论文信息 - 2-Amino-3-cyano-4-(4-methoxyphenyl)-1,4,5,6-tetrahydrobenzo[h]chromene

2-Amino-3-cyano-4-(4-methoxyphenyl)-1,4,5,6-tetrahydrobenzo[h]chromene

The title compound, C21H18N2O2, has been synthesized by the reaction of 2-(4-methoxyphenylmethylidene)-3,4-dihydronaphthalen-1(2H)-one and malononitrile in refluxing ethyl alcohol catalyzed by KF–Al2O3. The pyran ring adopts a half-chair conformation, while the fused, partially saturated six-membered ring is in a distorted boat form.

D. Shi | Xiang-Shan Wang | S. Tu | Yuling Li

[1] J. Sanz-Aparicio,et al. 1-Aminocyclohexene-2,4-dicarbonitrile derivatives. Syntheses and structural study , 1995 .

[2] M. H. Elnagdi,et al. Nitriles in heterocyclic synthesis: novel synsthesis of benzo[c]-coumarin and of benzo[c]pyrano[3,2-c]quinoline derivatives , 1987 .

2-Amino-3-cyano-4-(4-methoxy­phenyl)-1,4,5,6-tetra­hydro­benzo­[h]­chromene

2-Amino-3-cyano-4-(4-methoxyphenyl)-1,4,5,6-tetrahydrobenzo[h]chromene