The use of PEEK as an occlusal splint in a patient with histaminosis: A case report

Abstract Poly‐(etheretherketone) (PEEK) began to be used in the field of odontology more than 10 years ago, especially in relation to the creation of removable partial dentures. Here we report the case of a 62 years old woman diagnosed with histamine intolerance (or histaminosis), who presented a very particular set of oral symptoms. She described a certain tingling, burning, and swelling of the mucous membranes. These symptoms seem to be linked with the wearing of a resin occlusal splint which was initially prescribed to compensate for the absence of a meniscus in the left temporomandibular joint of the patient. After a multidisciplinary concertation, it was decided to create a new splint with a resin‐free material. For this reason, the production of a PEEK prosthesis was considered. Following the installation of the occlusal splint in the patient, and after clinical adjustments, she described the occlusion positioning as correct and a disappearance of the symptomatology. Mechanically, PEEK seems to have higher mechanical resistance than PMMA. Despite these characteristics, the use of PEEK still presents some limitations, especially concerning the overall aesthetic. Additionally, the prescription of the occlusal splint seems to be limited to patients who need special care. The case presented here thus confirms a new perspective concerning the use of PEEK as an occlusal splint.

[1]  Rajani A Dable,et al.  Comparison of Mechanical Properties of PEEK and PMMA: An In Vitro Study. , 2021, The journal of contemporary dental practice.

[2]  Wenyan Zhao,et al.  Preliminary clinical evaluation of traditional and a new digital PEEK occlusal splints for the management of sleep bruxism. , 2020, Journal of oral rehabilitation.

[3]  M. Ferrari,et al.  The use of PEEK in digital prosthodontics: A narrative review , 2020, BMC oral health.

[4]  M. T. Veciana-Nogués,et al.  Histamine Intolerance: The Current State of the Art , 2020, Biomolecules.

[5]  M. Özcan,et al.  Surface roughness and wear behavior of occlusal splint materials made of contemporary and high-performance polymers , 2019, Odontology.

[6]  R. Asmatulu,et al.  Mechanical properties of highly porous PEEK bionanocomposites incorporated with carbon and hydroxyapatite nanoparticles for scaffold applications , 2019, Progress in Biomaterials.

[7]  P. Hatton,et al.  Determination of Polyetheretherketone (PEEK) mechanical properties as a denture material , 2019, The Saudi dental journal.

[8]  W. Schnedl,et al.  Non-celiac gluten sensitivity: people without celiac disease avoiding gluten—is it due to histamine intolerance? , 2017, Inflammation Research.

[9]  M. C. Vidal-Carou,et al.  Low serum diamine oxidase (DAO) activity levels in patients with migraine , 2018, Journal of Physiology and Biochemistry.

[10]  M. Wambacher,et al.  Allergic Reaction to Polyether Ether Ketone Following Cross-Reactivity to Epoxy Resin , 2017, Journal of cutaneous medicine and surgery.

[11]  Panagiotis Zoidis,et al.  The Use of a Modified Poly-Ether-Ether-Ketone (PEEK) as an Alternative Framework Material for Removable Dental Prostheses. A Clinical Report. , 2016, Journal of prosthodontics : official journal of the American College of Prosthodontists.

[12]  M. Rosentritt,et al.  Biofilm formation on the surface of modern implant abutment materials. , 2015, Clinical oral implants research.

[13]  Yanyan Zheng,et al.  Bone-like apatite coating on functionalized poly(etheretherketone) surface via tailored silanization layers technique. , 2015, Materials science & engineering. C, Materials for biological applications.

[14]  T. Buday,et al.  Histamine, histamine intoxication and intolerance. , 2015, Allergologia et immunopathologia.

[15]  Shoufeng Yang,et al.  A novel bioactive PEEK/HA composite with controlled 3D interconnected HA network , 2015 .

[16]  Andres L. Maldonado-Naranjo,et al.  Polyetheretherketone (PEEK) intervertebral cage as a cause of chronic systemic allergy: a case report. , 2015, The spine journal : official journal of the North American Spine Society.

[17]  A. Rusinek,et al.  Mechanical impact behavior of polyether–ether–ketone (PEEK) , 2015 .

[18]  Young-Jun Lim,et al.  Stress shielding and fatigue limits of poly-ether-ether-ketone dental implants. , 2012, Journal of biomedical materials research. Part B, Applied biomaterials.

[19]  S. Kurtz,et al.  Notch sensitivity of PEEK in monotonic tension. , 2009, Biomaterials.

[20]  J. Aschenbach,et al.  Bioelimination of histamine in epithelia of the porcine proximal colon of pigs , 2009, Inflammation Research.

[21]  N. Novak,et al.  Histamine and histamine intolerance. , 2007, The American journal of clinical nutrition.

[22]  F. Marcucci,et al.  The skin prick test. , 2018, Journal of biological regulators and homeostatic agents.

[23]  Juozas Žilinskas,et al.  PEEK polymer's properties and its use in prosthodontics. A review. , 2018, Stomatologija.

[24]  Juozas Žilinskas,et al.  A review of PEEK polymer's properties and its use in prosthodontics. , 2017, Stomatologija.

[25]  Muhammad Sohail Zafar,et al.  Applications of polyetheretherketone (PEEK) in oral implantology and prosthodontics. , 2016, Journal of prosthodontic research.