Regulatory and Signaling Properties of the Vav Family
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[1] X. Bustelo,et al. Tyrosine Phosphorylation Mediates Both Activation and Downmodulation of the Biological Activity of Vav , 2000, Molecular and Cellular Biology.
[2] A. Weiss,et al. A Guanine Nucleotide Exchange Factor-independent Function of Vav1 in Transcriptional Activation* , 2000, The Journal of Biological Chemistry.
[3] X. Bustelo,et al. Biological and Regulatory Properties of Vav-3, a New Member of the Vav Family of Oncoproteins , 1999, Molecular and Cellular Biology.
[4] T. Hunter,et al. The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase. , 1999, Science.
[5] Richard Treisman,et al. Signal-Regulated Activation of Serum Response Factor Is Mediated by Changes in Actin Dynamics , 1999, Cell.
[6] M. Gimona,et al. N‐terminally truncated Vav induces the formation of depolymerization‐resistant actin filaments in NIH 3T3 cells , 1999, FEBS letters.
[7] T. Tan,et al. Tyrosine phosphorylation of Vav stimulates IL-6 production in mast cells by a Rac/c-Jun N-terminal kinase-dependent pathway. , 1999, Journal of immunology.
[8] Jian Zhang,et al. TCR and CD28 are coupled via ZAP-70 to the activation of the Vav/Rac-1-/PAK-1/p38 MAPK signaling pathway. , 1999, Journal of immunology.
[9] L. Brass,et al. PAR1 activation initiates integrin engagement and outside-in signalling in megakaryoblastic CHRF-288 cells. , 1999, Biochimica et biophysica acta.
[10] M. Fujimoto,et al. CD19 amplifies B lymphocyte signal transduction by regulating Src-family protein tyrosine kinase activation. , 1999, Journal of immunology.
[11] Tony Pawson,et al. Signaling Networks—Do All Roads Lead to the Same Genes? , 1999, Cell.
[12] G. Koretzky,et al. SLP-76 and Vav Function in Separate, but Overlapping Pathways to Augment Interleukin-2 Promoter Activity* , 1999, The Journal of Biological Chemistry.
[13] R. Abraham,et al. Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line. , 1999, International immunology.
[14] B. Kaina,et al. Rho GTPases are over‐expressed in human tumors , 1999, International journal of cancer.
[15] N. Varin‐Blank,et al. hSiah2 Is a New Vav Binding Protein Which Inhibits Vav-Mediated Signaling Pathways , 1999, Molecular and Cellular Biology.
[16] K. Tedford,et al. The oncogene product Vav is a crucial regulator of primary cytotoxic T cell responses but has no apparent role in CD28‐mediated co‐stimulation , 1999, European journal of immunology.
[17] Y. Kaziro,et al. G protein βγ subunit-dependent Rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25Mm , 1999 .
[18] H. Schaeffer,et al. Mitogen-Activated Protein Kinases: Specific Messages from Ubiquitous Messengers , 1999, Molecular and Cellular Biology.
[19] R. Perona,et al. Activation of Serum Response Factor by RhoA Is Mediated by the Nuclear Factor-κB and C/EBP Transcription Factors* , 1999, The Journal of Biological Chemistry.
[20] M. Turner,et al. The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathways. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[21] L. Frati,et al. Role for the Rac1 exchange factor Vav in the signaling pathways leading to NK cell cytotoxicity. , 1999, Journal of immunology.
[22] Michael J. Eck,et al. Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase , 1999, Nature.
[23] Eric O Long,et al. Essential role of LAT in T cell development. , 1999, Immunity.
[24] J. Gutkind,et al. A Novel PDZ Domain Containing Guanine Nucleotide Exchange Factor Links Heterotrimeric G Proteins to Rho* , 1999, The Journal of Biological Chemistry.
[25] K. Okkenhaug,et al. Socs1 binds to multiple signalling proteins and suppresses Steel factor‐dependent proliferation , 1999, The EMBO journal.
[26] E. Gelfand,et al. Activation of Vav and Ras through the nerve growth factor and B cell receptors by different kinases. , 1999, Cellular immunology.
[27] K. Toellner,et al. Defective immunoglobulin class switching in Vav‐deficient mice is attributable to compromised T cell help , 1999, European journal of immunology.
[28] D. Williams,et al. Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense. , 1999, Immunity.
