miRNAs as cornerstones in adipogenesis and obesity.

[1]  Sylvia F. Fawzi,et al.  The role of miRNAs in insulin resistance and diabetic macrovascular complications - A review. , 2023, International journal of biological macromolecules.

[2]  J. Rood,et al.  Circulating thrifty microRNA is related to insulin sensitivity, adiposity, and energy metabolism in adults with overweight and obesity: the POUNDS Lost trial. , 2022, The American journal of clinical nutrition.

[3]  H. M. El-Husseiny,et al.  miRNAs insights into rheumatoid arthritis: Favorable and detrimental aspects of key performers. , 2022, Life sciences.

[4]  M. Eldeib,et al.  miRNAs as cornerstones in diabetic microvascular complications. , 2022, Molecular genetics and metabolism.

[5]  Ahmed S. Doghish,et al.  The role of miRNAs in ovarian cancer pathogenesis and therapeutic resistance - A focus on signaling pathways interplay. , 2022, Pathology, research and practice.

[6]  M. Sobhy,et al.  Hydroxycitric acid reverses tamoxifen resistance through inhibition of ATP citrate lyase. , 2022, Pathology, research and practice.

[7]  Ahmed S. Doghish,et al.  Beneficial and detrimental aspects of miRNAs as chief players in breast cancer: A comprehensive review. , 2022, International journal of biological macromolecules.

[8]  S. Salem,et al.  Nanocomposite based on gold nanoparticles and carboxymethyl cellulose: Synthesis, characterization, antimicrobial, and anticancer activities , 2022, Journal of Drug Delivery Science and Technology.

[9]  J. Friedman,et al.  miR-130b/301b is a Negative Regulator of Beige Adipogenesis and Energy Metabolism in vitro and in vivo. , 2022, Diabetes.

[10]  Ahmed S. Doghish,et al.  A study of miRNAs as cornerstone in lung cancer pathogenesis and therapeutic resistance: A focus on signaling pathways interplay. , 2022, Pathology, research and practice.

[11]  A. A. Ahmed,et al.  miRNAs as cornerstones in colorectal cancer pathogenesis and resistance to therapy: A spotlight on signaling pathways interplay - A review. , 2022, International journal of biological macromolecules.

[12]  K. Choo,et al.  The MicroRNA-signaling-peroxisome proliferator-activated receptor gamma connection in the modulation of adipogenesis: bioinformatics projection on chicken , 2022, Poultry science.

[13]  M. Zarkesh,et al.  Association of miR-34a and miR-143 levels with PPARγ gene expression in adipose tissues of non-diabetic adults , 2022, Journal of Physiological Anthropology.

[14]  Al-aliaa M. Sallam,et al.  miRNAs inspirations in hepatocellular carcinoma: Detrimental and favorable aspects of key performers. , 2022, Pathology, research and practice.

[15]  C. Sones,et al.  MicroRNAs—A Promising Tool for Asthma Diagnosis and Severity Assessment: A Systematic Review , 2022, Journal of personalized medicine.

[16]  N. Mitro,et al.  Regulatory mechanisms of the early phase of white adipocyte differentiation: an overview , 2022, Cellular and Molecular Life Sciences.

[17]  K. Ross,et al.  Liquid biopsy: Exosomal microRNAs as novel diagnostic and prognostic biomarkers in cancer , 2022, Molecular Cancer.

[18]  Y. Kang,et al.  Identification of MicroRNAs as Potential Blood-Based Biomarkers for Diagnosis and Therapeutic Monitoring of Active Tuberculosis , 2022, Diagnostics.

[19]  A. Ismail,et al.  A review of the biological role of miRNAs in prostate cancer suppression and progression. , 2021, International journal of biological macromolecules.

[20]  A. Kuryłowicz.  microRNAs in Human Adipose Tissue Physiology and Dysfunction , 2021, Cells.

[21]  Y. Zhai,et al.  Gender differences in metabolic rates and thermal comfort in sedentary young males and females at various temperatures , 2021 .

[22]  Eman Mostafa,et al.  Correlation of circulating miRNA-33a and miRNA-122 with lipid metabolism among Egyptian patients with metabolic syndrome , 2021, Journal of Genetic Engineering and Biotechnology.

