Endothelial HIF-2α regulates murine pathological angiogenesis and revascularization processes.
暂无分享,去创建一个
Brian Keith | Arjun G Yodh | Steven Schenkel | Rickson C Mesquita | Meeri N Kim | A. Yodh | Meeri N. Kim | R. Mesquita | Steven S. Schenkel | B. Krock | M. Simon | B. Keith | N. Skuli | Amar J. Majmundar | Nicolas Skuli | M Celeste Simon | Liping Liu | A. Runge | Jiaming Liang | Lijoy K. Mathew | Zachary L. Quinn | Liping Liu | Anja Runge | Amar J Majmundar | Bryan L Krock | Lijoy K Mathew | Zachary L Quinn | Jiaming Liang | A. G. Yodh | Z. Quinn | Nicolas Skuli
[1] Thomas Korff,et al. Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hind-limb ischemia , 2009, Nature Protocols.
[2] W. Pu,et al. Therapeutic neovascularization for peripheral arterial diseases: advances and perspectives. , 2007, Histology and histopathology.
[3] G. Semenza,et al. Purification and Characterization of Hypoxia-inducible Factor 1 (*) , 1995, The Journal of Biological Chemistry.
[4] H. Gerhardt,et al. Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting , 2010, Nature Cell Biology.
[5] G. Melillo. Targeting hypoxia cell signaling for cancer therapy , 2007, Cancer and Metastasis Reviews.
[6] Y. Fujii‐Kuriyama,et al. Hypoxia-inducible Transcription Factor-2α in Endothelial Cells Regulates Tumor Neovascularization through Activation of Ephrin A1* , 2008, Journal of Biological Chemistry.
[7] M. Simon,et al. Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis. , 2009, Blood.
[8] O. Gavrilova,et al. Disruption of the Arnt gene in endothelial cells causes hepatic vascular defects and partial embryonic lethality in mice , 2006, Hepatology.
[9] A. Giaccia,et al. Notch1 is an effector of Akt and hypoxia in melanoma development. , 2008, The Journal of clinical investigation.
[10] M. Fruttiger,et al. Oxygen-induced retinopathy: a model for vascular pathology in the retina , 2010, Eye.
[11] W. Schaper,et al. Blood monocyte concentration is critical for enhancement of collateral artery growth. , 2002, American journal of physiology. Heart and circulatory physiology.
[12] T. Kadesch,et al. Inhibition of myogenesis by Notch: Evidence for multiple pathways , 2009, Journal of cellular physiology.
[13] Howard Hughes. The Howard Hughes Medical Institute , 1996, Current Biology.
[14] R. Johnson,et al. Acute postnatal ablation of Hif-2α results in anemia , 2007, Proceedings of the National Academy of Sciences.
[15] Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice , 2010 .
[16] D. Mooney,et al. Promoting angiogenesis via manipulation of VEGF responsiveness with notch signaling. , 2009, Biomaterials.
[17] A. Al Haj Zen,et al. Inhibition of Delta-Like-4–Mediated Signaling Impairs Reparative Angiogenesis After Ischemia , 2010, Circulation research.
[18] Brian Keith,et al. HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression , 2011, Nature Reviews Cancer.
[19] S. Harding,et al. Anti-VEGF compounds in the treatment of neovascular age related macular degeneration. , 2011, Current drug targets.
[20] M. Simon,et al. HIF-1α versus HIF-2α in endothelial cells and vascular functions: Is there a master in angiogenesis regulation? , 2009 .
[21] S. Nishikawa,et al. Adrenomedullin/Cyclic AMP Pathway Induces Notch Activation and Differentiation of Arterial Endothelial Cells From Vascular Progenitors , 2006, Arteriosclerosis, thrombosis, and vascular biology.
[22] Elizabeth Selvin,et al. Prevalence of and Risk Factors for Peripheral Arterial Disease in the United States: Results From the National Health and Nutrition Examination Survey, 1999–2000 , 2004, Circulation.
[23] R. Conaway,et al. Multiple Splice Variants of the Human HIF-3α Locus Are Targets of the von Hippel-Lindau E3 Ubiquitin Ligase Complex* , 2003, The Journal of Biological Chemistry.
[24] Frederik De Smet,et al. Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization , 2009, Cell.
[25] Robert A. Harris,et al. Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism , 2008, Nature Genetics.
[26] Elizabeth Selvin,et al. Prevalence of and Risk Factors for Peripheral Arterial Disease in the United States: Results From the National Health and Nutrition Examination Survey, 1999–2000 , 2004 .
[27] H. Drexler,et al. Notch Ligand Delta-Like 1 Is Essential for Postnatal Arteriogenesis , 2007, Circulation research.
[28] B. Krock,et al. Hypoxia-induced angiogenesis: good and evil. , 2011, Genes & cancer.
[29] Nupura S. Bhise,et al. Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia , 2009, Proceedings of the National Academy of Sciences.
[30] N. Greenberg,et al. Conditional activation of FGFR1 in the prostate epithelium induces angiogenesis with concomitant differential regulation of Ang-1 and Ang-2 , 2007, Oncogene.