[29] C. Rudd. Adaptors and Molecular Scaffolds in Immune Cell Signaling , 1999, Cell.
[30] A. Weiss,et al. Interdomain B in ZAP-70 Regulates but Is Not Required for ZAP-70 Signaling Function in Lymphocytes , 1999, Molecular and Cellular Biology.
[31] T. Satoh,et al. G protein bg subunit-dependent Rac-guanine nucleotide exchange activity of Ras-GRF1yCDC25Mm , 1999 .
[32] Andrew C. Chan,et al. BLNK Required for Coupling Syk to PLCγ2 and Rac1-JNK in B Cells , 1999 .
[33] T. Kurosaki,et al. BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells. , 1999, Immunity.
[34] Kenji Nakamura,et al. Rac1 is required for the formation of three germ layers during gastrulation , 1998, Oncogene.
[35] J. Penninger,et al. Vav Regulates Peptide-specific Apoptosis in Thymocytes , 1998, The Journal of experimental medicine.
[36] J. Brugge,et al. Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1 , 1998, Current Biology.
[37] Z. Kam,et al. c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor. , 1998, Genes & development.
[38] L. Tuosto,et al. Fyn and ZAP-70 Are Required for Vav Phosphorylation in T Cells Stimulated by Antigen-presenting Cells* , 1998, The Journal of Biological Chemistry.
[39] K. Schuebel,et al. Phosphorylation‐dependent and constitutive activation of Rho proteins by wild‐type and oncogenic Vav‐2 , 1998, The EMBO journal.
[40] B. Mayer,et al. Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76. , 1998, Immunity.
[41] A. Weiss,et al. LAT Is Required for TCR-Mediated Activation of PLCγ1 and the Ras Pathway , 1998 .
[42] A. Weiss,et al. The Syk family of protein tyrosine kinases in T‐cell activation and development , 1998, Immunological reviews.
[43] T. Mak,et al. Thymocyte selection in Vav and IRF‐1 gene‐deficient mice , 1998, Immunological reviews.
[44] W. Langdon,et al. c‐Cbl: A regulator of T cell receptor‐mediated signalling , 1998, Immunology and cell biology.
[45] M. Nagano,et al. Mutagenic analysis of Vav reveals that an intact SH3 domain is required for transformation , 1998, Oncogene.
[46] Channing J Der,et al. Rho family proteins and Ras transformation: the RHOad less traveled gets congested , 1998, Oncogene.
[47] C. Walsh,et al. PAK3 mutation in nonsyndromic X-linked mental retardation , 1998, Nature Genetics.
[48] J. C. Pratt,et al. The Small GTP-Binding Protein Rho Potentiates AP-1 Transcription in T Cells , 1998, Molecular and Cellular Biology.
[49] X. Bustelo,et al. The Vav–Rac1 Pathway in Cytotoxic Lymphocytes Regulates the Generation of Cell-mediated Killing , 1998, The Journal of experimental medicine.
[50] Y. Samuels,et al. Co‐stimulation‐dependent activation of a JNK‐kinase in T lymphocytes , 1998, European journal of immunology.
[51] M. Fujimoto,et al. CD19 regulates B lymphocyte responses to transmembrane signals. , 1998, Seminars in immunology.
[52] S. Bagrodia,et al. Cytoskeletal Reorganization by G Protein-Coupled Receptors Is Dependent on Phosphoinositide 3-Kinase γ, a Rac Guanosine Exchange Factor, and Rac , 1998, Molecular and Cellular Biology.
[53] K. Tedford,et al. Vav links antigen-receptor signaling to the actin cytoskeleton. , 1998, Seminars in immunology.
[54] L. Samelson,et al. LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation. , 1998, Immunity.
[55] F. Alt,et al. Impaired Viability and Profound Block in Thymocyte Development in Mice Lacking the Adaptor Protein SLP-76 , 1998, Cell.
[56] A. Weiss,et al. Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell. , 1998, Science.
[57] T. Stradal,et al. CH domains revisited , 1998, FEBS letters.
[58] D. Kioussis,et al. Altered peptide ligands induce quantitatively but not qualitatively different intracellular signals in primary thymocytes. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[59] E. Stanley,et al. Colony-stimulating Factor-1 Stimulates the Formation of Multimeric Cytosolic Complexes of Signaling Proteins and Cytoskeletal Components in Macrophages* , 1998, The Journal of Biological Chemistry.