[23]  Y. Liang,et al.  BMP-2 alleviates heart failure with type 2 diabetes mellitus and doxorubicin-induced AC16 cell injury by inhibiting NLRP3 inflammasome-mediated pyroptosis. , 2021, Experimental and therapeutic medicine.

[24]  R. Price,et al.  Adipocyte, Immune Cells, and miRNA Crosstalk: A Novel Regulator of Metabolic Dysfunction and Obesity , 2021, Cells.

[25]  S. Panda,et al.  Neutralization of variant under investigation B.1.617 with sera of BBV152 vaccinees , 2021, bioRxiv.

[26]  J. Postlethwait,et al.  Evolution after Whole-Genome Duplication: Teleost MicroRNAs , 2021, Molecular biology and evolution.

[27]  R. Carthew,et al.  MicroRNA-mediated regulation of glucose and lipid metabolism , 2021, Nature Reviews Molecular Cell Biology.

[28]  K. Moore,et al.  MicroRNA-33 Inhibits Adaptive Thermogenesis and Adipose Tissue Beiging , 2021, Arteriosclerosis, thrombosis, and vascular biology.

[29]  M. Elshafey,et al.  MicroRNA-567 inhibits cell proliferation and induces cell apoptosis in A549 NSCLC cells by regulating cyclin-dependent kinase 8 , 2021, Saudi journal of biological sciences.

[30]  A. Amin,et al.  Circulating miR-148a-5p and miR-21-5p as Novel Diagnostic Biomarkers in Adult Egyptian Male Patients With Metabolic Syndrome. , 2021, Canadian journal of diabetes.

[31]  E. M. Gedawy,et al.  Design, synthesis, anticancer evaluation, and molecular modelling studies of novel tolmetin derivatives as potential VEGFR-2 inhibitors and apoptosis inducers , 2021, Journal of enzyme inhibition and medicinal chemistry.

[32]  H. Randeva,et al.  Regulatory microRNAs in Brown, Brite and White Adipose Tissue , 2020, Cells.

[33]  J. Martínez,et al.  Intestinal Lipid Metabolism Genes Regulated by miRNAs , 2020, Frontiers in Genetics.

[34]  Wei Liu,et al.  MicroRNA 182 is a Novel Negative Regulator of Adipogenesis by Targeting CCAAT/Enhancer‐Binding Protein α , 2020, Obesity.

[35]  B. Elsadek,et al.  Hydroxycitric acid potentiates the cytotoxic effect of tamoxifen in MCF-7 breast cancer cells through inhibition of ATP citrate lyase , 2020, Steroids.

[36]  I. Fong,et al.  Molecular Mechanisms of Adipogenesis: The Anti-adipogenic Role of AMP-Activated Protein Kinase , 2020, Frontiers in Molecular Biosciences.

[37]  Kou-Juey Wu.  The role of miRNA biogenesis and DDX17 in tumorigenesis and cancer stemness , 2020, Biomedical journal.

[38]  K. Eckel-Mahan,et al.  Adipose Stromal Cell Expansion and Exhaustion: Mechanisms and Consequences , 2020, Cells.

[39]  L. Zan,et al.  MiR-145 reduces the activity of PI3K/Akt and MAPK signaling pathways and inhibits adipogenesis in bovine preadipocytes. , 2020, Genomics.

[40]  Xirong Guo,et al.  The clinical potential of circulating microRNAs in obesity , 2019, Nature Reviews Endocrinology.

[41]  R. Hammer,et al.  miR-26 suppresses adipocyte progenitor differentiation and fat production by targeting Fbxl19 , 2019, Genes & development.

[42]  E. J. Lee,et al.  MicroRNA-27 inhibits adipogenic differentiation in orbital fibroblasts from patients with Graves’ orbitopathy , 2019, PloS one.

[43]  F. Cirillo,et al.  Obesity, Insulin Resistance, and Colorectal Cancer: Could miRNA Dysregulation Play a Role? , 2019, International journal of molecular sciences.

[44]  M. A. Lasunción,et al.  Postprandial Circulating miRNAs in Response to a Dietary Fat Challenge , 2019, Nutrients.

