Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl]thiazolidine): a highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.
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H. Utsumi | S. Kiuchi | Yoshinobu Nakamaru | N. Masutomi | T. Ishige | H. Sakashita | Sayaka Fukuda | Kumiko Yoshida | H. Kitajima | F. Akahoshi | J. Anabuki | Yuji Abe | S. Ishii | Tomohiro Yoshida | T. Murozono | K. Kosaka | Yoshiharu Hayashi | Yoshihito Tanaka | M. Nakamura | S. Sonda | M. Takeuchi | Naoko Ueda | Sumie Sekiguchi | K. Shima | M. Nabeno | A. Soejima | Yoko Takashina | R. Tsutsumiuchi | H. Kishida | I. Miyaguchi | Takahiro Murozono