[60] C. Turck,et al. BLNK: a central linker protein in B cell activation. , 1998, Immunity.
[61] A. Gilman,et al. p115 RhoGEF, a GTPase activating protein for Gα12 and Gα13 , 1998 .
[62] G. Pedraza-Alva,et al. T Cell Activation through the CD43 Molecule Leads to Vav Tyrosine Phosphorylation and Mitogen-activated Protein Kinase Pathway Activation* , 1998, The Journal of Biological Chemistry.
[63] R. Xavier,et al. Membrane compartmentation is required for efficient T cell activation. , 1998, Immunity.
[64] R. Perona,et al. Multiple Signalling Pathways Lead to the Activation of the Nuclear Factor κB by the Rho Family of GTPases* , 1998, The Journal of Biological Chemistry.
[65] F. Alt,et al. Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction , 1998, Current Biology.
[66] K. Tedford,et al. Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor , 1998, Current Biology.
[67] D. Fearon,et al. CD19 as a membrane-anchored adaptor protein of B lymphocytes: costimulation of lipid and protein kinases by recruitment of Vav. , 1998, Immunity.
[68] E. Vellenga,et al. Signaling through CD5 Activates a Pathway Involving Phosphatidylinositol 3-Kinase, Vav, and Rac1 in Human Mature T Lymphocytes , 1998, Molecular and Cellular Biology.
[69] M. Schwartz,et al. Regulation of inositol lipid kinases by Rho and Rac. , 1998, Current opinion in genetics & development.
[70] M. White,et al. Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav. , 1998, Science.
[71] D. Bar-Sagi,et al. Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos. , 1998, Science.
[72] A. Hall,et al. Rho GTPases and the actin cytoskeleton. , 1998, Science.
[73] L. Samelson,et al. LAT The ZAP-70 Tyrosine Kinase Substrate that Links T Cell Receptor to Cellular Activation , 1998, Cell.
[74] Mary J. Tharayil,et al. Growth Factor Receptor-bound Protein 2 SH2/SH3 Domain Binding to CD28 and Its Role in Co-signaling* , 1998, The Journal of Biological Chemistry.
[75] A. Weiss,et al. LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. , 1998, Immunity.
[76] S. Narumiya,et al. Overexpression of the rhoC gene correlates with progression of ductal adenocarcinoma of the pancreas. , 1998, British Journal of Cancer.
[77] S. Goff,et al. The Thrombopoietin Receptor Can Mediate Proliferation without Activation of the Jak-STAT Pathway , 1997, The Journal of experimental medicine.
[78] S. Sato,et al. CD19 and CD22 expression reciprocally regulates tyrosine phosphorylation of Vav protein during B lymphocyte signaling. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[79] M. Barbacid,et al. Cbl-b, a member of the Sli-1/c-Cbl protein family, inhibits Vav-mediated c-Jun N-terminal kinase activation , 1997, Oncogene.
[80] R. Zamoyska,et al. A requirement for the Rho-family GTP exchange factor Vav in positive and negative selection of thymocytes. , 1997, Immunity.
[81] L. Van Aelst,et al. Rho GTPases and signaling networks. , 1997, Genes & development.
[82] G. Koretzky,et al. Three domains of SLP-76 are required for its optimal function in a T cell line. , 1997, Journal of immunology.
[83] T. Mak,et al. Proto-oncoprotein Vav interacts with c-Cbl in activated thymocytes and peripheral T cells. , 1997, Journal of immunology.
[84] R. Carter,et al. Role of CD19 tyrosine 391 in synergistic activation of B lymphocytes by coligation of CD19 and membrane Ig. , 1997, Journal of immunology.
[85] P. Leibson. Signal transduction during natural killer cell activation: inside the mind of a killer. , 1997, Immunity.
[86] Jun Wu,et al. The Vav Binding Site (Y315) in ZAP-70 Is Critical for Antigen Receptor–mediated Signal Transduction , 1997, The Journal of experimental medicine.
[87] A. Hall,et al. The GTPase Rho has a critical regulatory role in thymus development , 1997, The EMBO journal.
[88] G. Radda,et al. CD40-triggered protein tyrosine phosphorylation on Vav and on phosphatidylinositol 3-kinase correlates with survival of the Ramos-Burkitt lymphoma B cell line. , 1997, Cellular immunology.
