The Effects of MicroRNAs in the Development of Heart Failure

[1]  G. Santulli,et al.  Functional Role of microRNAs in Regulating Cardiomyocyte Death , 2022, Cells.

[2]  P. Kennel,et al.  A Review on the Evolving Roles of MiRNA-Based Technologies in Diagnosing and Treating Heart Failure , 2021, Cells.

[3]  Hao Li,et al.  Circulating miR‐19b‐3p as a Novel Prognostic Biomarker for Acute Heart Failure , 2021, Journal of the American Heart Association.

[4]  S. Mi,et al.  Downregulation of miR-128 Ameliorates Ang II-Induced Cardiac Remodeling via SIRT1/PIK3R1 Multiple Targets , 2021, Oxidative medicine and cellular longevity.

[5]  N. Younis,et al.  Pachymic Acid Attenuated Doxorubicin-Induced Heart Failure by Suppressing miR-24 and Preserving Cardiac Junctophilin-2 in Rats , 2021, International journal of molecular sciences.

[6]  Jie Hao,et al.  miR-320 accelerates chronic heart failure with cardiac fibrosis through activation of the IL6/STAT3 axis , 2021, Aging.

[7]  Yan Wang,et al.  LncRNA CAIF suppresses LPS‐induced inflammation and apoptosis of cardiomyocytes through regulating miR‐16 demethylation , 2021, Immunity, inflammation and disease.

[8]  Peiqing Liu,et al.  MicroRNA-34c-5p provokes isoprenaline-induced cardiac hypertrophy by modulating autophagy via targeting ATG4B , 2021, Acta pharmaceutica Sinica. B.

[9]  Li Zhao,et al.  MiR-590-5p inhibits pathological hypertrophy mediated heart failure by targeting RTN4 , 2021, Journal of Molecular Histology.

[10]  Xingde Liu,et al.  MiR-125b inhibits cardiomyocyte apoptosis by targeting BAK1 in heart failure , 2021, Molecular Medicine.

[11]  Gan Luo,et al.  miR-320a in serum exosomes promotes myocardial fibroblast proliferation via regulating the PIK3CA/Akt/mTOR signaling pathway in HEH2 cells , 2021, Experimental and therapeutic medicine.

[12]  Zhongjie Sun,et al.  MicroRNA 379 Regulates Klotho Deficiency–Induced Cardiomyocyte Apoptosis Via Repression of Smurf1 , 2021, Hypertension.

[13]  Jia-yu Shi,et al.  MicroRNA-17-5p Promotes Cardiac Hypertrophy by Targeting Mfn2 to Inhibit Autophagy , 2021, Cardiovascular Toxicology.

[14]  Xinyu Bai,et al.  microRNA‐454‐mediated NEDD4‐2/TrkA/cAMP axis in heart failure: Mechanisms and cardioprotective implications , 2021, Journal of cellular and molecular medicine.

[15]  Q. Yin,et al.  Cardiac‐specific overexpression of miR‐122 induces mitochondria‐dependent cardiomyocyte apoptosis and promotes heart failure by inhibiting Hand2 , 2021, Journal of cellular and molecular medicine.

[16]  W. Koch,et al.  In Vivo Stimulation of α- and β-Adrenoceptors in Mice Differentially Alters Small RNA Content of Circulating Extracellular Vesicles , 2021, Cells.

[17]  Zheng Wen,et al.  The double face of miR-320: cardiomyocytes-derived miR-320 deteriorated while fibroblasts-derived miR-320 protected against heart failure induced by transverse aortic constriction , 2021, Signal Transduction and Targeted Therapy.

[18]  D. Pascual-Figal,et al.  The miRNA199a/SIRT1/P300/Yy1/sST2 signaling axis regulates adverse cardiac remodeling following MI , 2021, Scientific Reports.

[19]  Shuai Sun,et al.  MicroRNA-138-5p drives the progression of heart failure via inhibiting sirtuin 1 signaling , 2021, Molecular medicine reports.

[20]  T. Meitinger,et al.  MicroRNA-21–Dependent Macrophage-to-Fibroblast Signaling Determines the Cardiac Response to Pressure Overload , 2021, Circulation.

[21]  K. Wu,et al.  MicroRNA-520d-3p alleviates hypoxia/reoxygenation-induced damage in human cardiomyocytes by targeting ATG-12 , 2021, Journal of Thrombosis and Thrombolysis.

