Chlorambucil (nitrogen mustard) induced impairment of early vascular endothelial cell migration - effects of α-linolenic acid and N-acetylcysteine.

[1]  R. Agarwal,et al.  Cutaneous Injury-Related Structural Changes and Their Progression following Topical Nitrogen Mustard Exposure in Hairless and Haired Mice , 2014, PloS one.

[2]  J. Shute,et al.  N-acetyl-L-cysteine protects against inhaled sulfur mustard poisoning in the large swine , 2013, Clinical toxicology.

[3]  S. Jane,et al.  Golgi Feels Its Own Wound. , 2013, Advances in wound care.

[4]  H. Ishida,et al.  Nitric Oxide Synthase Gene Transfer Overcomes the Inhibition of Wound Healing by Sulfur Mustard in a Human Keratinocyte In Vitro Model , 2012, ISRN toxicology.

[5]  T. Kadar,et al.  Characterization of acute and long‐term pathologies of superficial and deep dermal sulfur mustard skin lesions in the hairless guinea pig model , 2012, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

[6]  R. Enzenauer,et al.  Silibinin, dexamethasone, and doxycycline as potential therapeutic agents for treating vesicant-inflicted ocular injuries. , 2012, Toxicology and applied pharmacology.

[7]  J. Schmitt,et al.  Interventions for mycosis fungoides. , 2012, The Cochrane database of systematic reviews.

[8]  Xiang Yan,et al.  Chlorambucil for patients with primary biliary cirrhosis. , 2012, The Cochrane database of systematic reviews.

[9]  R. Houot,et al.  Combination of rituximab, bortezomib, doxorubicin, dexamethasone and chlorambucil (RiPAD+C) as first-line therapy for elderly mantle cell lymphoma patients: results of a phase II trial from the GOELAMS. , 2012, Annals of oncology : official journal of the European Society for Medical Oncology.

[10]  J. Graham,et al.  Metabolic activation of sulfur mustard leads to oxygen free radical formation. , 2012, Free radical biology & medicine.

[11]  G. Dulan,et al.  Regulation of VEGF-induced endothelial cell migration by mitochondrial reactive oxygen species. , 2011, American journal of physiology. Cell physiology.

[12]  W. Bloch,et al.  Effect of N-acetyl cysteine and alpha-linolenic acid on sulfur mustard caused impairment of in vitro endothelial tube formation. , 2010, Toxicological sciences : an official journal of the Society of Toxicology.

[13]  T. S. S. Dikshith Handbook of Chemicals and Safety , 2010 .

[14]  J. Lippincott-Schwartz,et al.  Analysis of Mitochondrial Dynamics and Functions Using Imaging Approaches , 2010, Current protocols in cell biology.

[15]  D. Wathes,et al.  The Effect of Linolenic Acid on Bovine Oocyte Maturation and Development1 , 2009, Biology of reproduction.

[16]  K. Kehe,et al.  Molecular toxicology of sulfur mustard-induced cutaneous inflammation and blistering. , 2009, Toxicology.

[17]  W. Bloch,et al.  Nitrogen mustard (Chlorambucil) has a negative influence on early vascular development. , 2009, Toxicology.

[18]  W. Bloch,et al.  Sulphur mustard induces time- and concentration-dependent regulation of NO-synthesizing enzymes. , 2009, Toxicology letters.

[19]  C. White,et al.  A Role for Mitochondrial Oxidative Stress in Sulfur Mustard Analog 2-Chloroethyl Ethyl Sulfide-Induced Lung Cell Injury and Antioxidant Protection , 2009, Journal of Pharmacology and Experimental Therapeutics.

[20]  W. Stone,et al.  The influence of N-acetyl-L-cysteine on oxidative stress and nitric oxide synthesis in stimulated macrophages treated with a mustard gas analogue , 2008, BMC Cell Biology.