[45]  Brooks Taylor,et al.  Molecular competition in G1 controls when cells simultaneously commit to terminally differentiate and exit the cell-cycle , 2019 .

[46]  O. Mansour,et al.  Potential role of circulating microRNAs (486-5p, 497, 509-5p and 605) in metabolic syndrome Egyptian male patients , 2019, Diabetes, metabolic syndrome and obesity : targets and therapy.

[47]  G. Biagini,et al.  miRNA-218 Targets Lipin-1 and Glucose Transporter Type 4 Genes in 3T3-L1 Cells Treated With Lopinavir/Ritonavir , 2019, Front. Pharmacol..

[48]  L. Kappeler,et al.  Role of miRNA in the Transmission of Metabolic Diseases Associated With Paternal Diet-Induced Obesity , 2019, Front. Genet..

[49]  P. Kuo,et al.  The Roles of MicroRNA in Lung Cancer , 2019, International journal of molecular sciences.

[50]  F. Zheng,et al.  Circulating miR‐143‐3p inhibition protects against insulin resistance in Metabolic Syndrome via targeting of the insulin‐like growth factor 2 receptor , 2019, Translational research : the journal of laboratory and clinical medicine.

[51]  M. Blüher.  Obesity: global epidemiology and pathogenesis , 2019, Nature Reviews Endocrinology.

[52]  A. Fawzy,et al.  Diagnostic Significance of miR-639 and miR-10b in Βreast Cancer Patients , 2019, Meta Gene.

[53]  A. Xu,et al.  Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation , 2019, The Journal of clinical investigation.

[54]  F. Milagro,et al.  MicroRNAs and other non-coding RNAs in adipose tissue and obesity: emerging roles as biomarkers and therapeutic targets. , 2019, Clinical science.

[55]  S. Young,et al.  Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis , 2018, The Journal of clinical investigation.

[56]  K. Saliminejad,et al.  An overview of microRNAs: Biology, functions, therapeutics, and analysis methods , 2018, Journal of cellular physiology.

[57]  J. Cáceres,et al.  Post-transcriptional control of miRNA biogenesis , 2018, RNA.

[58]  A. Baranova,et al.  Adipose may actively delay progression of NAFLD by releasing tumor‐suppressing, anti‐fibrotic miR‐122 into circulation , 2018, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[59]  H. Zhao,et al.  MicroRNA-9-5p promotes osteoporosis development through inhibiting osteogenesis and promoting adipogenesis via targeting Wnt3a. , 2019, European review for medical and pharmacological sciences.

[60]  Atef A Bassyouni,et al.  Plasma endoglin in Type2 diabetic patients with nephropathy. , 2019, Diabetes & metabolic syndrome.

[61]  S. Kalko,et al.  Obesity-associated exosomal miRNAs modulate glucose and lipid metabolism in mice , 2018, Proceedings of the National Academy of Sciences.

[62]  Zhigang Guo,et al.  Obesity-induced overexpression of miRNA-24 regulates cholesterol uptake and lipid metabolism by targeting SR-B1. , 2018, Gene.

[63]  M. Costache,et al.  Adipose tissue engineering and adipogenesis – a review , 2018, Reviews in Biological and Biomedical Sciences.

[64]  Meiling Yan,et al.  MiRNA-92a protects pancreatic B-cell function by targeting KLF2 in diabetes mellitus. , 2018, Biochemical and biophysical research communications.

[65]  M. Morán-Moguel,et al.  Rheumatoid Arthritis and miRNAs: A Critical Review through a Functional View , 2018, Journal of immunology research.

[66]  D. Murugan,et al.  Differential effects of dietary flavonoids on adipogenesis , 2018, European Journal of Nutrition.

[67]  W. Kratzer,et al.  Circulating levels of miR‐122 and nonalcoholic fatty liver disease in pre‐pubertal obese children , 2018, Pediatric obesity.

[68]  R. de Cabo,et al.  Genetic Ablation of miR-33 Increases Food Intake, Enhances Adipose Tissue Expansion, and Promotes Obesity and Insulin Resistance , 2018, Cell reports.

[69]  H. El Amri,et al.  The clinical potential of adipogenesis and obesity-related microRNAs. , 2017, Nutrition, metabolism, and cardiovascular diseases : NMCD.