[22]  Xin Yang,et al.  Knockdown of lncRNA TTTY15 alleviates myocardial ischemia–reperfusion injury through the miR‐374a‐5p/FOXO1 axis , 2020, IUBMB life.

[23]  Yan He,et al.  Silenced SOX2‐OT alleviates ventricular arrhythmia associated with heart failure by inhibiting NLRP3 expression via regulating miR‐2355‐3p , 2020, Immunity, inflammation and disease.

[24]  W. Lau,et al.  mir15a/mir16‐1 cluster and its novel targeting molecules negatively regulate cardiac hypertrophy , 2020, Clinical and translational medicine.

[25]  Jing Xu,et al.  Sirt1 improves heart failure through modulating the NF-κB p65/microRNA-155/BNDF signaling cascade , 2020, Aging.

[26]  Da-Zhi Wang,et al.  Adeno-associated virus-mediated delivery of anti-miR-199a tough decoys attenuates cardiac hypertrophy by targeting PGC-1alpha , 2020, Molecular therapy. Nucleic acids.

[27]  S. Solomon,et al.  Novel antisense therapy targeting microRNA-132 in patients with heart failure: results of a first-in-human Phase 1b randomized, double-blind, placebo-controlled study , 2020, European heart journal.

[28]  E. Gao,et al.  MicroRNA-21 Mediates a Positive Feedback on Angiotensin II-Induced Myofibroblast Transformation , 2020, Journal of inflammation research.

[29]  Alexander R. Pico,et al.  Mir-30d Regulates Cardiac Remodeling by Intracellular And Paracrine Signaling. , 2020, Circulation research.

[30]  A. Richards,et al.  microRNA-221 Inhibits Latent TGF-β1 Activation through Targeting Thrombospondin-1 to Attenuate Kidney Failure-Induced Cardiac Fibrosis , 2020, Molecular therapy. Nucleic acids.

[31]  Godfrey L. Smith,et al.  Exercise training reveals micro-RNAs associated with improved cardiac function and electrophysiology in rats with heart failure after myocardial infarction. , 2020, Journal of molecular and cellular cardiology.

[32]  H. Xia,et al.  Over-expression of microRNA-145 drives alterations in β-adrenergic signaling and attenuates cardiac remodeling in heart failure post myocardial infarction , 2020, Aging.

[33]  Yadong Long,et al.  SP1‐induced SNHG14 aggravates hypertrophic response in in vitro model of cardiac hypertrophy via up‐regulation of PCDH17 , 2020, Journal of cellular and molecular medicine.

[34]  C. Tian,et al.  Extracellular vesicular MicroRNA-27a* contributes to cardiac hypertrophy in chronic heart failure. , 2020, Journal of molecular and cellular cardiology.

[35]  Yunshan Cao,et al.  ETS2 and microRNA-155 regulate the pathogenesis of heart failure through targeting and regulating GPR18 expression , 2020, Experimental and therapeutic medicine.

[36]  Huiqin Chen,et al.  DSCAM-AS1 mediates pro-hypertrophy role of GRK2 in cardiac hypertrophy aggravation via absorbing miR-188-5p , 2020, In Vitro Cellular & Developmental Biology - Animal.

[37]  M. Zong,et al.  Differentially expressed lnc‐NOS2P3‐miR‐939‐5p axis in chronic heart failure inhibits myocardial and endothelial cells apoptosis via iNOS/TNFα pathway , 2020, Journal of cellular and molecular medicine.

[38]  Yuan Zhang,et al.  Combined detection of miR-21-5p, miR-30a-3p, miR-30a-5p, miR-155-5p, miR-216a and miR-217 for screening of early heart failure diseases , 2020, Bioscience reports.

[39]  Wei Zhang,et al.  LncRNA KCNQ1OT1 attenuates sepsis-induced myocardial injury via regulating miR-192-5p/XIAP axis , 2020, Experimental biology and medicine.

[40]  M. Ponnusamy,et al.  NFATc3-dependent expression of miR-153-3p promotes mitochondrial fragmentation in cardiac hypertrophy by impairing mitofusin-1 expression , 2020, Theranostics.

[41]  J. Piao,et al.  MicroRNA302-367-PI3K-PTEN-AKT-mTORC1 pathway promotes the development of cardiac hypertrophy through controlling autophagy , 2019, In Vitro Cellular & Developmental Biology - Animal.

