] W. Keller,et al. tadA, an essential tRNA‐specific adenosine deaminase from Escherichia coli , 2002, The EMBO journal.
[98] Francisco Bezanilla,et al. Extensive Editing of mRNAs for the Squid Delayed Rectifier K+ Channel Regulates Subunit Tetramerization , 2002, Neuron.
[99] Victoria Arango,et al. Altered Editing of Serotonin 2C Receptor Pre-mRNA in the Prefrontal Cortex of Depressed Suicide Victims , 2002, Neuron.
[100] T. Maniatis,et al. An extensive network of coupling among gene expression machines , 2002, Nature.
[101] Brenda L Bass,et al. RNA editing by adenosine deaminases that act on RNA. , 2002, Annual review of biochemistry.
[102] Christopher W. J. Smith,et al. RNAi is antagonized by A→I hyper‐editing , 2001, EMBO reports.
[103] M Schrey,et al. Underediting of glutamate receptor GluR-B mRNA in malignant gliomas , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[104] J. Kjems,et al. CRM1 Mediates the Export of ADAR1 through a Nuclear Export Signal within the Z-DNA Binding Domain , 2001, Molecular and Cellular Biology.
[105] M. O’Connell,et al. The many roles of an RNA editor , 2001, Nature Reviews Genetics.
[106] Zuo Zhang,et al. The Fate of dsRNA in the Nucleus A p54nrb-Containing Complex Mediates the Nuclear Retention of Promiscuously A-to-I Edited RNAs , 2001, Cell.
[107] M. Jantsch,et al. The human but not the Xenopus RNA-editing enzyme ADAR1 has an atypical nuclear localization signal and displays the characteristics of a shuttling protein. , 2001, Molecular biology of the cell.
[108] W. Keller,et al. RNA editing by base deamination: more enzymes, more targets, new mysteries. , 2001, Trends in biochemical sciences.
[109] R. Sperling,et al. RNA editing activity is associated with splicing factors in lnRNP particles: The nuclear pre-mRNA processing machinery , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[110] Colleen M Niswender,et al. RNA Editing of the Human Serotonin 5-HT2C Receptor: Alterations in Suicide and Implications for Serotonergic Pharmacotherapy , 2001, Neuropsychopharmacology.
[111] David Baltimore,et al. Our genome unveiled , 2001, Nature.
[112] R. Reenan. The RNA world meets behavior: A-->I pre-mRNA editing in animals. , 2001, Trends in genetics : TIG.
[113] K. Nishikura,et al. Requirement of the RNA editing deaminase ADAR1 gene for embryonic erythropoiesis. , 2000, Science.
[114] C. Samuel,et al. Human RNA-specific adenosine deaminase (ADAR1) gene specifies transcripts that initiate from a constitutively active alternative promoter. , 2000, Gene.
[115] R. Reenan,et al. A-to-I Pre-mRNA Editing in Drosophila Is Primarily Involved in Adult Nervous System Function and Integrity , 2000, Cell.
[116] D. Feldmeyer,et al. Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2 , 2000, Nature.
[117] R. Reenan,et al. dADAR, a Drosophila double-stranded RNA-specific adenosine deaminase is highly developmentally regulated and is itself a target for RNA editing. , 2000, RNA.
[118] K. Gardiner,et al. Comparative analysis of the RED1 and RED2 A-to-I RNA editing genes from mammals, pufferfish and zebrafish. , 2000, Gene.
[119] K. Gardiner,et al. Comparative analysis of the DRADA A-to-I RNA editing gene from mammals, pufferfish and zebrafish. , 2000, Gene.
[120] K. Nishikura,et al. A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single- and double-stranded RNA binding domains. , 2000, RNA.
[121] B. Bass. Double-Stranded RNA as a Template for Gene Silencing , 2000, Cell.
[122] P. Sharp,et al. RNAi Double-Stranded RNA Directs the ATP-Dependent Cleavage of mRNA at 21 to 23 Nucleotide Intervals , 2000, Cell.
[123] K. Nishikura,et al. Altered G Protein‐Coupling Functions of RNA Editing Isoform and Splicing Variant Serotonin2C Receptors , 2000, Journal of neurochemistry.
[124] R. Reenan,et al. The mlenapts RNA Helicase Mutation in Drosophila Results in a Splicing Catastrophe of the para Na+ Channel Transcript in a Region of RNA Editing , 2000, Neuron.
[125] R. Emeson,et al. Functions and mechanisms of RNA editing. , 2000, Annual review of genetics.
[126] K. A. Lehmann,et al. The importance of internal loops within RNA substrates of ADAR1. , 1999, Journal of molecular biology.
[127] T. Dawson,et al. Regulation of alternative splicing by RNA editing , 1999, Nature.
