Brief Report: Cartilage Thickness Change as an Imaging Biomarker of Knee Osteoarthritis Progression: Data From the Foundation for the National Institutes of Health Osteoarthritis Biomarkers Consortium

To investigate the association of cartilage thickness change over 24 months, as determined by magnetic resonance imaging (MRI), with knee osteoarthritis (OA) progression at 24–48 months.

[1]  Felix Eckstein,et al.  Recent advances in osteoarthritis imaging—the Osteoarthritis Initiative , 2012, Nature Reviews Rheumatology.

[2]  B. Koes,et al.  Prognostic factors of progression of osteoarthritis of the knee: a systematic review of observational studies. , 2007, Arthritis and rheumatism.

[3]  J. Katz,et al.  Impact of Knee Osteoarthritis on Health Care Resource Utilization in a US Population-Based National Sample , 2010, Medical care.

[4]  J. Jordan,et al.  Lifetime Risk and Age at Diagnosis of Symptomatic Knee Osteoarthritis in the US , 2013, Arthritis care & research.

[5]  T. Spector,et al.  OARSI-OMERACT definition of relevant radiological progression in hip/knee osteoarthritis. , 2009, Osteoarthritis and cartilage.

[6]  F Eckstein,et al.  Using ordered values of subregional cartilage thickness change increases sensitivity in detecting risk factors for osteoarthritis progression. , 2011, Osteoarthritis and cartilage.

[7]  Felix Eckstein,et al.  Quantitative MRI measures of cartilage predict knee replacement: a case–control study from the Osteoarthritis Initiative , 2012, Annals of the rheumatic diseases.

[8]  F Angst,et al.  Smallest detectable and minimal clinically important differences of rehabilitation intervention with their implications for required sample sizes using WOMAC and SF-36 quality of life measurement instruments in patients with osteoarthritis of the lower extremities. , 2001, Arthritis and rheumatism.

[9]  F. Eckstein,et al.  Greater rates of cartilage loss in painful knees than in pain-free knees after adjustment for radiographic disease stage: data from the osteoarthritis initiative. , 2011, Arthritis and rheumatism.

[10]  F Eckstein,et al.  Imaging of cartilage and bone: promises and pitfalls in clinical trials of osteoarthritis. , 2014, Osteoarthritis and cartilage.

[11]  David Felson,et al.  Association between radiographic features of knee osteoarthritis and pain: results from two cohort studies , 2009, BMJ : British Medical Journal.

[12]  J. Katz,et al.  Trajectories and risk profiles of pain in persons with radiographic, symptomatic knee osteoarthritis: data from the osteoarthritis initiative. , 2014, Osteoarthritis and cartilage.

[13]  F Eckstein,et al.  Equivalence and precision of knee cartilage morphometry between different segmentation teams, cartilage regions, and MR acquisitions. , 2012, Osteoarthritis and cartilage.

[14]  M. Nevitt,et al.  Biomarkers for osteoarthritis: current position and steps towards further validation. , 2014, Best practice & research. Clinical rheumatology.

[15]  F. Eckstein,et al.  Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment--data from the Osteoarthritis Initiative. , 2014, Osteoarthritis and cartilage.