Conversion of ICRP male reference phantom to polygon-surface phantom

The International Commission on Radiological Protection (ICRP) reference phantoms, developed based on computed tomography images of human bodies, provide much more realism of human anatomy than the previously used MIRD5 (Medical Internal Radiation Dose) mathematical phantoms. It has been, however, realized that the ICRP reference phantoms have some critical limitations showing a considerable amount of holes for the skin and wall organs mainly due to the nature of voxels of which the phantoms are made, especially due to their low voxel resolutions. To address this problem, we are planning to develop the polygon-surface version of ICRP reference phantoms by directly converting the ICRP reference phantoms (voxel phantoms) to polygon-surface phantoms. The objective of this preliminary study is to see if it is indeed possible to construct the high-quality polygon-surface phantoms based on the ICRP reference phantoms maintaining identical organ morphology and also to identify any potential issues, and technologies to address these issues, in advance. For this purpose, in the present study, the ICRP reference male phantom was roughly converted to a polygon-surface phantom. Then, the constructed phantom was implemented in Geant4, Monte Carlo particle transport code, for dose calculations, and the calculated dose values were compared with those of the original ICRP reference phantom to see how much the calculated dose values are sensitive to the accuracy of the conversion process. The results of the present study show that it is certainly possible to convert the ICRP reference phantoms to surface phantoms with enough accuracy. In spite of using relatively less resources (<2 man-months), we were able to construct the polygon-surface phantom with the organ masses perfectly matching the ICRP reference values. The analysis of the calculated dose values also implies that the dose values are indeed not very sensitive to the detailed morphology of the organ models in the phantom for highly penetrating radiations such as photons and neutrons. The results of the electron beams, on the other hand, show that the dose values of the polygon-surface phantom are higher by a factor of 2-5 times than those of the ICRP reference phantom for the skin and wall organs which have large holes due to low voxel resolution. The results demonstrate that the ICRP reference phantom could provide significantly unreasonable dose values to thin or wall organs especially for weakly penetrating radiations. Therefore, when compared to the original ICRP reference phantoms, it is believed that the polygon-surface version of ICRP reference phantoms properly developed will not only provide the same or similar dose values (say, difference <5 or 10%) for highly penetrating radiations, but also provide correct dose values for the weakly penetrating radiations such as electrons and other charged particles.

[1]  H. Kawamura,et al.  Introduction to the ICRP Publication 70, “Basic Anatomical and Physiological Data for Use in Radiological Protection: The Skeleton” , 1996 .

[2]  Keith F. Eckerman,et al.  GSF male and female adult voxel models representing ICRP reference man-The present status , 2005 .

[3]  N Petoussi-Henss,et al.  Organ dose conversion coefficients for voxel models of the reference male and female from idealized photon exposures , 2007, Physics in medicine and biology.

[4]  Deanna Hasenauer,et al.  Hybrid computational phantoms of the male and female newborn patient: NURBS-based whole-body models , 2007, Physics in medicine and biology.

[5]  James A. Scott Photon, Electron, Proton and Neutron Interaction Data for Body Tissues ICRU Report 46. International Commission on Radiation Units and Measurements, Bethesda, 1992, $40.00 , 1993 .

[6]  J. Valentin Basic anatomical and physiological data for use in radiological protection: reference values , 2002, Annals of the ICRP.

[7]  Maria Zankl,et al.  Adult Male and Female Reference Computational Phantoms (ICRP Publication 110) , 2010 .

[8]  C. Potter ICRP Publication 100 Human Alimentary Tract Model for Radiological Protection. , 2007 .

[9]  J. W. Vieira,et al.  FASH and MASH: female and male adult human phantoms based on polygon mesh surfaces: II. Dosimetric calculations , 2010, Physics in medicine and biology.

[10]  X. Xu,et al.  RPI-AM and RPI-AF, a pair of mesh-based, size-adjustable adult male and female computational phantoms using ICRP-89 parameters and their calculations for organ doses from monoenergetic photon beams , 2009, Physics in medicine and biology.

[11]  Chan Hyeong Kim,et al.  A polygon-surface reference Korean male phantom (PSRK-Man) and its direct implementation in Geant4 Monte Carlo simulation , 2011, Physics in medicine and biology.

[12]  Reinhard Klein,et al.  Shape retrieval using 3D Zernike descriptors , 2004, Comput. Aided Des..

[13]  Daniel Lodwick,et al.  HYBRID COMPUTATIONAL PHANTOMS REPRESENTING THE REFERENCE ADULT MALE AND ADULT FEMALE: CONSTRUCTION AND APPLICATIONS FOR RETROSPECTIVE DOSIMETRY , 2012, Health physics.

[14]  Jack Valentin,et al.  The 2007 Recommendations of the International Commission on Radiological Protection. ICRP publication 103. , 2007, Annals of the ICRP.

[15]  N Petoussi-Henss,et al.  Conversion Coefficients for Radiological Protection Quantities for External Radiation Exposures , 2010, Annals of the ICRP.

[16]  R. Sievert,et al.  Book Reviews : Recommendations of the International Commission on Radiological Protection (as amended 1959 and revised 1962). I.C.R.P. Publication 6. 70 pp. PERGAMON PRESS. Oxford, London and New York, 1964. £1 5s. 0d. [TB/54] , 1964 .

[17]  Paola Coan,et al.  X-ray phase-contrast imaging: from pre-clinical applications towards clinics , 2013, Physics in medicine and biology.

[18]  V F Cassola,et al.  FASH and MASH: female and male adult human phantoms based on polygon mesh surfaces: I. Development of the anatomy , 2010, Physics in medicine and biology.