Numerical simulation of nonlinear feedback model of saccade generation circuit implemented in the LabView graphical programming language

The object-oriented graphical programming language LabView was used to implement the numerical solution to a computational model of saccade generation in primates. The computational model simulates the activity and connectivity of anatomical strictures known to be involved in saccadic eye movements. The LabView program provides a graphical user interface to the model that makes it easy to observe and modify the behavior of each element of the model. Essential elements of the source code of the LabView program are presented and explained. A copy of the model is available for download from the internet.

[1]  C J Kalkman,et al.  LabVIEW: A software system for data acquisition, data analysis, and instrument control , 1995, Journal of clinical monitoring.

[2]  P. Bach-y-Rita,et al.  Basic Mechanisms of Ocular Motility and Their Clinical Implications , 1976 .

[3]  D Guitton,et al.  Analysis of primate IBN spike trains using system identification techniques. I. Relationship To eye movement dynamics during head-fixed saccades. , 1997, Journal of neurophysiology.

[4]  S. Gielen,et al.  A quantitative analysis of generation of saccadic eye movements by burst neurons. , 1981, Journal of neurophysiology.

[5]  L E Mays,et al.  Signal transformations required for the generation of saccadic eye movements. , 1990, Annual review of neuroscience.

[6]  E. Keller.  Participation of medial pontine reticular formation in eye movement generation in monkey. , 1974, Journal of neurophysiology.

[7]  Lance M. Optican,et al.  Superior colliculus cell types and models of saccade generation , 1994, Current Opinion in Neurobiology.

[8]  Michael A. Nordstrom,et al.  Spike-train acquisition, analysis and real-time experimental control using a graphical programming language (LabView®) , 1995, Journal of Neuroscience Methods.

[9]  J H Moore,et al.  Artificial intelligence programming with LabVIEW: genetic algorithms for instrumentation control and optimization. , 1995, Computer methods and programs in biomedicine.

[10]  Ian S. Curthoys,et al.  Direct projection of pause neurons to nystagmus-related excitatory burst neurons in the cat pontine reticular formation , 1984, Experimental Neurology.

[11]  J. Gnadt,et al.  Analysis of the step response of the saccadic feedback: computational models , 1997, Experimental Brain Research.

[12]  Frédéric Gaillard,et al.  Stimulation, data acquisition, spikes detection and time/rate analysis with a graphical programming system: an application to vision studies , 1995, Journal of Neuroscience Methods.

[13]  M. Grossmann,et al.  A simple computer based system to analyze Morris water maze trials on-line , 1996, Journal of Neuroscience Methods.

[14]  C. Scudder,et al.  The microscopic anatomy and physiology of the mammalian saccadic system , 1996, Progress in Neurobiology.