Effects of Osmotic Changes on Measuring Relative Blood Volume: Comparison of Three Hemodialysis Devices.

Recording the relative blood volume is a standard feature of modern dialysis devices. Three different measurement systems are incorporated in currently available dialysis machines. The Gambro-Hospal group and Nikkiso feature blood volume monitors based on different optical methods. The Fresenius Medical Care machines perform blood volume monitoring with an ultrasonic method. On grounds of clinical evidence suggesting a malfunction of the optical methods in the presence of sodium changes, we compared these three systems. Under the tested conditions, both optical systems show opposite and nonplausible courses of blood volume changes. The ultrasonic system seems to be less susceptible to osmotic changes.

[1]  D. Schneditz,et al.  Sensitivity of Hematocrit to Osmotic Effects Induced by Changes in Dialysate Conductivity: Implications for Relative Blood Volume Measurement and Control , 2015, ASAIO journal.

[2]  J. Kron,et al.  Effects of Sodium on Measuring Relative Blood Volume During Hemodialysis Differ by Techniques , 2013, ASAIO journal.

[3]  K. Tabei,et al.  A New Device to Monitor Blood Volume in Hemodialysis Patients , 2010, Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.

[4]  B. Béné,et al.  Analysis of the optical concentration curve to detect access recirculation. , 2006, Kidney international.

[5]  E. Mancini,et al.  Blood volume monitoring and control. , 1996, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[6]  M Spongano,et al.  Continuous on-line optical absorbance recording of blood volume changes during hemodialysis. , 2008, Artificial organs.

[7]  J. Horina,et al.  A blood protein monitor for the continuous measurement of blood volume changes during hemodialysis. , 1990, Kidney international.

[8]  J. Wilkinson,et al.  Dialysis-induced change in erythrocyte volume: effect on change in blood volume calculated from packed cell volume. , 1988, Clinical nephrology.