A novel simulation algorithm for soft tissue compression

This paper presents a novel general approach to simulation of soft tissue compression. A theoretical framework of the compression algorithm has been developed and implemented, based on the concept of a simple spring. The volume subjected to compression is divided into a number of “model elements”, each one consisting of 27 nodes. The nodes are connected with springs. The mechanical properties of the tissues are assumed to be linear and isotropic. The compressed volume remains constant due to the introduced concept of spring variable equilibrium lengths. Initial settings for compression simulation are introduced in order that the algorithm converges faster. The developed compression algorithm was used to model breast compression during a standard mammography examination. Specifically, the method was applied to a high-resolution three-dimensional software breast phantom, composed to have a medium glandularity and calcification abnormalities. The compression was set to 50%. Results showed that the abnormalities maintain their shape and dimensions during the compression, while the surrounding breast tissues undergo considerable deformation and displacement. A “decompression” algorithm was also applied to test the reversibility of the model.

[1]  R. Howe,et al.  Breast Tissue Stiffness in Compression is Correlated to Histological Diagnosis , 1999 .

[2]  K Bliznakova,et al.  Dual-energy mammography: simulation studies. , 2006, Physics in medicine and biology.

[3]  Dimitris N. Metaxas,et al.  Methods for Modeling and Predicting Mechanical Deformations of the Breast Under External Perturbations , 2001, MICCAI.

[4]  Claude Cadoz,et al.  Computational Physics : A Modeler - Simulator for animated physical Objects , 1991, Eurographics.

[5]  K Bliznakova,et al.  A three-dimensional breast software phantom for mammography simulation. , 2003, Physics in medicine and biology.

[6]  Donald McLean,et al.  The application of breast compression in mammography: a new perspective , 2004 .

[7]  J. Z. Zhu,et al.  The finite element method , 1977 .

[8]  Dimitris N. Metaxas,et al.  A deformable finite element model of the breast for predicting mechanical deformations under external perturbations. , 2001, Academic radiology.

[9]  Dimitris N. Metaxas,et al.  A finite element model of the breast for predicting mechanical deformations during biopsy procedures , 2000, Proceedings IEEE Workshop on Mathematical Methods in Biomedical Image Analysis. MMBIA-2000 (Cat. No.PR00737).

[10]  Mathieu Desbrun,et al.  Animating soft substances with implicit surfaces , 1995, SIGGRAPH.

[11]  P. Meseure,et al.  Deformable Body Simulation with adaptive subdivision and cuttings , 1997 .

[12]  R Clavel,et al.  Force feedback for virtual reality based minimally invasive surgery simulator. , 1996, Studies in health technology and informatics.