[89] John G. Collard,et al. Regulated Membrane Localization of Tiam1, Mediated by the NH2-terminal Pleckstrin Homology Domain, Is Required for Rac-dependent Membrane Ruffling and C-Jun NH2-terminal Kinase Activation , 1997, The Journal of cell biology.
[90] K. Robbins,et al. Tyrosine Phosphorylation of the vav Proto-oncogene Product Links FcεRI to the Rac1-JNK Pathway* , 1997, The Journal of Biological Chemistry.
[91] L. Samelson,et al. The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase. , 1997, Science.
[92] C. Der,et al. Lck regulates Vav activation of members of the Rho family of GTPases , 1997, Molecular and cellular biology.
[93] M. Saraste,et al. Crystal structure of a calponin homology domain , 1997, Nature Structural Biology.
[94] O. Yoshida,et al. Expression of a novel isoform of Vav, Vav-T, containing a single Src homology 3 domain in murine testicular germ cells , 1997, Oncogene.
[95] C. Rudd,et al. Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2. , 1997, Immunity.
[96] M. Hibi,et al. Vav is associated with signal transducing molecules gp130, Grb2 and Erk2, and is tyrosine phosphorylated in response to interleukin‐6 , 1997, FEBS letters.
[97] K. Schuebel,et al. Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product , 1997, Nature.
[98] P. Hogan,et al. Transcription factors of the NFAT family: regulation and function. , 1997, Annual review of immunology.
[99] B. Antonny,et al. A human exchange factor for ARF contains Sec7- and pleckstrin-homology domains , 1996, Nature.
[100] T. Mustelin,et al. Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product. , 1996, Immunity.
[101] F. Romero,et al. Structure and function of vav. , 1996, Cellular signalling.
[102] M. Olson,et al. Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases , 1996, Current Biology.
[103] J. Rivera,et al. Association of a p95 Vav-containing signaling complex with the FcepsilonRI gamma chain in the RBL-2H3 mast cell line. Evidence for a constitutive in vivo association of Vav with Grb2, Raf-1, and ERK2 in an active complex. , 1996, The Journal of biological chemistry.
[104] H. Miyazaki,et al. Functional analysis of the cytoplastic domain of the human Mpl receptor for tyrosine‐phosphorylation of the signaling molecules, proliferation and differentiation , 1996 .
[105] G. Koretzky,et al. Differential Regulation of Activation-induced Tyrosine Phosphorylation and Recruitment of SLP-76 to Vav by Distinct Isoforms of the CD45 Protein-tyrosine Phosphatase* , 1996, The Journal of Biological Chemistry.
[106] A. Chong,et al. Vav in natural killer cells is tyrosine phosphorylated upon cross-linking of Fc gamma RIIIA and is constitutively associated with a serine/threonine kinase. , 1996, The Biochemical journal.
[107] L. Tuosto,et al. p95vav associates with tyrosine-phosphorylated SLP-76 in antigen- stimulated T cells , 1996, The Journal of experimental medicine.
[108] K. Siminovitch,et al. Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase , 1996, The Journal of experimental medicine.
[109] M. Barbacid,et al. Rac-1 dependent stimulation of the JNK/SAPK signaling pathway by Vav. , 1996, Oncogene.
[110] K. Schuebel,et al. Isolation and characterization of murine vav2, a member of the vav family of proto-oncogenes. , 1996, Oncogene.
[111] J. Wu,et al. Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation. , 1996, Immunity.
[112] Y. Zheng,et al. The Dbl family of oncogenes. , 1996, Current opinion in cell biology.
[113] C. Hofmann,et al. Insulin-like growth factor-1 induces rapid tyrosine phosphorylation of the vav proto-oncogene product. , 1996, Experimental hematology.
[114] J. Brugge,et al. Thrombin Receptor Activation and Integrin Engagement Stimulate Tyrosine Phosphorylation of the Proto-oncogene Product, p95, in Platelets (*) , 1996, The Journal of Biological Chemistry.
[115] U. Francke,et al. Wiskott–Aldrich Syndrome Protein, a Novel Effector for the GTPase CDC42Hs, Is Implicated in Actin Polymerization , 1996, Cell.