[128] Colleen M. Niswender,et al. RNA Editing of the Human Serotonin 5-Hydroxytryptamine 2C Receptor Silences Constitutive Activity* , 1999, The Journal of Biological Chemistry.
[129] S C Schultz,et al. Molecular basis of double‐stranded RNA‐protein interactions: structure of a dsRNA‐binding domain complexed with dsRNA , 1998, The EMBO journal.
[130] J. C. Hall,et al. RNA editing in the Drosophila DMCA1A calcium-channel alpha 1 subunit transcript. , 1998, Journal of neurogenetics.
[131] B. Bass,et al. Inosine exists in mRNA at tissue‐specific levels and is most abundant in brain mRNA , 1998, The EMBO journal.
[132] I. Mian,et al. A Z-DNA binding domain present in the human editing enzyme, double-stranded RNA adenosine deaminase. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[133] R. Emeson,et al. Regulation of serotonin-2C receptor G-protein coupling by RNA editing , 1997, Nature.
[134] W. Keller,et al. Two forms of human double-stranded RNA-specific editase 1 (hRED1) generated by the insertion of an Alu cassette. , 1997, RNA.
[135] K. Nishikura,et al. Editing of glutamate receptor B subunit ion channel RNAs by four alternatively spliced DRADA2 double-stranded RNA adenosine deaminases , 1997, Molecular and cellular biology.
[136] P. Seeburg,et al. RED2, a Brain-specific Member of the RNA-specific Adenosine Deaminase Family* , 1996, The Journal of Biological Chemistry.
[137] Jychian Chen,et al. Molecular Analysis of cDNA Molecules Encoding Glutamate Receptor Subunits, fGluR1α and fGluR1β, of Oreochromis sp. , 1996 .
[138] P. Seeburg,et al. Structural Requirements for RNA Editing in Glutamate Receptor Pre-mRNAs by Recombinant Double-stranded RNA Adenosine Deaminase (*) , 1996, The Journal of Biological Chemistry.
[139] Brenda L. Bass,et al. RNA editing of hepatitis delta virus antigenome by dsRNA-adenosine deaminase , 1996, Nature.
[140] P. Seeburg,et al. A mammalian RNA editing enzyme , 1996, Nature.
[141] J. Chen,et al. Molecular analysis of cDNA molecules encoding glutamate receptor subunits, fGluR1 alpha and fGluR1 beta, of Oreochromis sp. , 1996, DNA and cell biology.
[142] Dirk Feldmeyer,et al. Early-Onset Epilepsy and Postnatal Lethality Associated with an Editing-Deficient GluR-B Allele in Mice , 1995, Science.
[143] C. Samuel,et al. Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase , 1995, Molecular and cellular biology.
[144] K. Nishikura,et al. Mutagenic Analysis of Double-stranded RNA Adenosine Deaminase, a Candidate Enzyme for RNA Editing of Glutamate-gated Ion Channel Transcripts (*) , 1995, The Journal of Biological Chemistry.
[145] M. Higuchi,et al. Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase , 1995, Molecular and cellular biology.
[146] T Kuner,et al. Control of kinetic properties of AMPA receptor channels by nuclear RNA editing. , 1994, Science.
[147] K. Nishikura,et al. Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[148] W. Keller,et al. Purification and properties of double-stranded RNA-specific adenosine deaminase from calf thymus. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[149] D. Speicher,et al. Purification and characterization of double-stranded RNA adenosine deaminase from bovine nuclear extracts. , 1994, The Journal of biological chemistry.
[150] P. Seeburg,et al. RNA editing of AMPA receptor subunit GluR-B: A base-paired intron-exon structure determines position and efficiency , 1993, Cell.
[151] K. Nishikura,et al. Substrate specificity of the dsRNA unwinding/modifying activity. , 1991, The EMBO journal.
[152] J. E. Smith,et al. A double-stranded RNA unwinding activity introduces structural alterations by means of adenosine to inosine conversions in mammalian cells and Xenopus eggs. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[153] Brenda L. Bass,et al. An unwinding activity that covalently modifies its double-stranded RNA substrate , 1988, Cell.
[154] Roberto Cattaneo,et al. Biased hypermutation and other genetic changes in defective measles viruses in human brain infections , 1988, Cell.
[155] D. Melton,et al. Antisense RNA injections in fertilized frog eggs reveal an RNA duplex unwinding activity , 1987, Cell.
[156] Brenda L. Bass,et al. A developmentally regulated activity that unwinds RNA duplexes , 1987, Cell.
[157] R. Benne,et al. Major transcript of the frameshifted coxll gene from trypanosome mitochondria contains four nucleotides that are not encoded in the DNA , 1986, Cell.