Amniotic membrane transplantation for the reconstruction of the ocular surface in three cases.

This paper describes the use of amniotic membrane in the reconstructive surgical repair of generalized keratomalacia, ankyloblepharon, and after fibrous histiocytoma removal in two dogs and a cat. Case 1 was an 11-year-old female Yorkshire terrier with severe bullous keratomalacia in the left eye (OS). A frozen canine amniotic membrane graft and a third eyelid flap were applied. At day 80 postoperatively, only a mild scar and corneal vascularization were present. Case 2 was a 4-year-old female Siamese cat with symblepharon of both eyes after rhinotracheitis. Resection of the conjunctiva and frozen canine amniotic membrane transplant were performed. One month later, there was a little corneal scarring and corneal vascularization. Case 3 was a 6-year-old female terrier with a scleral and corneal mass at the 11-12 o'clock position (OS). Resection of the mass and amniotic membrane transplantation were performed. The mass was a fibrous histiocytoma localized to the sclera and cornea. This eye healed with mild conjunctivalization and no pigmentation. Amniotic membrane transplantation can be used as a method of reconstruction of the ocular surface with good repair of the cornea and minimal scarring in small animals.

[1]  N. Mitsiades,et al.  VEGF-dependent conjunctivalization of the corneal surface. , 2003, Investigative ophthalmology & visual science.

[2]  P. S. M. Barros,et al.  Ceratoplastia lamelar em ces utilizando membrana fetal eqina como enxerto: estudo experimental , 2002 .

[3]  S. Tseng,et al.  Amniotic membrane transplantation for reconstruction after excision of large ocular surface neoplasias , 2002, The British journal of ophthalmology.

[4]  D. Paridaens,et al.  Amniotic membrane transplantation in the management of conjunctival malignant melanoma and primary acquired melanosis with atypia , 2001, The British journal of ophthalmology.

[5]  S. Shimmura,et al.  Antiinflammatory Effects of Amniotic Membrane Transplantation in Ocular Surface Disorders , 2001, Cornea.

[6]  N. Uldbjerg,et al.  Proteoglycans and hyaluronan in human fetal membranes. , 2001, American journal of obstetrics and gynecology.

[7]  M. Meek,et al.  Amnion tube for nerve regeneration. , 2001, Plastic and reconstructive surgery.

[8]  W. Culbertson,et al.  Reduction in corneal haze and apoptosis by amniotic membrane matrix in excimer laser photoablation in rabbits , 2001, Journal of cataract and refractive surgery.

[9]  N. Uldbjerg,et al.  Antibacterial properties of human amnion and chorion in vitro. , 2001, European journal of obstetrics, gynecology, and reproductive biology.

[10]  S. Tseng,et al.  Modulation of acute inflammation and keratocyte death by suturing, blood, and amniotic membrane in PRK. , 2000, Investigative ophthalmology & visual science.

[11]  G. Rao,et al.  Amniotic membrane transplantation in acute chemical and thermal injury. , 2000, American journal of ophthalmology.

[12]  D. H. Ma,et al.  Identification of Antiangiogenic and Antiinflammatory Proteins in Human Amniotic Membrane , 2000, Cornea.

[13]  P. Barros,et al.  Congenital scleral staphyloma in a dog repaired with preserved homologous peritoneum. , 2000, Veterinary ophthalmology.

[14]  S. Tseng,et al.  Amniotic membrane transplantation for symptomatic bullous keratopathy. , 1999, Archives of ophthalmology.

[15]  S. Tseng,et al.  Suppression of transforming growth factor‐beta isoforms, TGF‐β receptor type II, and myofibroblast differentiation in cultured human corneal and limbal fibroblasts by amniotic membrane matrix , 1999 .

[16]  J. D. Alvarenga,et al.  Toracotomia em eqüinos , 1999 .

[17]  A. V. Safatle,et al.  Ceratoplastia lamelar experimental em cães com pericárdio de eqüino conservado , 1999 .

[18]  W. Wee,et al.  Effect of the application of human amniotic membrane on rabbit corneal wound healing after excimer laser photorefractive keratectomy. , 1998, Cornea.

[19]  P. Barros,et al.  The use of xenologous amniotic membrane to repair canine corneal perforation created by penetrating keratectomy. , 1998, Veterinary ophthalmology.

[20]  K. Tsubota,et al.  Transplantation of amniotic membrane and limbal autograft for patients with recurrent pterygium associated with symblepharon , 1998, The British journal of ophthalmology.

[21]  I. Schiebel,et al.  Cytokine and prostaglandin production by amnion cells in response to the addition of different bacteria. , 1998, American journal of obstetrics and gynecology.

[22]  S. Tseng,et al.  Amniotic membrane transplantation for conjunctival surface reconstruction. , 1997, American journal of ophthalmology.

[23]  A. V. Safatle,et al.  Uso do pericárdio de eqüino conservado em glicerina como enxerto penetrante da córnea de cães. Estudo experimental , 1997 .

[24]  S. Tseng,et al.  Comparison of conjunctival autografts, amniotic membrane grafts, and primary closure for pterygium excision. , 1997, Ophthalmology.

[25]  S. Tseng,et al.  Amniotic membrane transplantation for persistent epithelial defects with ulceration. , 1997, American journal of ophthalmology-glaucoma.

[26]  A. V. Safatle,et al.  Implante de peritônio homólogo conservado após ceratectomia lamelar em cães , 1996 .

[27]  K. Tsubota,et al.  Surgical reconstruction of the ocular surface in advanced ocular cicatricial pemphigoid and Stevens-Johnson syndrome. , 1996, American journal of ophthalmology.

[28]  A. V. Safatle,et al.  Reparação cirúrgica da córnea de cão usando pericárdio como prótese , 1995 .

[29]  L. Zardi,et al.  Human amnion epithelial cells assemble tenascins and three fibronectin isoforms in the extracellular matrix , 1993, FEBS letters.

[30]  N. Morris,et al.  Type VII collagen forms an extended network of anchoring fibrils , 1987, The Journal of cell biology.

[31]  T. Allen,et al.  The extracellular matrix of human amniotic epithelium: ultrastructure, composition and deposition. , 1985, Journal of cell science.