Identification of inhibitors of heparin-growth factor interactions from combinatorial libraries of four-component condensation reactions.

[1]  Rebecca C. Wade,et al.  Docking of Glycosaminoglycans to Heparin-Binding Proteins: Validation for aFGF, bFGF, and Antithrombin and Application to IL-8 , 1999 .

[2]  W. Herlihy,et al.  Unique Structures Generated by Ugi 3CC Reactions Using Bifunctional Starting Materials Containing Aldehyde and Carboxylic Acid. , 1999, The Journal of organic chemistry.

[3]  M. Botta,et al.  Synthesis and binding mode of heterocyclic analogues of suramin inhibiting the human basic fibroblast growth factor. , 1998, Bioorganic & medicinal chemistry.

[4]  S. Ben‐Sasson,et al.  Inhibition of Fibroblast Growth Factor-2 Activity by a Synthetic Heparin Mimetic Modulation of Fibroblast Growth Factor-2 Receptor Binding, Dimerization, Signaling, and Angiogenic Activity by a Synthetic Heparin-mimicking Polyanionic Compound Direct Interaction between Rg-13577 and Fgf-2 Was Dem- On , 2022 .

[5]  M. Barinaga Designing Therapies That Target Tumor Blood Vessels , 1997, Science.

[6]  M. Salmivirta,et al.  Heparan sulfate : a piece of information , 2004 .

[7]  D C Rees,et al.  Heparin Structure and Interactions with Basic Fibroblast Growth Factor , 1996, Science.

[8]  K. Alitalo,et al.  Endothelial receptor tyrosine kinases involved in angiogenesis , 1995, The Journal of cell biology.

[9]  G. Waksman,et al.  FGF binding and FGF receptor activation by synthetic heparan-derived di- and trisaccharides. , 1995, Science.

[10]  H. Margalit,et al.  Comparative analysis of structurally defined heparin binding sequences reveals a distinct spatial distribution of basic residues. , 1993, The Journal of biological chemistry.

[11]  T. Maciag,et al.  The heparin-binding (fibroblast) growth factor family of proteins. , 1989, Annual review of biochemistry.

[12]  Ivar Ugi,et al.  The α‐Addition of Immonium Ions and Anions to Isonitriles Accompanied by Secondary Reactions , 1962 .