Evidence that CDw108 membrane protein bears the JMH blood group antigen

BACKGROUND: CDw108 is a cluster‐of‐differentiation antigen that resides on a glycosylphosphatidylinositol (GPI)‐linked protein; it has not previously been shown to be expressed on red cells. JMH is a high‐ frequency red cell blood group antigen that resides on a GPI‐linked protein of molecular weight similar to that bearing CDw108. The purpose of this study was to investigate whether CDw108 is expressed on red cells and whether it resides on the same membrane protein as does JMH.

[1]  D. Anstee,et al.  Use of the MAIEA Technique to Confirm the Relationship between the Cromer Antigens and Decay‐Accelerating Factor and to Assign Provisionally Antigens to the Short‐Consensus Repeats , 1993, Vox sanguinis.

[2]  Peter D. Issitt,et al.  Applied Blood Group Serology , 1985 .

[3]  B. Haynes,et al.  Human erythrocyte antigens: II. The In(Lu) gene regulates expression of an antigen on an 80-kilodalton protein of human erythrocytes. , 1984, Blood.

[4]  R. Knowles,et al.  FURTHER ANALYSIS OF THE MONOCLONAL ANTIOBODY H8 DEMONSTRATING A JMH‐RELATED SPECIFICITY , 1983, Journal of immunogenetics.

[5]  R. Knowles,et al.  A MONOCLONAL ANTIBODY TO THE HIGH FREQUENCY RED CELL ANTIGEN JMH , 1982, Journal of immunogenetics.

[6]  H. Towbin,et al.  Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[7]  U. K. Laemmli,et al.  Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.

[8]  B. Davis,et al.  Direct implantation and serial transplantation of human acute lymphoblastic leukemia in hamsters, SB-2. , 1968, Cancer research.

[9]  Wim Timens,et al.  Leucocyte typing V. White cell differentiation antigens , 1995 .

[10]  A. Petty Monoclonal antibody-specific immobilisation of erythrocyte antigens (MAIEA). A new technique to selectively determine antigenic sites on red cell membranes. , 1993, Journal of immunological methods.

[11]  P. Lachmann,et al.  Membrane defence against complement lysis: The structure and biological properties of CD59 , 1993, Immunologic research.

[12]  M. Telen,et al.  Isolation of the JMH antigen on a novel phosphatidylinositol-linked human membrane protein. , 1992, Blood.

[13]  M. Telen,et al.  Human erythrocyte antigens. III. Characterization of a panel of murine monoclonal antibodies that react with human erythrocyte and erythroid precursor membranes. , 1987, Vox sanguinis.

[14]  M. Telen,et al.  The acetylcholinesterase defect in paroxysmal nocturnal hemoglobinuria: evidence that the enzyme is absent from the cell membrane. , 1985, Blood.

[15]  J. Dodge,et al.  The preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes. , 1963, Archives of biochemistry and biophysics.