Hexosamines, insulin resistance, and the complications of diabetes: current status.
暂无分享,去创建一个
[1] Michael Brownlee,et al. The pathobiology of diabetic complications: a unifying mechanism. , 2005, Diabetes.
[2] K. Petersen,et al. Mechanisms of insulin resistance in humans and possible links with inflammation. , 2005, Hypertension.
[3] D. James,et al. Akt activation is required at a late stage of insulin-induced GLUT4 translocation to the plasma membrane. , 2005, Molecular endocrinology.
[4] R. Duggirala,et al. A single nucleotide polymorphism in MGEA5 encoding O-GlcNAc-selective N-acetyl-beta-D glucosaminidase is associated with type 2 diabetes in Mexican Americans. , 2005, Diabetes.
[5] F. Schick,et al. The -913 G/A glutamine:fructose-6-phosphate aminotransferase gene polymorphism is associated with measures of obesity and intramyocellular lipid content in nondiabetic subjects. , 2005, The Journal of clinical endocrinology and metabolism.
[6] D. James. MUNC-ing around with insulin action. , 2005, The Journal of clinical investigation.
[7] A. Paterson,et al. Characterization of the Histone Acetyltransferase (HAT) Domain of a Bifunctional Protein with Activable O-GlcNAcase and HAT Activities*♦ , 2004, Journal of Biological Chemistry.
[8] C. Sweep,et al. Role of hexosamines in insulin resistance and nutrient sensing in human adipose and muscle tissue. , 2004, The Journal of clinical endocrinology and metabolism.
[9] G. Hart,et al. O-GlcNAc Transferase Is in a Functional Complex with Protein Phosphatase 1 Catalytic Subunits* , 2004, Journal of Biological Chemistry.
[10] P. Marchetti,et al. Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells. , 2004, Endocrinology.
[11] G. Parker,et al. Hyperglycemia and Inhibition of Glycogen Synthase in Streptozotocin-treated Mice , 2004, Journal of Biological Chemistry.
[12] B. Witherbee,et al. Activation of the hexosamine signaling pathway in adipose tissue results in decreased serum adiponectin and skeletal muscle insulin resistance. , 2004, Endocrinology.
[13] E. Schleicher,et al. Upstream stimulatory factor (USF) proteins induce human TGF-beta1 gene activation via the glucose-response element-1013/-1002 in mesangial cells: up-regulation of USF activity by the hexosamine biosynthetic pathway. , 2004, The Journal of biological chemistry.
[14] G. Hart,et al. The Coactivator of Transcription CREB-binding Protein Interacts Preferentially with the Glycosylated Form of Stat5* , 2004, Journal of Biological Chemistry.
[15] J. Holloszy,et al. Glucosamine and glucose induce insulin resistance by different mechanisms in rat skeletal muscle. , 2003, American journal of physiology. Endocrinology and metabolism.
[16] M. Fukuda,et al. Diabetes and the Accompanying Hyperglycemia Impairs Cardiomyocyte Calcium Cycling through Increased Nuclear O-GlcNAcylation* , 2003, Journal of Biological Chemistry.
[17] J. Miyazaki,et al. The transcription factor PDX-1 is post-translationally modified by O-linked N-acetylglucosamine and this modification is correlated with its DNA binding activity and insulin secretion in min6 beta-cells. , 2003, Archives of biochemistry and biophysics.
[18] E. Schleicher,et al. Glutamine:fructose-6-phosphate aminotransferase enzyme activity is necessary for the induction of TGF-β1 and fibronectin expression in mesangial cells , 2003, Diabetologia.
[19] Nathan Lamarre-Vincent,et al. Dynamic glycosylation of the transcription factor CREB: a potential role in gene regulation. , 2003, Journal of the American Chemical Society.
[20] G. Parker,et al. Insulin Resistance of Glycogen Synthase Mediated byO-Linked N-Acetylglucosamine* , 2003, The Journal of Biological Chemistry.
