Expression of death-associated protein kinase during tumour progression of human renal cell carcinomas: hypermethylation-independent mechanisms of inactivation.
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C. Suschek | W. Schulz | H. Geddert | C. Mahotka | H. Gabbert | Mohamed Hassan | A. Florl | N. Wethkamp | U. Ramp
[1] P. Malfertheiner,et al. Promoter hypermethylation of p16INK4a, E-cadherin, O6-MGMT, DAPK and FHIT in adenocarcinomas of the esophagus, esophagogastric junction and proximal stomach. , 2005, International journal of oncology.
[2] F. Chan,et al. Promoter hypermethylation of Death-associated protein-kinase gene associated with advance stage gastric cancer. , 2005, Oncology reports.
[3] Jia-Ren Lin,et al. Bidirectional signals transduced by DAPK–ERK interaction promote the apoptotic effect of DAPK , 2005, The EMBO journal.
[4] Li Mao,et al. Hypermethylation of the death-associated protein kinase promoter attenuates the sensitivity to TRAIL-induced apoptosis in human non-small cell lung cancer cells. , 2004, Molecular cancer research : MCR.
[5] Tsuyoshi Saito,et al. Death-associated protein kinase (DAP kinase) alteration in soft tissue leiomyosarcoma: Promoter methylation or homozygous deletion is associated with a loss of DAP kinase expression. , 2004, Human pathology.
[6] U. Lehmann,et al. Low level of DAP-kinase DNA methylation in myelodysplastic syndrome. , 2004, Blood.
[7] A. Kimchi,et al. DAP-kinase-mediated morphological changes are localization dependent and involve myosin-II phosphorylation , 2004, Cell Death and Differentiation.
[8] D. Altieri. Survivin, versatile modulation of cell division and apoptosis in cancer , 2003, Oncogene.
[9] Suzanne Cory,et al. The Bcl-2 family: roles in cell survival and oncogenesis , 2003, Oncogene.
[10] R. Korneluk,et al. The inhibitors of apoptosis: there is more to life than Bcl2 , 2003, Oncogene.
[11] L. Hesson,et al. Multigene methylation analysis of Wilms' tumour and adult renal cell carcinoma , 2003, Oncogene.
[12] S. Lam,et al. Epigenetic down-regulation of death-associated protein kinase in lung cancers. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[13] M. Esteller. CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future , 2002, Oncogene.
[14] C. Suschek,et al. Distinct in vivo expression patterns of survivin splice variants in renal cell carcinomas , 2002, International journal of cancer.
[15] Kenichi Harada,et al. Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines , 2002, Oncogene.
[16] M. Toyota,et al. DNA methylation and histone deacetylation associated with silencing DAP kinase gene expression in colorectal and gastric cancers , 2002, British Journal of Cancer.
[17] A. Kimchi,et al. DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death , 2002, The Journal of cell biology.
[18] W. Farrell,et al. Preferential loss of Death Associated Protein kinase expression in invasive pituitary tumours is associated with either CpG island methylation or homozygous deletion , 2002, Oncogene.
[19] M. Eisenstein,et al. The Pro-apoptotic Function of Death-associated Protein Kinase Is Controlled by a Unique Inhibitory Autophosphorylation-based Mechanism* , 2001, The Journal of Biological Chemistry.
[20] E. Mark,et al. Promoter methylation of DAP-kinase: association with advanced stage in non-small cell lung cancer , 2001, Oncogene.
[21] Y. Tomita,et al. Role of Hypermethylation of DAP-Kinase CpG Island in the Development of Thyroid Lymphoma , 2000, Laboratory Investigation.
[22] P. Wernet,et al. Novel mutations of the von Hippel‐Lindau tumor‐suppressor gene and rare DNA hypermethylation in renal‐cell carcinoma cell lines of the clear‐cell type , 2000, International journal of cancer.
[23] P. Krammer,et al. Deficient activation of CD95 (APO-1/ Fas)-mediated apoptosis: a potential factor of multidrug resistance in human renal cell carcinoma , 2000, British Journal of Cancer.
[24] J. Herman,et al. Gene promoter hypermethylation in tumors and serum of head and neck cancer patients. , 2000, Cancer research.
[25] A. Kimchi,et al. Dap-Kinase Participates in TNF-α–And FAS-Induced Apoptosis and Its Function Requires the Death Domain , 1999, The Journal of cell biology.
[26] J. Herman,et al. Hypermethylation of the DAP-kinase CpG island is a common alteration in B-cell malignancies. , 1999, Blood.
[27] E. Koonin,et al. The domains of death: evolution of the apoptosis machinery. , 1999, Trends in biochemical sciences.
[28] D. Carter. TNM Classification of Malignant Tumors , 1998 .
[29] A. Kimchi. DAP genes: novel apoptotic genes isolated by a functional approach to gene cloning. , 1998, Biochimica et Biophysica Acta.
[30] S. Polak‐Charcon,et al. DAP kinase links the control of apoptosis to metastasis , 1997, Nature.
[31] Peter A. Jones,et al. DAP-kinase loss of expression in various carcinoma and B-cell lymphoma cell lines: possible implications for role as tumor suppressor gene , 1997, Oncogene.
[32] P. Jones,et al. Genetic and epigenetic aspects of DNA methylation on genome expression, evolution, mutation and carcinogenesis. , 1997, Carcinogenesis.
[33] A. Kimchi,et al. DAP‐kinase is a Ca2+/calmodulin‐dependent, cytoskeletal‐associated protein kinase, with cell death‐inducing functions that depend on its catalytic activity , 1997, The EMBO journal.
[34] M. Raff,et al. Programmed Cell Death in Animal Development , 1997, Cell.
[35] R. Moll,et al. Chromophilic renal cell carcinoma: cytomorphological and cytogenetic characterisation of four permanent cell lines. , 1996, British Journal of Cancer.
[36] J. Herman,et al. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[37] S. Störkel,et al. Establishment and characterization of two divergent cell lines derived from a human chromophobe renal cell carcinoma. , 1995, The American journal of pathology.
[38] A. Levine,et al. The p53 tumour suppressor gene , 1991, Nature.
[39] P. Chomczyński,et al. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. , 1987, Analytical biochemistry.
[40] W. Thoenes,et al. Histopathology and classification of renal cell tumors (adenomas, oncocytomas and carcinomas). The basic cytological and histopathological elements and their use for diagnostics. , 1986, Pathology, research and practice.
[41] R. Moll,et al. Cytomorphological, cytogenetic, and molecular biological characterization of four new human renal carcinoma cell lines of the clear cell type , 2004, Virchows Archiv.
[42] Jia-Yun Chen,et al. TGF-β induces apoptosis through Smad-mediated expression of DAP-kinase , 2002, Nature Cell Biology.
[43] Gustavo Droguett,et al. DAP kinase activates a p19ARF/p53-mediated apoptotic checkpoint to suppress oncogenic transformation , 2000, Nature Cell Biology.
[44] J. Herman,et al. Alterations in DNA methylation: a fundamental aspect of neoplasia. , 1998, Advances in cancer research.
[45] C. Rudin,et al. Apoptosis and disease: regulation and clinical relevance of programmed cell death. , 1997, Annual review of medicine.
[46] A. Kimchi,et al. Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death. , 1995, Genes & development.