[42]  S. Zhang,et al.  Long Noncoding RNA FTX Reduces Hypertrophy of Neonatal Mouse Cardiac Myocytes and Regulates the PTEN/PI3K/Akt Signaling Pathway by Sponging MicroRNA-22 , 2019, Medical science monitor : international medical journal of experimental and clinical research.

[43]  Yonggang Cao,et al.  MSTN Attenuates Cardiac Hypertrophy through Inhibition of Excessive Cardiac Autophagy by Blocking AMPK /mTOR and miR-128/PPARγ/NF-κB , 2019, Molecular therapy. Nucleic acids.

[44]  Cong Li,et al.  MiR-338-5p ameliorates pathological cardiac hypertrophy by targeting CAMKIIδ , 2019, Archives of Pharmacal Research.

[45]  O. Liew,et al.  Heart Failure with Reduced Ejection Fraction (HFrEF) and Preserved Ejection Fraction (HFpEF): The Diagnostic Value of Circulating MicroRNAs , 2019, Cells.

[46]  A. Eid,et al.  MicroRNAs in Cardiac Hypertrophy , 2019, International journal of molecular sciences.

[47]  Chaoqian Xu,et al.  Long non‐coding RNA cardiac hypertrophy‐associated regulator governs cardiac hypertrophy via regulating miR‐20b and the downstream PTEN/AKT pathway , 2019, Journal of cellular and molecular medicine.

[48]  Junping Zhang,et al.  The microRNA in ventricular remodeling: the miR-30 family , 2019, Bioscience reports.

[49]  K. Yan,et al.  Mitochondrial miR-762 regulates apoptosis and myocardial infarction by impairing ND2 , 2019, Cell Death & Disease.

[50]  A. Richards,et al.  MicroRNA-221 Is Cardioprotective and Anti-fibrotic in a Rat Model of Myocardial Infarction , 2019, Molecular therapy. Nucleic acids.

[51]  C. Shao,et al.  RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure , 2019, Proceedings of the National Academy of Sciences.

[52]  N. Frangogiannis.  Cardiac fibrosis: Cell biological mechanisms, molecular pathways and therapeutic opportunities. , 2019, Molecular aspects of medicine.

[53]  M. Halushka,et al.  Opportunities for microRNAs in the Crowded Field of Cardiovascular Biomarkers. , 2019, Annual review of pathology.

[54]  Joungmok Kim,et al.  Autophagy: An Essential Degradation Program for Cellular Homeostasis and Life , 2018, Cells.

[55]  S. Blankenberg,et al.  Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives. , 2018, European heart journal.

[56]  Yan Zhang,et al.  Programmed necrosis in cardiomyocytes: mitochondria, death receptors and beyond , 2018, British journal of pharmacology.

[57]  Jichun Liu,et al.  miR‐21 promotes cardiac fibroblast‐to‐myofibroblast transformation and myocardial fibrosis by targeting Jagged1 , 2018, Journal of cellular and molecular medicine.

[58]  C. Tian,et al.  Myocardial infarction-induced microRNA-enriched exosomes contribute to cardiac Nrf2 dysregulation in chronic heart failure. , 2018, American journal of physiology. Heart and circulatory physiology.

[59]  Songwen Chen,et al.  MicroRNA‐30c suppresses the pro‐fibrogenic effects of cardiac fibroblasts induced by TGF‐β1 and prevents atrial fibrosis by targeting TGFβRII , 2018, Journal of cellular and molecular medicine.

[60]  M. Goumans,et al.  MicroRNA-221/222 Family Counteracts Myocardial Fibrosis in Pressure Overload–Induced Heart Failure , 2018, Hypertension.

[61]  Saumya Das,et al.  Extracellular Vesicles in Cardiovascular Theranostics , 2017, Theranostics.

[62]  Y. Li,et al.  Knockdown of MicroRNA-122 Protects H9c2 Cardiomyocytes from Hypoxia-Induced Apoptosis and Promotes Autophagy , 2017, Medical science monitor : international medical journal of experimental and clinical research.

[63]  Xuejun Jiang,et al.  Renal sympathetic denervation alleviates myocardial fibrosis following isoproterenol-induced heart failure , 2017, Molecular medicine reports.