[31] D. Hinton,et al. Chan, C.K. et al. Differential expression of pro- and antiangiogenic factors in mouse strain-dependent hypoxia-induced retinal neovascularization. Lab. Invest. 85, 721-733 , 2005 .
[32] D. Guidolin,et al. Adrenomedullin stimulates angiogenic response in cultured human vascular endothelial cells: Involvement of the vascular endothelial growth factor receptor 2 , 2008, Peptides.
[33] U. Lendahl,et al. Hypoxia requires notch signaling to maintain the undifferentiated cell state. , 2005, Developmental cell.
[34] R. Johnson,et al. Acute postnatal ablation of Hif-2alpha results in anemia. , 2007, Proceedings of the National Academy of Sciences of the United States of America.
[35] A. Hoffmann,et al. Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis. , 2010, Genes & development.
[36] John P. Cooke,et al. Murine Model of Hindlimb Ischemia , 2009, Journal of visualized experiments : JoVE.
[37] Nan Tang,et al. Loss of HIF-1α in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis , 2004 .
[38] A. Yodh,et al. Hemodynamic and metabolic diffuse optical monitoring in a mouse model of hindlimb ischemia , 2010, Biomedical optics express.
[39] S. McKnight,et al. Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. , 1997, Genes & development.
[40] G. Semenza,et al. Effects of Aging and Hypoxia-Inducible Factor-1 Activity on Angiogenic Cell Mobilization and Recovery of Perfusion After Limb Ischemia , 2007, Circulation research.
[41] H. Verheul,et al. Anti-angiogenic tyrosine kinase inhibitors: what is their mechanism of action? , 2009, Angiogenesis.
[42] K. Alitalo,et al. Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis , 2011, Nature.
[43] Fu-Jung Lin,et al. Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity , 2005, Nature.
[44] D. Hinton,et al. Differential expression of pro- and antiangiogenic factors in mouse strain-dependent hypoxia-induced retinal neovascularization , 2005, Laboratory Investigation.
[45] R. Lechler,et al. Isolation of endothelial cells from murine tissue. , 2000, Journal of immunological methods.
[46] P. Carmeliet,et al. VE‐Cadherin‐Cre‐recombinase transgenic mouse: A tool for lineage analysis and gene deletion in endothelial cells , 2006, Developmental dynamics : an official publication of the American Association of Anatomists.
[47] Peter Carmeliet,et al. Angiogenesis in life, disease and medicine , 2005, Nature.
[48] K. Olive,et al. Heterozygosity for hypoxia inducible factor 1alpha decreases the incidence of thymic lymphomas in a p53 mutant mouse model. , 2009, Cancer research.
[49] T. Kume. Novel insights into the differential functions of Notch ligands in vascular formation , 2009, Journal of angiogenesis research.
[50] A. Fischer,et al. Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate. , 2007, Experimental cell research.
[51] P. Gimotty,et al. Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation. , 2010, The Journal of clinical investigation.
[52] John D Gordan,et al. HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity. , 2007, Cancer cell.
[53] W. Leenders,et al. Targeted therapies of cancer: angiogenesis inhibition seems not enough. , 2010, Cancer letters.
[54] A. Chadli. THE CANCER CELL , 1924, La Presse medicale.
[55] A. Bhandoola,et al. Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss. , 2007, Cell stem cell.
[56] M. Simon,et al. Regulation of angiogenesis by hypoxia and hypoxia-inducible factors. , 2006, Current topics in developmental biology.
[57] I. Zachary,et al. Therapeutic angiogenesis for cardiovascular disease: biological context, challenges, prospects , 2010, Heart.
[58] Gayathri Balasundaram,et al. Direct Isolation, Culture and Transplant of Mouse Skeletal Muscle Derived Endothelial Cells with Angiogenic Potential , 2008, PloS one.
[59] S. Goerdt,et al. Knockout of HIF-1α in tumor-associated macrophages enhances M2 polarization and attenuates their pro-angiogenic responses. , 2010, Carcinogenesis.
[60] W. R. Taylor,et al. Angiopoietin-2 Stimulates Blood Flow Recovery After Femoral Artery Occlusion by Inducing Inflammation and Arteriogenesis , 2008, Arteriosclerosis, thrombosis, and vascular biology.
[61] K. Nathanson,et al. HIF2α inhibition promotes p53 pathway activity, tumor cell death, and radiation responses , 2009, Proceedings of the National Academy of Sciences.
[62] T. Kadesch,et al. Regulation of skeletal myogenesis by Notch. , 2010, Experimental cell research.
[63] W. Wong,et al. Hypoxia-inducible factors and the response to hypoxic stress. , 2010, Molecular cell.
[64] M. Celeste Simon,et al. The impact of O2 availability on human cancer , 2008, Nature Reviews Cancer.
[65] M. Simon,et al. HIF-1alpha versus HIF-2alpha in endothelial cells and vascular functions: is there a master in angiogenesis regulation? , 2009, Cell Cycle.
[66] T. Sacktor. How does PKMζ maintain long-term memory? , 2011, Nature Reviews Neuroscience.
[67] Gavin Thurston,et al. The Delta paradox: DLL4 blockade leads to more tumour vessels but less tumour growth , 2007, Nature Reviews Cancer.
[68] Gavin Thurston,et al. Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis , 2006, Nature.