[21]  M. Ghanei,et al.  Therapeutics effect of N-acetyl cysteine on mustard gas exposed patients: evaluating clinical aspect in patients with impaired pulmonary function test. , 2008, Respiratory medicine.

[22]  Z. Suntres,et al.  Sulfur Mustard Toxicity Following Dermal Exposure: Role of Oxidative Stress, and Antioxidant Therapy , 2007 .

[23]  J. Kissil,et al.  Angiomotin regulates endothelial cell migration during embryonic angiogenesis. , 2007, Genes & development.

[24]  Bo Mattiasson,et al.  Methods in cell separations. , 2007, Advances in biochemical engineering/biotechnology.

[25]  Leni Moldovan,et al.  Reactive oxygen species in vascular endothelial cell motility. Roles of NAD(P)H oxidase and Rac1. , 2006, Cardiovascular research.

[26]  R. Dummer,et al.  EORTC consensus recommendations for the treatment of mycosis fungoides/Sézary syndrome. , 2006, European journal of cancer.

[27]  R. Schwinger,et al.  eNOS translocation but not eNOS phosphorylation is dependent on intracellular Ca2+ in human atrial myocardium. , 2006, American journal of physiology. Cell physiology.

[28]  A. Korkmaz,et al.  Molecular targets against mustard toxicity: implication of cell surface receptors, peroxynitrite production, and PARP activation , 2006, Archives of Toxicology.

[29]  R. Schwinger,et al.  Role of erythropoietin for angiogenesis and vasculogenesis: from embryonic development through adulthood. , 2006, American journal of physiology. Heart and circulatory physiology.

[30]  Stephen M Bauer,et al.  Angiogenesis, Vasculogenesis, and Induction of Healing in Chronic Wounds , 2005, Vascular and endovascular surgery.

[31]  T. Mitchison,et al.  A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods , 2004, BMC biotechnology.

[32]  G. Bloom,et al.  IQGAP1, a Novel Vascular Endothelial Growth Factor Receptor Binding Protein, Is Involved in Reactive Oxygen Species–Dependent Endothelial Migration and Proliferation , 2004, Circulation research.

[33]  H. Jaeschke,et al.  Acetaminophen-induced oxidant stress and cell injury in cultured mouse hepatocytes: protection by N-acetyl cysteine. , 2004, Toxicological sciences : an official journal of the Society of Toxicology.

[34]  R. Timpl,et al.  Influence of endostatin on embryonic vasculo‐ and angiogenesis , 2004, Developmental dynamics : an official publication of the American Association of Anatomists.

[35]  M. Martins-Green,et al.  Firsthand cigarette smoke alters fibroblast migration and survival: implications for impaired healing , 2004, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

[36]  Rafael Radi,et al.  Nitric oxide, oxidants, and protein tyrosine nitration , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[37]  P. Gibson,et al.  Biomarkers of lipid peroxidation, airway inflammation and asthma , 2003, European Respiratory Journal.

[38]  P. Rice Sulphur Mustard Injuries of the Skin , 2003, Toxicological reviews.

[39]  K. Schomacker,et al.  Efficacy of laser debridement with autologous split-thickness skin grafting in promoting improved healing of deep cutaneous sulfur mustard burns. , 2002, Burns : journal of the International Society for Burn Injuries.

[40]  D. Hinshaw,et al.  N‐acetylcysteine and endothelial cell injury by sulfur mustard , 2000, Journal of applied toxicology : JAT.

[41]  Timothy C. Marrs,et al.  Chemical Warfare Agents: Toxicology and Treatment , 1996 .

[42]  S. Singer,et al.  Polarization of the Golgi apparatus and the microtubule-organizing center in cultured fibroblasts at the edge of an experimental wound. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[43]  Bierman Hr,et al.  METHYL-BIS (BETA-CHLOROETHYL) AMINE IN LARGE DOSES IN THE TREATMENT OF NEOPLASTIC DISEASES , 1949 .