Impact of endoscopic surgery for an uncommon liposarcoma of the posterior wall of the oropharynx: a case report

For citation purposes: Yoshii R, Yokoyama J, Ohba S, Fujimaki M, Anzai T, Ito S, et al. Impact of endoscopic surgery for an uncommon liposarcoma of the posterior wall of the oropharynx: a case report. Head Neck Oncol. 2012 Sep 9;4(2):63. Copyright © 2012 OA Publishing London Abstract Introduction The majority of liposarcoma arise in the lower extremities; however, the incidence of liposarcoma of the oro­ pharynx is extremely rare. We report a case of oropharyngeal liposarcoma that was successfully resected with an endoscope. Case A 48-year-old female with dyspnoea was referred to our hospital. We found a tumour that originated from the oropharyngeal posterior wall and extended to the hypopharynx. The tumour sometimes obstructed the aditus of the larynx; therefore, the patient had persistent discomfort be­ cause of the tumour. In order to main­ tain the oropharyngeal functions and for cosmetic purposes, the tumour was resected transorally with a con­ stricted pharyngeal muscle using an endoscope, and the surgical defect resulted in naked pre-vertebral fas­ cia. The defect was reconstructed with poly glycolic acid sheets. The pa­ tient could consume soft food on the first post-operative day and normal food on the fifth day. Conclusion An uncommon liposarcoma from the oropharynx extending to the hypo­ pharynx was safely resected trans­ orally with an endoscope, with preservation of good post-operative function and appearance.

[1]  G. Kawasaki,et al.  Polyglycolic acid sheets with fibrin glue (MCFP technique) for resection of oral mucosa. , 2012, The British journal of oral & maxillofacial surgery.

[2]  A. Gammoudi,et al.  Head and neck liposarcomas: a 32 years experience. , 2010, Auris, nasus, larynx.

[3]  H. Itano.  The optimal technique for combined application of fibrin sealant and bioabsorbable felt against alveolar air leakage. , 2008, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[4]  E. Yu,et al.  Nasopharyngeal liposarcoma MRI imaging features and a review of the literature. , 2007, The British journal of radiology.

[5]  I. Allon,et al.  Liposarcoma of the tongue: clinico-pathologic correlations of a possible underdiagnosed entity. , 2005, Oral oncology.

[6]  L. Bemis,et al.  C-kit expression in dedifferentiated and well-differentiated liposarcomas; immunohistochemistry and genetic analysis. , 2005, Anticancer research.

[7]  C. Helms,et al.  Lipomas, lipoma variants, and well-differentiated liposarcomas (atypical lipomas): results of MRI evaluations of 126 consecutive fatty masses. , 2004, AJR. American journal of roentgenology.

[8]  M. Wax,et al.  Swallowing Function and Tracheotomy Dependence After Combined‐Modality Treatment Including Free Tissue Transfer for Advanced‐Stage Oropharyngeal Cancer , 2003, The Laryngoscope.

[9]  W. Peh.  Soft-tissue tumor. , 2000, American journal of orthopedics.

[10]  P. D. Dal Cin,et al.  Coordinated expression and amplification of the MDM2, CDK4, and HMGI‐C genes in atypical lipomatous tumours , 2000, The Journal of pathology.

[11]  R. Paczona,et al.  Review of the Literature and Report of Two Cases , 1999, The Annals of otology, rhinology, and laryngology.

[12]  P. Mouret.  Liposarcoma of the hypopharynx. A case report and review of the literature. , 1999, Revue de laryngologie - otologie - rhinologie.

[13]  B. Rodgers,et al.  Well-differentiated liposarcoma of the hypopharynx , 1998, The Journal of Laryngology & Otology.

[14]  N. Wambeek,et al.  Liposarcoma of the hypopharynx. , 1996, Australasian radiology.

[15]  J. Reed,et al.  Hypopharyngeal Liposarcoma , 1996, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[16]  D. Oldring,et al.  Liposarcoma of the base of tongue and tonsillar fossa: A possibly underdiagnosed neoplasm. , 1996, Archives of pathology & laboratory medicine.

[17]  C. Fisher,et al.  Head and neck liposarcoma , 1995, Cancer.

[18]  B. Wenig,et al.  Liposarcomas of the larynx and hypopharynx: A clinicopathologic study of eight new cases and a review of the literature , 1995, The Laryngoscope.

[19]  M. Feinmesser,et al.  Liposarcoma of the nasopharynx: a case report. , 1991, Ear, nose, & throat journal.

[20]  B. Wenig,et al.  Laryngeal and Hypopharyngeal Liposarcoma A Clinicopathologic Study of 10 Cases with a Comparison to Soft‐Tissue Counterparts , 1990, The American journal of surgical pathology.

[21]  E. Baden,et al.  Liposarcoma of the oropharyngeal region. Review of the literature and report of two cases. , 1977, Oral surgery, oral medicine, and oral pathology.

[22]  H. Suit,et al.  A clinical and pathological staging system for soft tissue sarcomas , 1977, Cancer.