论文信息 - Practical concepts of drug absorption, distribution and loss.

Practical concepts of drug absorption, distribution and loss.

Serum concentrations of ampicillin were measured following administration of the drug orally and intravenously to nine normal volunteers. The results were analysed by graphic methods, and the effects of absorption, distribution and loss on the time serum concentration curve are discussed.

[1] W. Jusko,et al. Comparison of ampicillin and hetacillin pharmacokinetics in man. , 1973, Journal of pharmaceutical sciences.

[2] L. Dittert,et al. Pharmacokinetic interpretation of penicillin levels in serum and urine after intravenous administration. , 1969, Antimicrobial agents and chemotherapy.

[3] E. Benner,et al. Simplified, accurate method for antibiotic assay of clinical specimens. , 1966, Applied microbiology.