Carbon nanotube‐enhanced thermal destruction of cancer cells in a noninvasive radiofrequency field

Single‐walled carbon nanotubes (SWNTs) have remarkable physicochemical properties that may have several medical applications. The authors have discovered a novel property of SWNTs—heat release in a radiofrequency (RF) field—that they hypothesized may be used to produce thermal cytotoxicity in malignant cells.

[1]  H. Dai,et al.  In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice. , 2020, Nature nanotechnology.

[2]  Steven A Curley,et al.  Mammalian pharmacokinetics of carbon nanotubes using intrinsic near-infrared fluorescence , 2006, Proceedings of the National Academy of Sciences.

[3]  Yuan Zhang,et al.  Delivery of Telomerase Reverse Transcriptase Small Interfering RNA in Complex with Positively Charged Single-Walled Carbon Nanotubes Suppresses Tumor Growth , 2006, Clinical Cancer Research.

[4]  M. Prato,et al.  Functionalized carbon nanotubes are non-cytotoxic and preserve the functionality of primary immune cells. , 2006, Nano letters.

[5]  M. Prato,et al.  Tissue biodistribution and blood clearance rates of intravenously administered carbon nanotube radiotracers. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[6]  Xiaohua Huang,et al.  Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorods. , 2006, Journal of the American Chemical Society.

[7]  Harm H. Kampinga,et al.  Cell biological effects of hyperthermia alone or combined with radiation or drugs: A short introduction to newcomers in the field , 2006, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[8]  L. Ellis,et al.  Early and late complications after radiofrequency ablation of malignant liver tumors in 608 patients , 2004, Annals of Surgical Oncology.

[9]  D. Haemmerich,et al.  Thermal tumour ablation: Devices, clinical applications and future directions , 2005, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[10]  Zhuang Liu,et al.  Functionalization of carbon nanotubes via cleavable disulfide bonds for efficient intracellular delivery of siRNA and potent gene silencing. , 2005, Journal of the American Chemical Society.

[11]  H. Dai,et al.  Carbon nanotubes as multifunctional biological transporters and near-infrared agents for selective cancer cell destruction. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[12]  Jarod C Finlay,et al.  Determination of the distribution of light, optical properties, drug concentration, and tissue oxygenation in-vivo in human prostate during motexafin lutetium-mediated photodynamic therapy. , 2005, Journal of photochemistry and photobiology. B, Biology.

[13]  Werner A. Kaiser,et al.  Towards breast cancer treatment by magnetic heating , 2005 .

[14]  Werner A. Kaiser,et al.  Maghemite nanoparticles with very high AC-losses for application in RF-magnetic hyperthermia , 2004 .

[15]  M. Fuhrer,et al.  Extraordinary Mobility in Semiconducting Carbon Nanotubes , 2004 .

[16]  I. Kinloch,et al.  Ultra-low electrical percolation threshold in carbon-nanotube-epoxy composites , 2003 .

[17]  Paolo Bernardi,et al.  Specific absorption rate and temperature elevation in a subject exposed in the far-field of radio-frequency sources operating in the 10-900-MHz range , 2003, IEEE Transactions on Biomedical Engineering.

[18]  Douglas B. Evans,et al.  Neoplasms of the Exocrine Pancreas , 2003 .

[19]  R. Smalley,et al.  Structure-Assigned Optical Spectra of Single-Walled Carbon Nanotubes , 2002, Science.

[20]  W. D. de Heer,et al.  Carbon Nanotubes--the Route Toward Applications , 2002, Science.

[21]  Gilbert C Walker,et al.  Noncovalent engineering of carbon nanotube surfaces by rigid, functional conjugated polymers. , 2002, Journal of the American Chemical Society.

[22]  P. McEuen,et al.  Single-walled carbon nanotube electronics , 2002 .

[23]  E. Anderson,et al.  Scanned probe microscopy of electronic transport in carbon nanotubes. , 2000, Physical review letters.

[24]  S. Variend.  Primary neoplasms of the liver , 1993 .

[25]  S. Iijima.  Helical microtubules of graphitic carbon , 1991, Nature.