[21] H. Hammes,et al. Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy , 2003, Nature Medicine.
[22] K. Schey,et al. High glucose and insulin promote O-GlcNAc modification of proteins, including α-tubulin , 2003 .
[23] Guoli Chen,et al. Glucosamine‐induced insulin resistance is coupled to O‐linked glycosylation of Munc18c , 2003, FEBS letters.
[24] C. Sweep,et al. Muscle uridine diphosphate-hexosamines do not decrease despite correction of hyperglycemia-induced insulin resistance in type 2 diabetes. , 2002, The Journal of clinical endocrinology and metabolism.
[25] R. Hresko,et al. Enhanced O-GlcNAc protein modification is associated with insulin resistance in GLUT1-overexpressing muscles. , 2002, American journal of physiology. Endocrinology and metabolism.
[26] G. Sesti,et al. Insulin-Dependent Activation of Endothelial Nitric Oxide Synthase Is Impaired by O-Linked Glycosylation Modification of Signaling Proteins in Human Coronary Endothelial Cells , 2002, Circulation.
[27] G. Parker,et al. Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[28] Xiaoyong Yang,et al. Recruitment of O-GlcNAc Transferase to Promoters by Corepressor mSin3A Coupling Protein O-GlcNAcylation to Transcriptional Repression , 2002, Cell.
[29] E. Ravussin. Cellular sensors of feast and famine. , 2002, The Journal of clinical investigation.
[30] Zhaohui Feng,et al. Identification of a biochemical link between energy intake and energy expenditure. , 2002, The Journal of clinical investigation.
[31] G. Hart,et al. Dynamic interplay between O-glycosylation and O-phosphorylation of nucleocytoplasmic proteins: alternative glycosylation/phosphorylation of THR-58, a known mutational hot spot of c-Myc in lymphomas, is regulated by mitogens. , 2002, The Journal of biological chemistry.
[32] G. Hart,et al. Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[33] M. Buse,et al. Defective Akt activation is associated with glucose- but not glucosamine-induced insulin resistance. , 2002, American journal of physiology. Endocrinology and metabolism.
[34] M. Buse,et al. Insulin Acutely Regulates Munc18-c Subcellular Trafficking , 2002, The Journal of Biological Chemistry.
[35] G. Hart,et al. Dynamic O-Glycosylation of Nuclear and Cytosolic Proteins , 2002, The Journal of Biological Chemistry.
[36] D. McClain. Hexosamines as mediators of nutrient sensing and regulation in diabetes. , 2002, Journal of diabetes and its complications.
[37] M. Brownlee. Biochemistry and molecular cell biology of diabetic complications , 2001, Nature.
[38] J. Shaw,et al. Global and societal implications of the diabetes epidemic , 2001, Nature.
[39] C. Kahn,et al. Insulin signalling and the regulation of glucose and lipid metabolism , 2001, Nature.
[40] G. Hart,et al. Reciprocity between O-GlcNAc and O-phosphate on the carboxyl terminal domain of RNA polymerase II. , 2001, Biochemistry.
[41] L. Nolte,et al. Development of Glucose-induced Insulin Resistance in Muscle Requires Protein Synthesis* , 2001, The Journal of Biological Chemistry.
[42] Xiaoyong Yang,et al. O-linkage of N-acetylglucosamine to Sp1 activation domain inhibits its transcriptional capability , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[43] P. Span,et al. Short-term glucosamine infusion does not affect insulin sensitivity in humans. , 2001, The Journal of clinical endocrinology and metabolism.
[44] G. Hart,et al. Dynamic O-Glycosylation of Nuclear and Cytosolic Proteins , 2001, The Journal of Biological Chemistry.
[45] Gerald W. Hart,et al. Glycosylation of Nucleocytoplasmic Proteins: Signal Transduction and O-GlcNAc , 2001, Science.
[46] A. Saltiel. New Perspectives into the Molecular Pathogenesis and Treatment of Type 2 Diabetes , 2001, Cell.
