Impairments in visual discrimination performance and gaze shifts in monkeys with superior colliculus lesions

Eye movements of monkeys were recorded while they performed a visual discrimination task before and after superior colliculus (SC) lesions or control surgery. The monkeys with SC lesions were impaired in orienting their eyes toward the visual stimuli when they were presented eccentrically 15 degrees to 32 degrees from the center of the display screen, toward which their heads were directed. This impairment in shifting the gaze to eccentric stimuli may account for the concomitant deficit in discriminating between these eccentric stimuli. The eye movement deficit appears to depend on destruction of the deep as well as more superficial layers of the SC and may reflect a disturbance in visual-oculomotor coordination.

[1]  M. Goodale,et al.  Attention to novel stimuli in rats with lesions of the superior colliculus , 1974 .

[2]  D. Robinson.  Eye movements evoked by collicular stimulation in the alert monkey. , 1972, Vision research.

[3]  M. Goodale,et al.  Susceptibility to startle during ongoing behaviour following collicular lesions in the rat , 1975, Neuroscience Letters.

[4]  R H Wurtz,et al.  Role of striate cortex and superior colliculus in visual guidance of saccadic eye movements in monkeys. , 1977, Journal of neurophysiology.

[5]  R. Wurtz,et al.  Activity of superior colliculus in behaving monkey. IV. Effects of lesions on eye movements. , 1972, Journal of neurophysiology.

[6]  F. Robert Treichler,et al.  Chapter 1 - Discrete-Trial Training Techniques and Stimulus Variables1 , 1965 .

[7]  R. Wurtz,et al.  Activity of superior colliculus in behaving monkey. 3. Cells discharging before eye movements. , 1972, Journal of neurophysiology.

[8]  D. Meyer,et al.  Effects of stimulus-response isolation on primate pattern discrimination learning. , 1962, Journal of comparative and physiological psychology.

[9]  C. Butter.  Effect of superior colliculus, striate, and prestriate lesions on visual sampling in rhesus monkeys. , 1974, Journal of comparative and physiological psychology.

[10]  L. Young,et al.  Survey of eye movement recording methods , 1975 .

[11]  J. K. Harting.  Descending pathways from the superior colliculus: An autoradiographic analysis in the rhesus monkey (Macaca mulatta) , 1977, The Journal of comparative neurology.

[12]  D. B. Bender,et al.  Localization and detection of visual stimuli following superior colliculus lesions in rhesus monkeys , 1978, Brain Research.

[13]  Melvyn A. Goodale,et al.  The effects of lesions of the superior colliculus on locomotor orientation and the orienting reflex in the rat , 1975, Brain Research.

[14]  T H MEIKLE,et al.  THE ROLE OF THE SUPERIOR COLLICULUS IN VISUALLY GUIDED BEHAVIOR. , 1965, Experimental neurology.

[15]  A. M. Schrier,et al.  Eye movements of monkeys during brightness discrimination and discrimination reversal , 1973 .

[16]  P. Schiller,et al.  Single-unit recording and stimulation in superior colliculus of the alert rhesus monkey. , 1972, Journal of neurophysiology.

[17]  M. P. Bryden,et al.  The role of post-exposural eye movements in tachistoscopic perception. , 1961 .

[18]  H. W. Bond,et al.  Solid miniature silver-silver chloride electrodes for chronic implantation. , 1970, Electroencephalography and clinical neurophysiology.

[19]  C. Gross,et al.  Eye orientation during visual discrimination learning by monkeys. , 1971, Neuropsychologia.

[20]  R. Wurtz,et al.  Activity of superior colliculus in behaving monkey. II. Effect of attention on neuronal responses. , 1972, Journal of neurophysiology.

[21]  J. Büttner-Ennever,et al.  An autoradiographic study of the pathways from the pontine reticular formation involved in horizontal eye movements , 1976, Brain Research.

[22]  H. F. Crovitz,et al.  Tendencies to eye movement and perceptual accuracy. , 1962, Journal of experimental psychology.

[23]  R H Wurtz,et al.  Organization of monkey superior colliculus: intermediate layer cells discharging before eye movements. , 1976, Journal of neurophysiology.

[24]  C. Butter.  Contrasting effects of lateral striate and superior colliculus lesions on visual discrimination performance in rhesus monkeys. , 1979, Journal of comparative and physiological psychology.

[25]  M. Cynader,et al.  Receptive-field organization of monkey superior colliculus. , 1972, Journal of neurophysiology.

[26]  J. L. Conway,et al.  Effects of frontal eye field and superior colliculus ablations on eye movements. , 1979, Science.

[27]  J. Schuck.  Pattern discrimination and visual sampling by the monkey. , 1960, Journal of comparative and physiological psychology.