Oscillation analysis of linearly coupled piecewise affine systems: Application to spatio-temporal neuron dynamics

This paper discusses oscillation analysis of (a large number of) linearly coupled piecewise affine (PWA) systems, motivated by various kinds of reaction-diffusion systems including cell-signaling dynamics and neural dynamics. We derive a sufficient condition under which the system shows an oscillatory behavior called Y-oscillation. It is known that the analysis of PWA systems is difficult due to their switching nature. An important feature of the result obtained is that, under the assumption that every subsystem has a specific property in common, the criteria can be rewritten in terms of coupling topology in an easily checkable way, so it is applicable to large scale systems. The results obtained are applied to theoretical investigation of the cardiac action potential generation/propagation represented by spatio-temporal FitzHugh-Nagumo equations.

[1]  Kazuyuki Aihara,et al.  Modeling and Analyzing Biological Oscillations in Molecular Networks , 2008, Proceedings of the IEEE.

[2]  Guy-Bart Stan,et al.  Global Asymptotic Stability of the Limit Cycle in Piecewise Linear versions of the Goodwin Oscillator , 2008 .

[3]  Rodolphe Sepulchre,et al.  Analysis of Interconnected Oscillators by Dissipativity Theory , 2007, IEEE Transactions on Automatic Control.

[4]  J. Mallet-Paret,et al.  The Poincare-Bendixson theorem for monotone cyclic feedback systems , 1990 .

[5]  J. Hindmarsh,et al.  A model of neuronal bursting using three coupled first order differential equations , 1984, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[6]  Munther A. Dahleh,et al.  Global analysis of piecewise linear systems using impact maps and surface Lyapunov functions , 2003, IEEE Trans. Autom. Control..

[7]  J. NAGUMOt,et al.  An Active Pulse Transmission Line Simulating Nerve Axon , 2006 .

[8]  順一 井村,et al.  Nonlinear Systems Third Edition, Hassan K. Khalil著, 出版社 Prentice Hall, 発行 2002年, 全ページ 750頁, 価格 £39.99, ISBN 0-13-067389-7 , 2003 .

[9]  L. Chua,et al.  Synchronization in an array of linearly coupled dynamical systems , 1995 .

[10]  David Angeli,et al.  Oscillations in I/O Monotone Systems Under Negative Feedback , 2007, IEEE Transactions on Automatic Control.

[11]  Denis V. Efimov,et al.  Oscillatority of Nonlinear Systems with Static Feedback , 2009, SIAM J. Control. Optim..

[12]  G. Sell,et al.  THE POINCARE-BENDIXSON THEOREM FOR MONOTONE CYCLIC FEEDBACK SYSTEMS WITH DELAY , 1996 .

[13]  Leon O. Chua,et al.  The Hopf bifurcation theorem and its applications to nonlinear oscillations in circuits and systems , 1979 .

[14]  Frank Allgöwer,et al.  Delay robustness in consensus problems , 2010, Autom..

[15]  John Crank,et al.  The Mathematics Of Diffusion , 1956 .

[16]  G. Ermentrout,et al.  Coupled oscillators and the design of central pattern generators , 1988 .

[17]  Carroll,et al.  Synchronous chaos in coupled oscillator systems. , 1994, Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics.

[18]  Kenji Kashima,et al.  Piecewise affine systems approach to control of biological networks , 2010, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences.

[19]  J. Dunlap,et al.  Neurospora wc-1 and wc-2: transcription, photoresponses, and the origins of circadian rhythmicity. , 1997, Science.

[20]  A. Goldbeter A model for circadian oscillations in the Drosophila period protein (PER) , 1995, Proceedings of the Royal Society of London. Series B: Biological Sciences.

[21]  A. M. Turing,et al.  The chemical basis of morphogenesis , 1952, Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences.

[22]  I. Tyukin,et al.  Semi-passivity and synchronization of diffusively coupled neuronal oscillators , 2009, 0903.3535.

[23]  G. Hu,et al.  Instability and controllability of linearly coupled oscillators: Eigenvalue analysis , 1998 .

[24]  Jun-ichi Imura,et al.  Oscillation analysis of linearly coupled piecewise affine systems , 2010, HSCC '10.

[25]  B. Kholodenko Cell-signalling dynamics in time and space , 2006, Nature Reviews Molecular Cell Biology.

[26]  A. Hodgkin,et al.  A quantitative description of membrane current and its application to conduction and excitation in nerve , 1990 .

[27]  T. Glad,et al.  On Diffusion Driven Oscillations in Coupled Dynamical Systems , 1999 .

[28]  Leon O. Chua,et al.  Autonomous cellular neural networks: a unified paradigm for pattern formation and active wave propagation , 1995 .

[29]  G. Barton The Mathematics of Diffusion 2nd edn , 1975 .

[30]  Mihailo R. Jovanovic,et al.  A Passivity-Based Approach to Stability of Spatially Distributed Systems With a Cyclic Interconnection Structure , 2008, IEEE Transactions on Automatic Control.

[31]  I. Stewart,et al.  Coupled nonlinear oscillators and the symmetries of animal gaits , 1993 .

[32]  James P. Keener,et al.  Mathematical physiology , 1998 .

[33]  H. Nijmeijer,et al.  Cooperative oscillatory behavior of mutually coupled dynamical systems , 2001 .

[34]  Anders Rantzer,et al.  Computation of piecewise quadratic Lyapunov functions for hybrid systems , 1997, 1997 European Control Conference (ECC).