Improving lesion localization when imaging with handheld reflectance confocal microscope

• The handheld reflectance confocal microscope facilitates the rapid imaging of skin lesions and is well suited for imaging on curved anatomical sites. However, maintaining the position of the 1 mm probe can be difficult. To address this, we began using adhesive paper rings with different diameters centered over the areas of interest. The ring fibers are readily distinguished from skin, thus serving as a reference frame and ensuring the correct positioning of the device.