[64]  D-W Ge,et al.  Mir-21 Promotes Cardiac Fibrosis After Myocardial Infarction Via Targeting Smad7 , 2017, Cellular Physiology and Biochemistry.

[65]  A. Ballabio,et al.  Molecular definitions of autophagy and related processes , 2017, The EMBO journal.

[66]  P. Shi,et al.  miR-21 enhances cardiac fibrotic remodeling and fibroblast proliferation via CADM1/STAT3 pathway , 2017, BMC Cardiovascular Disorders.

[67]  Yanjie Lu,et al.  Let-7a regulates expression of β1-adrenoceptors and forms a negative feedback circuit with the β1-adrenoceptor signaling pathway in chronic ischemic heart failure , 2017, Oncotarget.

[68]  Gaetano Santulli,et al.  Adrenergic signaling in heart failure and cardiovascular aging. , 2016, Maturitas.

[69]  Y. Pinto,et al.  MicroRNAs in heart failure: from biomarker to target for therapy , 2016, European journal of heart failure.

[70]  P. Ponikowski,et al.  Signature of circulating microRNAs in patients with acute heart failure , 2016, European journal of heart failure.

[71]  E. Creemers,et al.  Function and Therapeutic Potential of Noncoding RNAs in Cardiac Fibrosis. , 2016, Circulation research.

[72]  S. Paiva,et al.  Cardiac Remodeling: Concepts, Clinical Impact, Pathophysiological Mechanisms and Pharmacologic Treatment , 2016, Arquivos brasileiros de cardiologia.

[73]  Jianqin Jiao,et al.  MicroRNA-103/107 Regulate Programmed Necrosis and Myocardial Ischemia/Reperfusion Injury Through Targeting FADD. , 2015, Circulation research.

[74]  T. Lüscher.  Heart failure: the cardiovascular epidemic of the 21st century. , 2015, European heart journal.

[75]  Piotr Ponikowski,et al.  Heart failure: preventing disease and death worldwide , 2014, ESC heart failure.

[76]  S. Kauppinen,et al.  Silencing of miR-34a Attenuates Cardiac Dysfunction in a Setting of Moderate, but Not Severe, Hypertrophic Cardiomyopathy , 2014, PloS one.

[77]  Y. Cheng,et al.  Let-7 in Cardiovascular Diseases, Heart Development and Cardiovascular Differentiation from Stem Cells , 2013, International journal of molecular sciences.

[78]  A. Criollo,et al.  Cardiomyocyte death: mechanisms and translational implications , 2011, Cell Death and Disease.

[79]  J. McMullen,et al.  Molecular distinction between physiological and pathological cardiac hypertrophy: experimental findings and therapeutic strategies. , 2010, Pharmacology & therapeutics.

[80]  D. Bartel.  MicroRNAs: Target Recognition and Regulatory Functions , 2009, Cell.

[81]  R. Shivdasani.  MicroRNAs: regulators of gene expression and cell differentiation. , 2006, Blood.

[82]  Douglas L Mann,et al.  Mechanisms and models in heart failure: the biomechanical model and beyond. , 2005, Circulation.

[83]  D. Bartel.  MicroRNAs Genomics, Biogenesis, Mechanism, and Function , 2004, Cell.

[84]  F. Verdonck,et al.  Altered Na/Ca exchange activity in cardiac hypertrophy and heart failure: a new target for therapy? , 2002, Cardiovascular research.

[85]  J. Cohn,et al.  Cardiac remodeling--concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf of an International Forum on Cardiac Remodeling. , 2000, Journal of the American College of Cardiology.

[86]  Xue-mei He,et al.  Exosomes released from mesenchymal stem cells overexpressing microRNA-30e ameliorate heart failure in rats with myocardial infarction. , 2021, American journal of translational research.

[87]  W. Kolch,et al.  The long noncoding RNA NRF regulates programmed necrosis and myocardial injury during ischemia and reperfusion by targeting miR-873 , 2016, Cell Death and Differentiation.

[88]  Ayan R Patel,et al.  Left ventricular remodeling in heart failure: current concepts in clinical significance and assessment. , 2011, JACC. Cardiovascular imaging.

[89]  S. Barik,et al.  MicroRNAs: Processing, Maturation, Target Recognition and Regulatory Functions. , 2011, Molecular and cellular pharmacology.