[70]  J. Yanovski.  Obesity: Trends in underweight and obesity — scale of the problem , 2018, Nature Reviews Endocrinology.

[71]  M. Puzianowska-Kuźnicka,et al.  NGS Reveals Molecular Pathways Affected by Obesity and Weight Loss-Related Changes in miRNA Levels in Adipose Tissue , 2017, International journal of molecular sciences.

[72]  T. Catela Ivković,et al.  microRNAs as cancer therapeutics: A step closer to clinical application. , 2017, Cancer letters.

[73]  Jong Bae Seo,et al.  Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity , 2017, Cell.

[74]  L. Bouchard,et al.  microRNAs in lipoprotein and lipid metabolism: from biological function to clinical application , 2017, Clinical chemistry and laboratory medicine.

[75]  Wei He,et al.  Cytosolic co-delivery of miRNA-34a and docetaxel with core-shell nanocarriers via caveolae-mediated pathway for the treatment of metastatic breast cancer , 2017, Scientific Reports.

[76]  M. Heikenwalder,et al.  miRNA-132 induces hepatic steatosis and hyperlipidaemia by synergistic multitarget suppression , 2017, Gut.

[77]  M. Portillo,et al.  Are miRNA-103, miRNA-107 and miRNA-122 Involved in the Prevention of Liver Steatosis Induced by Resveratrol? , 2017, Nutrients.

[78]  C. Pichon,et al.  Pharmacomodulation of microRNA Expression in Neurocognitive Diseases: Obstacles and Future Opportunities , 2017, Current neuropharmacology.

[79]  Anchal Vishnoi,et al.  MiRNA Biogenesis and Regulation of Diseases: An Overview. , 2017, Methods in molecular biology.

[80]  J. Dou,et al.  MiRNA-34a overexpression inhibits multiple myeloma cancer stem cell growth in mice by suppressing TGIF2. , 2016, American journal of translational research.

[81]  M. Scheideler,et al.  Let-7i-5p represses brite adipocyte function in mice and humans , 2016, Scientific Reports.

[82]  Xing He,et al.  Transplantation of miRNA‐34a overexpressing adipose‐derived stem cell enhances rat nerve regeneration , 2016, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

[83]  W. D. van Marken Lichtenbelt,et al.  Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity , 2016, Nature Communications.

[84]  Praveen Sethupathy,et al.  The Promise and Challenge of Therapeutic MicroRNA Silencing in Diabetes and Metabolic Diseases , 2016, Current Diabetes Reports.

[85]  F. Milagro,et al.  Involvement of miR-539-5p in the inhibition of de novo lipogenesis induced by resveratrol in white adipose tissue. , 2016, Food & function.

[86]  K. Suhre,et al.  Metabolic switch during adipogenesis: From branched chain amino acid catabolism to lipid synthesis. , 2016, Archives of biochemistry and biophysics.

[87]  A. Seyhan,et al.  Altered levels of circulating cytokines and microRNAs in lean and obese individuals with prediabetes and type 2 diabetes. , 2016, Molecular bioSystems.

[88]  S. Muljo,et al.  Prospects for Therapeutic Targeting of MicroRNAs in Human Immunological Diseases , 2015, The Journal of Immunology.

[89]  S. Ray,et al.  Hepatocellular carcinoma and microRNA: new perspectives on therapeutics and diagnostics. , 2015, Advanced drug delivery reviews.

[90]  T. Roberts.  The microRNA Machinery. , 2015, Advances in experimental medicine and biology.

[91]  J. Kemper,et al.  MicroRNA 34a Inhibits Beige and Brown Fat Formation in Obesity in Part by Suppressing Adipocyte Fibroblast Growth Factor 21 Signaling and SIRT1 Function , 2014, Molecular and Cellular Biology.

[92]  Jian Peng,et al.  MicroRNAs: emerging roles in adipogenesis and obesity. , 2014, Cellular signalling.

[93]  M. Trajkovski,et al.  MiR-27 orchestrates the transcriptional regulation of brown adipogenesis. , 2014, Metabolism: clinical and experimental.

[94]  R. Knight,et al.  miR-34: from bench to bedside , 2014, Oncotarget.