[47] F. N. Lee,et al. Free fatty acids induce peripheral insulin resistance without increasing muscle hexosamine pathway product levels in rats. , 2001, Diabetes.
[48] G. Striker. Glucose toxicity. , 2001, Kidney international.
[49] I. G. Fantus,et al. Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[50] I. G. Fantus,et al. Overexpression of GFAT activates PAI-1 promoter in mesangial cells. , 2000, American journal of physiology. Renal physiology.
[51] M. Buse,et al. High glucose and glucosamine induce insulin resistance via different mechanisms in 3T3-L1 adipocytes. , 2000, Diabetes.
[52] L. Rossetti. Perspective: Hexosamines and nutrient sensing. , 2000, Endocrinology.
[53] E. Bonora,et al. Effects of glucosamine infusion on insulin secretion and insulin action in humans. , 2000, Diabetes.
[54] G. Cartee,et al. Lower calorie intake enhances muscle insulin action and reduces hexosamine levels. , 2000, American journal of physiology. Regulatory, integrative and comparative physiology.
[55] G. Shulman,et al. On Diabetes: Insulin Resistance Cellular Mechanisms of Insulin Resistance , 2022 .
[56] A. Saltiel,et al. Signaling pathways in insulin action: molecular targets of insulin resistance. , 2000, The Journal of clinical investigation.
[57] Khan,et al. Arachidonic acid metabolites alter G protein-mediated signal transduction in heart. Effects on muscarinic K+ channels , 1990, The Journal of general physiology.
[58] G. Hart,et al. Regulation of a Cytosolic and Nuclear O-GlcNAc Transferase , 1999, The Journal of Biological Chemistry.
[59] C. Kahn,et al. Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance of early postreceptor insulin signaling events in skeletal muscle. , 1999, Diabetes.
[60] H. Yki-Järvinen,et al. Allosteric regulation of glycogen synthase and hexokinase by glucosamine-6-phosphate during glucosamine-induced insulin resistance in skeletal muscle and heart. , 1999, Diabetes.
[61] N. Ruderman,et al. Hyperglycemia inhibits insulin activation of Akt/protein kinase B but not phosphatidylinositol 3-kinase in rat skeletal muscle. , 1999, Diabetes.
[62] M. Buse,et al. Decreased hexosamine biosynthesis in GH-deficient dwarf rat muscle. Reversal with GH, but not IGF-I, therapy. , 1999, American journal of physiology. Endocrinology and metabolism.
[63] R. Cooksey,et al. Printed in U.S.A. Copyright © 1999 by The Endocrine Society Mechanism of Hexosamine-Induced Insulin Resistance in Transgenic Mice Overexpressing Glutamine:Fructose-6- Phosphate Amidotransferase: Decreased Glucose Transporter GLUT4 Translocation and Revers , 2022 .
[64] H. Heimberg,et al. Glucosamine-induced Insulin Resistance in 3T3-L1 Adipocytes Is Caused by Depletion of Intracellular ATP* , 1998, The Journal of Biological Chemistry.
[65] D. Vaughan,et al. Sp1 Sites Mediate Activation of the Plasminogen Activator Inhibitor-1 Promoter by Glucose in Vascular Smooth Muscle Cells* , 1998, The Journal of Biological Chemistry.
[66] D. McClain,et al. Insulin and glucosamine infusions increase O-linked N-acetyl-glucosamine in skeletal muscle proteins in vivo. , 1998, Metabolism: clinical and experimental.
[67] R. Haltiwanger,et al. Modulation of O-LinkedN-Acetylglucosamine Levels on Nuclear and Cytoplasmic Proteins in Vivo Using the PeptideO-GlcNAc-β-N-acetylglucosaminidase InhibitorO-(2-Acetamido-2-deoxy-dglucopyranosylidene)amino-N-phenylcarbamate* , 1998, The Journal of Biological Chemistry.
