Automated LC-LC-MS-MS platform using binary ion-exchange and gradient reversed-phase chromatography for improved proteomic analyses.

[1]  G. Kroemer,et al.  Mass spectrometric identification of proteins released from mitochondria undergoing permeability transition , 2000, Cell Death and Differentiation.

[2]  S. Gygi,et al.  Quantitative analysis of complex protein mixtures using isotope-coded affinity tags , 1999, Nature Biotechnology.

[3]  A. F. Neuwald,et al.  Purification and biochemical characterization of interchromatin granule clusters , 1999, The EMBO journal.

[4]  J. Yates,et al.  Direct analysis of protein complexes using mass spectrometry , 1999, Nature Biotechnology.

[5]  S. Patterson,et al.  Optimization of capillary chromatography ion trap‐mass spectrometry for identification of gel‐separated proteins , 1998, Electrophoresis.

[6]  J. Foley,et al.  Effect of Sampling Rate on Resolution in Comprehensive Two-Dimensional Liquid Chromatography , 1998 .

[7]  R. Anderegg,et al.  Two-dimensional SEC/RPLC coupled to mass spectrometry for the analysis of peptides. , 1997, Analytical chemistry.

[8]  G. Opiteck,et al.  Comprehensive on-line RPLC-CZE-MS of peptides , 1997 .

[9]  R. Anderegg,et al.  Comprehensive on-line LC/LC/MS of proteins. , 1997, Analytical chemistry.

[10]  J. Yates,et al.  Direct analysis and identification of proteins in mixtures by LC/MS/MS and database searching at the low-femtomole level. , 1997, Analytical chemistry.

[11]  F. Regnier,et al.  Future potential of targeted component analysis by multidimensional liquid chromatography-mass spectrometry. , 1996, Journal of chromatography. A.

[12]  J. Yates,et al.  An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database , 1994, Journal of the American Society for Mass Spectrometry.

[13]  R. Anderegg,et al.  Two-dimensional microcolumn HPLC coupled to a single-quadrupole mass spectrometer for the elucidation of sequence tags and peptide mapping† , 1998 .

[14]  S. Patterson,et al.  Comparison of in‐gel and on‐membrane digestion methods at low to sub‐pmol level for subsequent peptide and fragment‐ion mass analysis using matrix‐assisted laser‐desorption/ionization mass spectrometry , 1997, Electrophoresis.

[15]  John R. Yates,et al.  A STRATEGY FOR THE IDENTIFICATION OF PROTEINS LOCALIZED TO SUBCELLULAR SPACES : APPLICATION TO E. COLI PERIPLASMIC PROTEINS , 1997 .

[16]  J. Henion,et al.  On-line immunoaffinity extraction-coupled column capillary liquid chromatography/tandem mass spectrometry: trace analysis of LSD analogs and metabolites in human urine. , 1996, Analytical chemistry.