Tracing cellular heterogeneity in pooled genetic screens via multi-level barcoding

[1]  Ruth E Hanna,et al.  A case of mistaken identity , 2018, Nature Biotechnology.

[2]  Mudra Hegde,et al.  Uncoupling of sgRNAs from their associated barcodes during PCR amplification of combinatorial CRISPR screens , 2018, bioRxiv.

[3]  Michael T. McManus,et al.  Dual gene activation and knockout screen reveals directional dependencies in genetic networks , 2018, Nature Biotechnology.

[4]  John G Doench,et al.  Am I ready for CRISPR? A user's guide to genetic screens , 2017, Nature Reviews Genetics.

[5]  R. Nitsch,et al.  CRISPR-UMI: single-cell lineage tracing of pooled CRISPR–Cas9 screens , 2017, Nature Methods.

[6]  J. Taipale,et al.  CRISPR/Cas9 screening using unique molecular identifiers , 2017, bioRxiv.

[7]  R. Bernards,et al.  CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes , 2016, Nature Biotechnology.

[8]  A. Weiss,et al.  A CRISPR-Based Toolbox for Studying T Cell Signal Transduction , 2016, BioMed research international.

[9]  Michael T. McManus,et al.  Choosing the Right Tool for the Job: RNAi, TALEN, or CRISPR. , 2015, Molecular cell.

[10]  Neville E. Sanjana,et al.  High-throughput functional genomics using CRISPR–Cas9 , 2015, Nature Reviews Genetics.

[11]  Jun S. Liu,et al.  MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens , 2014, Genome Biology.

[12]  Max A. Horlbeck,et al.  Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation , 2014, Cell.

[13]  Shiyou Zhu,et al.  High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells , 2014, Nature.

[14]  Yilong Li,et al.  Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library , 2013, Nature Biotechnology.

[15]  E. Lander,et al.  Genetic Screens in Human Cells Using the CRISPR-Cas9 System , 2013, Science.

[16]  Lani F. Wu,et al.  Cellular Heterogeneity: Do Differences Make a Difference? , 2010, Cell.

[17]  S. Wang,et al.  The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway , 2008, Oncogene.

[18]  Kenneth M. Yamada Signal transduction , 2004, Definitions.