Thermal biosensors in biotechnology.

The application of enzyme thermistor devices for the continuous monitoring of enzymatic processes is described. Different hardware concepts are presented and discussed, practical results are also given. These devices were used to analyze the enantiomeric excess in biotransformation processes and for thermal immunoanalysis. In addition, the biosensors were applied for the monitoring and control of an L-ornithine producing process and for the application in hemodialysis monitoring. A review section discusses the use of thermal biosensors for monitoring biotechnological processes in general.

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