[116] T. Pawson,et al. The Tyrosine Phosphatase PTP1C Associates with Vav, Grb2, and mSos1 in Hematopoietic Cells (*) , 1996, The Journal of Biological Chemistry.
[117] C. Marshall. Ras effectors. , 1996, Current opinion in cell biology.
[118] H. Miyazaki,et al. Functional analysis of the cytoplasmic domain of the human Mpl receptor for tyrosine-phosphorylation of the signaling molecules, proliferation and differentiation. , 1996, FEBS letters.
[119] X. Bustelo,et al. The VAV family of signal transduction molecules. , 1996, Critical reviews in oncogenesis.
[120] K. Todokoro,et al. Thrombopoietin induces activation of at least two distinct signaling pathways , 1995, FEBS letters.
[121] M. Xia,et al. Megakaryocyte growth and development factor and interleukin-3 induce patterns of protein-tyrosine phosphorylation that correlate with dominant differentiation over proliferation of mpl-transfected 32D cells. , 1995, Blood.
[122] Y. Yazaki,et al. TPO/c-mpl ligand induces tyrosine phosphorylation of multiple cellular proteins including proto-oncogene products, Vav and c-Cbl, and Ras signaling molecules. , 1995, Biochemical and biophysical research communications.
[123] M. Saraste,et al. Does Vav bind to F‐actin through a CH domain? , 1995, FEBS letters.
[124] J. Camonis,et al. The proline-rich region of Vav binds to Grb2 and Grb3-3. , 1995, Oncogene.
[125] S. Schreiber,et al. Signal transduction in T lymphocytes using a conditional allele of Sos. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[126] S. Goff,et al. TPO and IL-3 induce overlapping but distinct protein tyrosine phosphorylation in a myeloid precursor cell line. , 1995, Biochemical and biophysical research communications.
[127] N. Gusev,et al. Interaction of smooth muscle calponin with phospholipids , 1995, FEBS letters.
[128] H. Mano,et al. Interleukin 3 and erythropoietin induce association of Vav with Tec kinase through Tec homology domain. , 1995, Oncogene.
[129] J. Ihle. The Janus protein tyrosine kinases in hematopoietic cytokine signaling. , 1995, Seminars in immunology.
[130] J. Wu,et al. A functional T-cell receptor signaling pathway is required for p95vav activity , 1995, Molecular and cellular biology.
[131] R. Prywes,et al. Serum response factor: transcriptional regulation of genes induced by growth factors and differentiation. , 1995, Biochimica et biophysica acta.
[132] D. Fearon,et al. A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP. , 1995, Science.
[133] A. Yuo,et al. Tyrosine phosphorylation of vav protooncogene product in primary human myelogenous leukemic cells stimulated by granulocyte colony-stimulating factor. , 1995, Biochemical and biophysical research communications.
[134] D. L. Sokol,et al. Vav Is Necessary for Prolactin-stimulated Proliferation and Is Translocated into the Nucleus of a T-cell Line (*) , 1995, The Journal of Biological Chemistry.
[135] J. Kinet,et al. A Requirement for Syk in the Activation of the Microtubule-associated Protein Kinase/Phospholipase A2 Pathway by FcεR1 Is Not Shared by a G Protein-coupled Receptor (*) , 1995, The Journal of Biological Chemistry.
[136] K. Yamana,et al. Interaction of calponin with phospholipids. , 1995, Journal of biochemistry.
[137] M. White,et al. Insulin-dependent Tyrosine Phosphorylation of the vav Proto-oncogene Product in Cells of Hematopoietic Origin (*) , 1995, The Journal of Biological Chemistry.
[138] M. Barbacid,et al. Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+CDS+thymocytes , 1995, Nature.
[139] F. Alt,et al. Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene , 1995, Nature.
[140] K. Rajewsky,et al. Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav , 1995, Nature.
[141] B. Druker,et al. Tyrosine phosphorylation of p95Vav in myeloid cells is regulated by GM‐CSF, IL‐3 and steel factor and is constitutively increased by p210BCR/ABL. , 1995, The EMBO journal.
[142] J. Haines,et al. Identification of VAV2 on 9q34 and its exclusion as the tuberous sclerosis gene TSC1 , 1994, Annals of human genetics.
