The Protective Effect against E. coli of O and K Antibodies of Different Immunoglobulin Classes

The protective effect of antiserum to E. coli bacteria was studied in intraperitoneally infected mice. It was found that protection was obtained with O and K antibodies. There was no indication that H antibodies could prevent infection. 19S (IgM) and 78 (IgG) antibodies showed about the same protection against infection.

[1]  J. Holmgren,et al.  Characterization of precipitating antibodies to E. coli O antigen in infants and children with acute pyelonephritis. , 1971, Clinical and experimental immunology.

[2]  J. Holmgren,et al.  30. Capsular antibodies to Escherichia coli in relation to urinary trait infectious (UTI) , 1971, Pediatric Research.

[3]  J. G. Michael,et al.  Biological Activities of Rabbit Immunoglobulin M and Immunoglobulin G Antibodies to Pseudomonas aeruginosa , 1970, Infection and immunity.

[4]  J. Holmgren.  The antibody response in rabbits to E. coli O antigen. , 1970, International archives of allergy and applied immunology.

[5]  J. Holmgren.  The antibody response in rabbits to E. coli K antigen. , 1970, International archives of allergy and applied immunology.

[6]  J. Holmgren.  Studies of methods for quantitation of agglutinins and precipitins to Escherichia coli O and K antigens. , 1970, International archives of allergy and applied immunology.

[7]  J. Holmgren,et al.  Immunodiffusion studies on Escherichia coli. 1. Identification of O, K and H antigens in an O6 strain. , 2009, Acta pathologica et microbiologica Scandinavica.

[8]  C. Dewitt,et al.  Mouse Virulence of K(L) Antigen-Containing Strains of Escherichia coli , 1969, Journal of bacteriology.

[9]  H. J. Andersen.  Clinical Studies on the Antibody Response to E. Coli O‐Antigens in Infants and Children with Urinary Tract Infection, Using a Passive Haemagglutination Technique , 1968, Acta paediatrica Scandinavica.

[10]  R. Pike,et al.  Agglutinating and Precipitating Capacity of Rabbit Anti-Salmonella typhosa γG and γM Antibodies During Prolonged Immunization , 1966 .

[11]  A. Monto,et al.  Host-parasite interaction in patients with infections due to Escherichia coli. II. Serologic response of the host. , 1965, Journal of Laboratory and Clinical Medicine.

[12]  J. Williamson,et al.  ANTIBACTERIAL ANTIBODIES IN COLIFORM URINARY TRACT INFECTIONS. , 1964, Archives of internal medicine.

[13]  J. Sanford,et al.  THE ROLE OF IMMUNITY IN THE PATHOGENESIS OF EXPERIMENTAL HEMATOGENOUS PYELONEPHRITIS , 1962, The Journal of experimental medicine.

[14]  F. Ørskov.  Studies on a number of Escherichia coli strains belonging to O group 86. , 2009, Acta pathologica et microbiologica Scandinavica.

[15]  D. Rowley.  The virulence of strains of Bacterium coli for mice. , 1954, British journal of experimental pathology.