[95]  S. Mandrup,et al.  Peroxisome Proliferator-Activated Receptor γ and C/EBPα Synergistically Activate Key Metabolic Adipocyte Genes by Assisted Loading , 2013, Molecular and Cellular Biology.

[96]  C. Jung,et al.  MicroRNA-146b promotes adipogenesis by suppressing the SIRT1-FOXO1 cascade , 2013, EMBO molecular medicine.

[97]  Jian Peng,et al.  MiR-224 impairs adipocyte early differentiation and regulates fatty acid metabolism. , 2013, The international journal of biochemistry & cell biology.

[98]  Huangxian Ju,et al.  MicroRNA: function, detection, and bioanalysis. , 2013, Chemical reviews.

[99]  S. Kauppinen,et al.  Treatment of HCV infection by targeting microRNA. , 2013, The New England journal of medicine.

[100]  Peng Cheng,et al.  The role of microRNAs in adipocyte differentiation , 2013, Frontiers of Medicine.

[101]  O. MacDougald,et al.  Adipose tissue stem cells meet preadipocyte commitment: going back to the future[S] , 2012, Journal of Lipid Research.

[102]  R. DePinho,et al.  Hepatic suppression of Foxo1 and Foxo3 causes hypoglycemia and hyperlipidemia in mice. , 2012, Endocrinology.

[103]  Jiarui Wu,et al.  TNFα-induced up-regulation of miR-155 inhibits adipogenesis by down-regulating early adipogenic transcription factors. , 2011, Biochemical and biophysical research communications.

[104]  M. Zavolan,et al.  MicroRNAs 103 and 107 regulate insulin sensitivity , 2011, Nature.

[105]  R. McGregor,et al.  microRNAs in the Regulation of Adipogenesis and Obesity , 2011, Current molecular medicine.

[106]  L. Pastore,et al.  miR‐519d Overexpression Is Associated With Human Obesity , 2010, Obesity.

[107]  H. Soreq,et al.  MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase. , 2009, Immunity.

[108]  J. Orava,et al.  Functional brown adipose tissue in healthy adults. , 2009, The New England journal of medicine.

[109]  K. Waters,et al.  MicroRNA 132 regulates nutritional stress-induced chemokine production through repression of SirT1. , 2009, Molecular endocrinology.

[110]  Harvey F Lodish,et al.  Targeting microRNAs in obesity , 2009, Expert opinion on therapeutic targets.

[111]  M. Lutter,et al.  Homeostatic and hedonic signals interact in the regulation of food intake. , 2009, The Journal of nutrition.

[112]  H. Lodish,et al.  MicroRNAs Induced During Adipogenesis that Accelerate Fat Cell Development Are Downregulated in Obesity , 2009, Diabetes.

[113]  Tony Reiman,et al.  Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study. , 2008, The Lancet. Oncology.

[114]  É. Doucet,et al.  Methylphenidate Hydrochloride Increases Energy Expenditure in Healthy Adults , 2008, Obesity.

[115]  H. Berthoud,et al.  Eating for pleasure or calories. , 2007, Current opinion in pharmacology.

[116]  J. Brug,et al.  A systematic review of associations between environmental factors, energy and fat intakes among adults: is there evidence for environments that encourage obesogenic dietary intakes? , 2007, Public Health Nutrition.

[117]  S. O’Rahilly,et al.  Genetic factors in human obesity , 2007, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[118]  S. P. Nana-Sinkam,et al.  MicroRNA in lung cancer. , 2006, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

[119]  Mark Graham,et al.  miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. , 2006, Cell metabolism.

[120]  W. James,et al.  Effect of Plain Versus Sugar‐Sweetened Breakfast on Energy Balance and Metabolic Health: A Randomized Crossover Trial , 2020, Obesity.

[121]  R. Sherwin,et al.  Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[122]  J. Webber.  Energy balance in obesity , 2003, Proceedings of the Nutrition Society.

[123]  T. Pischon,et al.  Hypothesis: β-Adrenergic Receptor Blockers and Weight Gain , 2001 .

[124]  V. Ambros,et al.  The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14 , 1993, Cell.

[125]  A. H. Norris,et al.  Longitudinal changes in basal metabolism in man. , 1978, Journal of applied physiology: respiratory, environmental and exercise physiology.