Altered Interatrial Conduction Detected in MADIT II Patients Bound to Develop Atrial Fibrillation

Background: Changes in P‐wave morphology have recently been shown to be associated with interatrial conduction route used, without noticeable changes of P‐wave duration. This study aimed at exploring the association between P‐wave morphology and future atrial fibrillation (AF) development in the Multicenter Automatic Defibrillator Trial II (MADIT II) population.

[1]  M Fukunami,et al.  Detection of Patients at Risk for Paroxysmal Atrial Fibrillation During Sinus Rhythm by P Wave‐Triggered Signal‐Averaged Electrocardiogram , 1991, Circulation.

[2]  Robert Lemery,et al.  Human Study of Biatrial Electrical Coupling: Determinants of Endocardial Septal Activation and Conduction Over Interatrial Connections , 2004, Circulation.

[3]  M Fukunami,et al.  Characteristics of frequency content of atrial signal-averaged electrocardiograms during sinus rhythm in patients with paroxysmal atrial fibrillation. , 1992, Journal of the American College of Cardiology.

[4]  V Hombach,et al.  Standards for analysis of ventricular late potentials using high-resolution or signal-averaged electrocardiography: a statement by a task force committee of the European Society of Cardiology, the American Heart Association, and the American College of Cardiology. , 1991, Journal of the American College of Cardiology.

[5]  S. Zelenkofske,et al.  Value of the P‐Wave Signal‐Averaged ECG for Predicting Atrial Fibrillation After Cardiac Surgery , 1993, Circulation.

[6]  W. Aronow,et al.  Association of interatrial block with development of atrial fibrillation. , 2003, The American journal of cardiology.

[7]  F. Cosío,et al.  Atrial Activation Mapping in Sinus Rhythm in the Clinical Electrophysiology Laboratory: , 2004, Journal of cardiovascular electrophysiology.

[8]  J. Steinberg,et al.  Value of the signal-averaged P wave analysis in predicting atrial fibrillation after cardiac surgery. , 1998, Journal of electrocardiology.

[9]  M. Allessie,et al.  High-density mapping of electrically induced atrial fibrillation in humans. , 1994, Circulation.

[10]  Lauri Toivonen,et al.  Interatrial conduction can be accurately determined using standard 12-lead electrocardiography: validation of P-wave morphology using electroanatomic mapping in man. , 2008, Heart rhythm.

[11]  A. Bayés‐Genís,et al.  Third-degree inter-atrial block and supraventricular tachyarrhythmias. , 1999, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[12]  S H Lee,et al.  Reversal of atrial electrical remodeling following cardioversion of long-standing atrial fibrillation in man. , 1999, Cardiovascular research.

[13]  H. Thompson,et al.  P‐Wave Analysis in Valvular Heart Disease , 1963, Circulation.

[14]  S. Ho,et al.  Electroanatomic Analysis of Sinus Impulse Propagation in Normal Human Atria , 2002, Journal of cardiovascular electrophysiology.

[15]  P A Wolf,et al.  Prevalence, incidence, prognosis, and predisposing conditions for atrial fibrillation: population-based estimates. , 1998, The American journal of cardiology.

[16]  K. Forfang,et al.  P wave terminal force and persisting ST elevations in chronic ischemic heart disease. Prediciton of left ventricular motility and diastolic pressure. , 1976, American heart journal.

[17]  Alberto Herreros,et al.  Age-related changes in P wave morphology in healthy subjects , 2007, BMC cardiovascular disorders.

[18]  J. Oss,et al.  PROPHYLACTIC IMPLANTATION OF A DEFIBRILLATOR IN PATIENTS WITH MYOCARDIAL INFARCTION AND REDUCED EJECTION FRACTION , 2002 .

[19]  M. Allessie,et al.  Atrial fibrillation begets atrial fibrillation. A study in awake chronically instrumented goats. , 1995, Circulation.

[20]  Hugh Calkins,et al.  Symptomatic and Asymptomatic Atrial Fibrillation in Patients Undergoing Radiofrequency Catheter Ablation , 2006, Journal of cardiovascular electrophysiology.

[21]  Douglas L. Jones,et al.  Chronic rapid atrial pacing. Structural, functional, and electrophysiological characteristics of a new model of sustained atrial fibrillation. , 1995, Circulation.

[22]  Jonas Carlson,et al.  Signal-averaged P wave analysis for delineation of interatrial conduction – Further validation of the method , 2007, BMC cardiovascular disorders.

[23]  A. De Simone,et al.  Role of transtelephonic electrocardiographic monitoring in detecting short-term arrhythmia recurrences after radiofrequency ablation in patients with atrial fibrillation. , 2005, Journal of the American College of Cardiology.

[24]  S. Olsson,et al.  Variable Interatrial Conduction Illustrated in a Hypertrophic Cardiomyopathy Population , 2006, Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.

[25]  Nicholas S. Peters,et al.  Characterization of Left Atrial Activation in the Intact Human Heart , 2003, Circulation.

[26]  D. Spodick,et al.  Interatrial block: pandemic prevalence, significance, and diagnosis. , 2005, Chest.

[27]  A Hansson,et al.  Detection of inter-atrial conduction defects with unfiltered signal-averaged P-wave ECG in patients with lone atrial fibrillation. , 2000, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[28]  A. Bayés de Luna,et al.  Interatrial conduction block and retrograde activation of the left atrium and paroxysmal supraventricular tachyarrhythmia. , 1988, European heart journal.

[29]  Alberto Herreros,et al.  Exploration of Supraventricular Conduction with respect to Atrial Fibrillation. Methodological Aspects on Selected Techniques , 2005 .

[30]  C. Pandozi,et al.  Electrophysiological characteristics of the human atria after cardioversion of persistent atrial fibrillation. , 1998, Circulation.

[31]  A. Bayés de Luna,et al.  Electrocardiographic and vectorcardiographic study of interatrial conduction disturbances with left atrial retrograde activation. , 1985, Journal of electrocardiology.