[68] U. Sauer,et al. High glucose-induced transforming growth factor beta1 production is mediated by the hexosamine pathway in porcine glomerular mesangial cells. , 1998, The Journal of clinical investigation.
[69] J. E. Kudlow,et al. O glycosylation of an Sp1-derived peptide blocks known Sp1 protein interactions , 1997, Molecular and cellular biology.
[70] M. Buse,et al. Increased activity of the hexosamine synthesis pathway in muscles of insulin-resistant ob/ob mice. , 1997, The American journal of physiology.
[71] I. Han,et al. Reduced O glycosylation of Sp1 is associated with increased proteasome susceptibility , 1997, Molecular and cellular biology.
[72] Wei Chen,et al. Role of the glucosamine pathway in fat-induced insulin resistance. , 1997, The Journal of clinical investigation.
[73] J. Hanover,et al. O-Linked GlcNAc Transferase Is a Conserved Nucleocytoplasmic Protein Containing Tetratricopeptide Repeats* , 1997, The Journal of Biological Chemistry.
[74] G. Hart,et al. Dynamic Glycosylation of Nuclear and Cytosolic Proteins , 1997, The Journal of Biological Chemistry.
[75] M. Williams,et al. Development of Insulin Resistance in 3T3-L1 Adipocytes* , 1997, The Journal of Biological Chemistry.
[76] N. Barzilai,et al. The Tissue Concentration of UDP-N-acetylglucosamine Modulates the Stimulatory Effect of Insulin on Skeletal Muscle Glucose Uptake* , 1997, The Journal of Biological Chemistry.
[77] M. Mueckler,et al. Differential Effects of GLUT1 or GLUT4 Overexpression on Hexosamine Biosynthesis by Muscles of Transgenic Mice* , 1996, The Journal of Biological Chemistry.
[78] D. McClain,et al. Overexpression of glutamine:fructose-6-phosphate amidotransferase in transgenic mice leads to insulin resistance. , 1996, The Journal of clinical investigation.
[79] R. DeFronzo,et al. Increased Glutamine:Fructose-6-Phosphate Amidotransferase Activity in Skeletal Muscle of Patients With NIDDM , 1996, Diabetes.
[80] M. Buse,et al. Effects of Diabetes and Hyperglycemia on the Hexosamine Synthesis Pathway in Rat Muscle and Liver , 1995, Diabetes.
[81] A. Baron,et al. Glucosamine induces insulin resistance in vivo by affecting GLUT 4 translocation in skeletal muscle. Implications for glucose toxicity. , 1995, The Journal of clinical investigation.
[82] Wei Chen,et al. In vivo glucosamine infusion induces insulin resistance in normoglycemic but not in hyperglycemic conscious rats. , 1995, The Journal of clinical investigation.
[83] M. Mueckler,et al. Glucose transport activity in skeletal muscles from transgenic mice overexpressing GLUT1. Increased basal transport is associated with a defective response to diverse stimuli that activate GLUT4. , 1994, The Journal of biological chemistry.
[84] K. Sharma,et al. Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor-beta. , 1994, The Journal of clinical investigation.
[85] M. Buse,et al. Pre-Exposure to Glucosamine Induces Insulin Resistance of Glucose Transport and Glycogen Synthesis in Isolated Rat Skeletal Muscles: Study of Mechanisms in Muscle and in Rat-1 Fibroblasts Overexpressing the Human Insulin Receptor , 1993, Diabetes.
[86] A. Paterson,et al. Glucose and glucosamine regulate growth factor gene expression in vascular smooth muscle cells. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[87] S. Marshall,et al. Discovery of a metabolic pathway mediating glucose-induced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance. , 1991, The Journal of biological chemistry.
[88] A. Krolewski,et al. Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents. , 1990, Annals of internal medicine.
[89] H. Yki-Järvinen,et al. Hyperglycemia Decreases Glucose Uptake in Type I Diabetes , 1987, Diabetes.
[90] S. Steiner. The Mexican Americans , 1979 .