[143] T. Lebien,et al. Signaling through CD19 activates Vav/mitogen-activated protein kinase pathway and induces formation of a CD19/Vav/phosphatidylinositol 3-kinase complex in human B cell precursors. , 1994, The Journal of biological chemistry.
[144] A. Weiss,et al. The protein tyrosine kinase ZAP-70 can associate with the SH2 domain of proto-Vav. , 1994, The Journal of biological chemistry.
[145] D. Baltimore,et al. Binding of Vav to Grb2 through dimerization of Src homology 3 domains. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[146] S. Orkin,et al. Hematopoietic development of vav-/- mouse embryonic stem cells. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[147] J. Ihle,et al. Induction of tyrosine phosphorylation of Vav and expression of Pim-1 correlates with Jak2-mediated growth signaling from the erythropoietin receptor. , 1994, Blood.
[148] T. Watanabe,et al. IL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus 2 kinases , 1994, The Journal of experimental medicine.
[149] R. Stevenson,et al. Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: A putative Rho Rac guanine nucleotide exchange factor , 1994, Cell.
[150] C. Der,et al. Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras , 1994, Molecular and cellular biology.
[151] G. Mills,et al. CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[152] D. Olive,et al. The role of p21ras in CD28 signal transduction: triggering of CD28 with antibodies, but not the ligand B7-1, activates p21ras , 1994, The Journal of experimental medicine.
[153] A. Altman,et al. Monocyte deactivation by interleukin 10 via inhibition of tyrosine kinase activity and the Ras signaling pathway. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[154] M. Barbacid,et al. Vav cooperates with Ras to transform rodent fibroblasts but is not a Ras GDP/GTP exchange factor. , 1994, Oncogene.
[155] B. Druker,et al. Vav binds to several SH2/SH3 containing proteins in activated lymphocytes. , 1994, Oncogene.
[156] W. Kuo,et al. ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency. , 1994, Science.
[157] T. Pawson,et al. Substrate specificities and identification of a putative binding site for PI3K in the carboxy tail of the murine Flt3 receptor tyrosine kinase. , 1994, Oncogene.
[158] T Pawson,et al. Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav , 1994, Molecular and cellular biology.
[159] R. Durbin,et al. 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans , 1994, Nature.
[160] L. Platanias,et al. Interferon alpha induces rapid tyrosine phosphorylation of the vav proto-oncogene product in hematopoietic cells. , 1994, The Journal of biological chemistry.
[161] R. Treisman. Ternary complex factors: growth factor regulated transcriptional activators. , 1994, Current opinion in genetics & development.
[162] Mark S. Boguski,et al. Proteins regulating Ras and its relatives , 1993, Nature.
[163] G. Schieven,et al. Cross-linking of Fc gamma receptor I (Fc gamma RI) and receptor II (Fc gamma RII) on monocytic cells activates a signal transduction pathway common to both Fc receptors that involves the stimulation of p72 Syk protein tyrosine kinase. , 1993, The Journal of biological chemistry.
[164] I. Lemischka,et al. Mitogenic signalling and substrate specificity of the Flk2/Flt3 receptor tyrosine kinase in fibroblasts and interleukin 3-dependent hematopoietic cells , 1993, Molecular and cellular biology.
[165] W. Farrar,et al. Interleukin-2 induces tyrosine phosphorylation of the vav proto-oncogene product in human T cells: lack of requirement for the tyrosine kinase lck. , 1993, The Biochemical journal.
[166] M. Barbacid,et al. Steel factor stimulates the tyrosine phosphorylation of the proto-oncogene product, p95vav, in human hemopoietic cells. , 1992, The Journal of biological chemistry.
[167] M. Barbacid,et al. Tyrosine Phosphorylation of the vav Proto-Oncogene Product in Activated B Cells , 1992, Science.
[168] L. Herzenberg,et al. Differential development of progenitor activity for three B-cell lineages. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[169] A. Ullrich,et al. Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs , 1992, Nature.
[170] M. Barbacid,et al. Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates , 1992, Nature.
[171] J. Cleveland,et al. Loss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potential , 1991, Molecular and cellular biology.
[172] M. Barbacid,et al. Mechanism of activation of the vav protooncogene. , 1991, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[173] M. Barbacid,et al. vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells. , 1989, The EMBO journal.
[174] p 95 vav Associates with Tyrosine-phosphorylated SLP-76 in Antigen-st imulated T Cells , 2022 .