Expression of SARS-CoV-2 Entry Factors in the Pancreas of Normal Organ Donors and Individuals with COVID-19

[1]  Diane C. Saunders,et al.  SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells , 2020, Cell Metabolism.

[2]  L. Prokunina-Olsson,et al.  Interferons and viruses induce a novel truncated ACE2 isoform and not the full-length SARS-CoV-2 receptor , 2020, Nature Genetics.

[3]  B. Obermayer,et al.  Human Lungs Show Limited Permissiveness for SARS-CoV-2 Due to Scarce ACE2 Levels But Strong Virus-Induced Immune Activation in Alveolar Macrophages , 2020, SSRN Electronic Journal.

[4]  The Lancet Diabetes & Endocrinology.  COVID-19 and diabetes: a co-conspiracy? , 2020, The Lancet Diabetes & Endocrinology.

[5]  D. Maahs,et al.  COVID-19 and Children With Diabetes—Updates, Unknowns, and Next Steps: First, Do No Extrapolation , 2020, Diabetes Care.

[6]  J. Rosenbauer,et al.  Did the COVID-19 Lockdown Affect the Incidence of Pediatric Type 1 Diabetes in Germany? , 2020, Diabetes Care.

[7]  N. Oliver,et al.  New-Onset Type 1 Diabetes in Children During COVID-19: Multicenter Regional Findings in the U.K. , 2020, Diabetes Care.

[8]  K. Khunti,et al.  Associations of type 1 and type 2 diabetes with COVID-19-related mortality in England: a whole-population study , 2020, The Lancet Diabetes & Endocrinology.

[9]  K. Khunti,et al.  Risk factors for COVID-19-related mortality in people with type 1 and type 2 diabetes in England: a population-based cohort study , 2020, The Lancet Diabetes & Endocrinology.

[10]  J. Skarbinski,et al.  Obesity and Mortality Among Patients Diagnosed With COVID-19: Results From an Integrated Health Care Organization , 2020, Annals of Internal Medicine.

[11]  J. Taneera,et al.  Expression Profile of SARS-CoV-2 Host Receptors in Human Pancreatic Islets Revealed Upregulation of ACE2 in Diabetic Donors , 2020, Biology.

[12]  D. Baralle,et al.  A novel isoform of ACE2 is expressed in human nasal and bronchial respiratory epithelia and is upregulated in response to RNA respiratory virus infection , 2020, bioRxiv.

[13]  Michael A. Joseph,et al.  The impact of obesity on COVID-19 complications: a retrospective cohort study , 2020, International Journal of Obesity.

[14]  Kevin W. Ng,et al.  Tissue-specific and interferon-inducible expression of non-functional ACE2 through endogenous retrovirus co-option , 2020, bioRxiv.

[15]  P. Marchetti,et al.  SARS-CoV-2 Receptor Angiotensin I-Converting Enzyme Type 2 (ACE2) Is Expressed in Human Pancreatic β-Cells and in the Human Pancreas Microvasculature , 2020, bioRxiv.

[16]  Z. Xia,et al.  Obesity and mortality of COVID-19. Meta-analysis , 2020, Obesity Research & Clinical Practice.

[17]  Colin Smith,et al.  Tissue-specific tolerance in fatal Covid-19 , 2020, medRxiv.

[18]  L. Marchand,et al.  Type 1 diabetes onset triggered by COVID-19 , 2020, Acta Diabetologica.

[19]  N. Goldman,et al.  High prevalence of COVID-19-associated diabetic ketoacidosis in UK secondary care , 2020, Diabetes Research and Clinical Practice.

[20]  S. Pittaluga,et al.  Megakaryocytes and platelet-fibrin thrombi characterize multi-organ thrombosis at autopsy in COVID-19: A case series , 2020, EClinicalMedicine.

[21]  Duc-Huy T. Nguyen,et al.  A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids , 2020, Cell Stem Cell.

