Development of new quantitative mass spectrometry and semi-automatic isofocusing methods for the determination of Apolipoprotein E typing.

[1]  GaratacheaNuria,et al.  The ApoE gene is related with exceptional longevity: a systematic review and meta-analysis. , 2015 .

[2]  R. Mahley,et al.  Apolipoprotein E: Structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases , 2014, Neurobiology of Disease.

[3]  S. Lehmann,et al.  Clinical measurement of Hepcidin-25 in human serum: Is quantitative mass spectrometry up to the job? , 2014 .

[4]  Cheng-Hsien Lu,et al.  The Association between Serological Biomarkers and Primary Sjogren's Syndrome Associated with Peripheral Polyneuropathy , 2014, BioMed research international.

[5]  K. Matsushita,et al.  Human Apolipoprotein E Resequencing by Proteomic Analysis and Its Application to Serotyping , 2014, PloS one.

[6]  D. Hochstrasser,et al.  Quantitative Clinical Chemistry Proteomics (qCCP) using mass spectrometry: general characteristics and application , 2013, Clinical chemistry and laboratory medicine.

[7]  J. Lambert,et al.  Total ApoE and ApoE4 Isoform Assays in an Alzheimer's Disease Case-control Study by Targeted Mass Spectrometry (n = 669): A Pilot Assay for Methionine-containing Proteotypic Peptides* , 2012, Molecular & Cellular Proteomics.

[8]  Guojun Bu,et al.  Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease. , 2012, Cold Spring Harbor perspectives in medicine.

[9]  P. Bosco,et al.  APOE and Alzheimer disease: a major gene with semi-dominant inheritance , 2011, Molecular Psychiatry.

[10]  R. Bateman,et al.  Method for the simultaneous quantitation of apolipoprotein E isoforms using tandem mass spectrometry. , 2009, Analytical biochemistry.

[11]  E. Souied,et al.  PLEKHA1-LOC387715-HTRA1 polymorphisms and exudative age-related macular degeneration in the French population. , 2007, Molecular vision.

[12]  Mu Wang,et al.  A multiple reaction monitoring method for absolute quantification of the human liver alcohol dehydrogenase ADH1C1 isoenzyme. , 2007, Analytical biochemistry.

[13]  Bernard Keavney,et al.  Association of apolipoprotein E genotypes with lipid levels and coronary risk. , 2007, JAMA.

[14]  R. Mahley,et al.  Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[15]  M. Krempf,et al.  Intronic mutations outside of Alu-repeat-rich domains of the LDL receptor gene are a cause of familial hypercholesterolemia , 2002, Human Genetics.

[16]  Miguel Ángel Martínez,et al.  Apolipoprotein E and Alzheimer disease: genotype-specific risks by age and sex. , 1997, American journal of human genetics.

[17]  P. Wilson,et al.  Frequency of phenotype-genotype discrepancies at the apolipoprotein E locus in a large population study. , 1996, Clinical chemistry.

[18]  F. Muskiet,et al.  Clinical chemistry of common apolipoprotein E isoforms. , 1996, Journal of chromatography. B, Biomedical applications.

[19]  S. Humphries,et al.  High-throughput method for determination of apolipoprotein E genotypes with use of restriction digestion analysis by microplate array diagonal gel electrophoresis. , 1995, Clinical chemistry.

[20]  A D Roses,et al.  Apolipoprotein E and Alzheimer disease. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[21]  M. Tuchman,et al.  Determination of apolipoprotein E genotypes by single-strand conformational polymorphism. , 1993, Clinical chemistry.

[22]  J. Sertić,et al.  Apolipoprotein E phenotypes and genotypes as determined by polymerase chain reaction using allele-specific oligonucleotide probes and the amplification refractory mutation system in children with insulin-dependent diabetes mellitus. , 1993, Clinica chimica acta; international journal of clinical chemistry.

[23]  T. Teramoto,et al.  Determination by PCR-RFLP of apo E genotype in a Japanese population. , 1993, The Journal of laboratory and clinical medicine.

[24]  A. Sedky,et al.  Apolipoprotein E Phenotyping: A Word of Caution , 1991, Annals of clinical biochemistry.

[25]  S. Humphries,et al.  Disparity between apolipoprotein E phenotypes and genotypes (as determined by polymerase chain reaction and oligonucleotide probes) in patients with non-insulin-dependent diabetes mellitus. , 1991, Clinica chimica acta; international journal of clinical chemistry.

[26]  A. Syvänen,et al.  Apolipoprotein E polymorphism determined by restriction enzyme analysis of DNA amplified by polymerase chain reaction: convenient alternative to phenotyping by isoelectric focusing. , 1990, Clinical chemistry.

[27]  R. Mahley,et al.  Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. , 1988, Science.

[28]  Johannes Kornhuber,et al.  APOE-dependent phenotypes in subjects with mild cognitive impairment converting to Alzheimer's disease. , 2013, Journal of Alzheimer's disease : JAD.

[29]  A. D. Roses,et al.  Association of apolipoprotein E allele €4 with late-onset familial and sporadic Alzheimer’s disease , 2006 .

[30]  M A Pericak-Vance,et al.  Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. , 1993, Neurology.

[31]  A. Chakravarti,et al.  Estimation of the frequency of isoform–genotype discrepancies at the apolipoprotein E locus in heterozygotes for the isoforms , 1992, Genetic epidemiology.