Vigorous physical activity impairs myocardial function in patients with arrhythmogenic right ventricular cardiomyopathy and in mutation positive family members

Exercise increases risk of ventricular arrhythmia in subjects with arrhythmogenic right ventricular cardiomyopathy (ARVC). We aimed to investigate the impact of exercise on myocardial function in ARVC subjects.

[1]  Ulf Ekelund,et al.  Guide to the assessment of physical activity: Clinical and research applications: a scientific statement from the American Heart Association. , 2013, Circulation.

[2]  Z. Şi̇mşek,et al.  Speckle Tracking Echocardiographic Analysis of Left Ventricular Systolic and Diastolic Functions of Young Elite Athletes with Eccentric and Concentric Type of Cardiac Remodeling , 2013, Echocardiography.

[3]  S. Russell,et al.  Exercise increases age-related penetrance and arrhythmic risk in arrhythmogenic right ventricular dysplasia/cardiomyopathy-associated desmosomal mutation carriers. , 2013, Journal of the American College of Cardiology.

[4]  R. Murphy,et al.  Reduced Right Ventricular Myocardial Strain in the Elite Athlete May Not Be a Consequence of Myocardial Damage. “Cream Masquerades as Skimmed Milk” , 2013, Echocardiography.

[5]  Scott D Flamm,et al.  Standardized image interpretation and post processing in cardiovascular magnetic resonance: Society for Cardiovascular Magnetic Resonance (SCMR) Board of Trustees Task Force on Standardized Post Processing , 2013, Journal of Cardiovascular Magnetic Resonance.

[6]  D. Oxborough,et al.  Physiological Right Ventricular Adaptation in Elite Athletes of African and Afro-Caribbean Origin , 2013, Circulation.

[7]  Hein Heidbuchel,et al.  Ventricular arrhythmias associated with long-term endurance sports: what is the evidence? , 2012, British Journal of Sports Medicine.

[8]  Jan Bogaert,et al.  Exercise-induced right ventricular dysfunction and structural remodelling in endurance athletes. , 2012, European heart journal.

[9]  B. Maron,et al.  Assessment of left ventricular hypertrophy in a trained athlete: differential diagnosis of physiologic athlete's heart from pathologic hypertrophy. , 2012, Progress in cardiovascular diseases.

[10]  Y. Oade,et al.  Arrhythmogenic right ventricular cardiomyopathy , 2011, BMJ Case Reports.

[11]  T. Edvardsen,et al.  Right ventricular mechanical dispersion is related to malignant arrhythmias: a study of patients with arrhythmogenic right ventricular cardiomyopathy and subclinical right ventricular dysfunction. , 2011, European heart journal.

[12]  D. Bluemke,et al.  Physical activity and right ventricular structure and function. The MESA-Right Ventricle Study. , 2011, American journal of respiratory and critical care medicine.

[13]  T. Edvardsen,et al.  Transmural Differences in Myocardial Contraction in Long-QT Syndrome: Mechanical Consequences of Ion Channel Dysfunction , 2010, Circulation.

[14]  H. Heidbuchel,et al.  Lower than expected desmosomal gene mutation prevalence in endurance athletes with complex ventricular arrhythmias of right ventricular origin , 2010, Heart.

[15]  Wojciech Zareba,et al.  Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia: Proposed Modification of the Task Force Criteria , 2010, European heart journal.

[16]  John C Chambers,et al.  Arrhythmogenic cardiomyopathy: etiology, diagnosis, and treatment. , 2010, Annual review of medicine.

[17]  N. Prakken,et al.  Echocardiographic tissue deformation imaging of right ventricular systolic function in endurance athletes. , 2008, European heart journal.

[18]  A. Bauman,et al.  Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. , 2007, Circulation.

[19]  G. Breithardt,et al.  Age- and Training-Dependent Development of Arrhythmogenic Right Ventricular Cardiomyopathy in Heterozygous Plakoglobin-Deficient Mice , 2006, Circulation.

[20]  Richard B Devereux,et al.  Recommendations for chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardio , 2005, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[21]  Yves Schutz,et al.  Metabolic equivalent: one size does not fit all. , 2005, Journal of applied physiology.

[22]  W. Haskell,et al.  Task Force 8: classification of sports. , 2005, Journal of the American College of Cardiology.

[23]  B. Wilkoff,et al.  Differences in Tachyarrhythmia Detection and Implantable Cardioverter Defibrillator Therapy by Primary or Secondary Prevention Indication in Cardiac Resynchronization Therapy Patients , 2004, Journal of cardiovascular electrophysiology.

[24]  Maurizio Schiavon,et al.  Does sports activity enhance the risk of sudden death in adolescents and young adults? , 2003, Journal of the American College of Cardiology.

[25]  H. Heidbuchel,et al.  High prevalence of right ventricular involvement in endurance athletes with ventricular arrhythmias. Role of an electrophysiologic study in risk stratification. , 2003, European heart journal.

[26]  D. Corrado,et al.  Sudden death in young competitive athletes: clinicopathologic correlations in 22 cases. , 1990, The American journal of medicine.

[27]  J. Afilalo,et al.  Guidelines for the Echocardiographic Assessment of the Right Heart in Adults: A Report from the American Society of Echocardiography , 2014 .