[22]  R. V. Vander Heide,et al.  Pulmonary and cardiac pathology in African American patients with COVID-19: an autopsy series from New Orleans , 2020, The Lancet Respiratory Medicine.

[23]  Garry P. Nolan,et al.  Robust ACE2 protein expression localizes to the motile cilia of the respiratory tract epithelia and is not increased by ACE inhibitors or angiotensin receptor blockers , 2020, medRxiv.

[24]  M. Aepfelbacher,et al.  Autopsy Findings and Venous Thromboembolism in Patients With COVID-19 , 2020, Annals of Internal Medicine.

[25]  K. Mertz,et al.  Postmortem examination of COVID‐19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings in lungs and other organs suggesting vascular dysfunction , 2020, Histopathology.

[26]  F. Giorgi,et al.  Geographic and Genomic Distribution of SARS-CoV-2 Mutations , 2020, Frontiers in Microbiology.

[27]  J. Connors,et al.  COVID-19 and its implications for thrombosis and anticoagulation , 2020, Blood.

[28]  M. Diamond,et al.  TMPRSS2 and TMPRSS4 mediate SARS-CoV-2 infection of human small intestinal enterocytes , 2020, bioRxiv.

[29]  Holger Moch,et al.  Endothelial cell infection and endotheliitis in COVID-19 , 2020, The Lancet.

[30]  A. Maitra,et al.  Relative Abundance of SARS-CoV-2 Entry Genes in the Enterocytes of the Lower Gastrointestinal Tract , 2020, bioRxiv.

[31]  Guang Hao,et al.  The role of angiotensin-converting enzyme 2 in coronaviruses/influenza viruses and cardiovascular disease , 2020, Cardiovascular research.

[32]  C. Lindskog,et al.  The protein expression profile of ACE2 in human tissues , 2020, bioRxiv.

[33]  Qiu Zhao,et al.  Pancreatic Injury Patterns in Patients With Coronavirus Disease 19 Pneumonia , 2020, Gastroenterology.

[34]  Jian Chen,et al.  COVID‐19 infection may cause ketosis and ketoacidosis , 2020, Diabetes, obesity & metabolism.

[35]  B. Hanley,et al.  Autopsy in suspected COVID-19 cases , 2020, Journal of Clinical Pathology.

[36]  J. Xiang,et al.  Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study , 2020, The Lancet.

[37]  P. Liu,et al.  Gross examination report of a COVID-19 death autopsy. , 2020, Fa yi xue za zhi.

[38]  Paul Hoffman,et al.  Integrating single-cell transcriptomic data across different conditions, technologies, and species , 2018, Nature Biotechnology.

[39]  J. George,et al.  Single-cell transcriptomes identify human islet cell signatures and reveal cell-type–specific expression changes in type 2 diabetes , 2017, Genome research.

[40]  Samuel L. Wolock,et al.  A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure. , 2016, Cell systems.

[41]  Mauro J. Muraro,et al.  A Single-Cell Transcriptome Atlas of the Human Pancreas , 2016, Cell systems.

[42]  D. M. Smith,et al.  Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes , 2016, Cell metabolism.

[43]  Mauro J. Muraro,et al.  De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data , 2016, Cell stem cell.

[44]  E. Bonifacio,et al.  Validation of a rapid type 1 diabetes autoantibody screening assay for community‐based screening of organ donors to identify subjects at increased risk for the disease , 2016, Clinical and experimental immunology.

[45]  M. Atkinson,et al.  Network for Pancreatic Organ Donors with Diabetes (nPOD): developing a tissue biobank for type 1 diabetes , 2012, Diabetes/metabolism research and reviews.

[46]  Jin-Kui Yang,et al.  Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes , 2009, Acta Diabetologica.

[47]  Nigel M. Hooper,et al.  A Human Homolog of Angiotensin-converting Enzyme , 2000, The Journal of Biological Chemistry.

[48]  Diane C. Saunders,et al.  SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in b Cells , 2020 .