A Telemetric Pressure Sensor System for Biomedical Applications

A new implantable pressure sensor for long-term monitoring of intracranial pressure is presented. The sensor is powered by telemetry and can be interrogated wirelessly. A capacitive pressure transducer, whose capacitance is converted to a frequency-encoded signal by an application-specific integrated circuit (ASIC), senses the absolute pressure. The pressure-encoded signal, the ASIC input voltage, and onboard calibration parameters are transmitted to an external reading unit. The proposed novel packaging solution is designed for long-term stability and reliability of the sensor. The accuracy of sensor at body temperature is better than 2 mbar across a pressure range of 600-1200 mbar. The sensor is 13 mm in diameter and 4.5 mm in height.

[1]  E. Cosman,et al.  A telemetric pressure sensor for ventricular shunt systems. , 1979, Surgical neurology.

[2]  Horst Richter,et al.  Initial investigations on systems for measuring intraocular pressure , 2000 .

[3]  Robert Puers,et al.  Capacitive sensors: When and how to use them☆ , 1993 .

[4]  M. Dokmeci,et al.  Accelerated testing of anodically bonded glass-silicon packages in salt water , 1997, Proceedings of International Solid State Sensors and Actuators Conference (Transducers '97).

[5]  R E Baier,et al.  Thromboresistance of glass after glow discharge treatment in argon. , 1975, Journal of biomedical materials research.

[6]  G. W. Urbańczyk.  Molecular orientation in the amorphous fraction of poly(ethylene terephthalate) and polyamide 6 fibers , 1989 .

[7]  E. Cosman,et al.  A pressure-balanced radio-telemetry system for the measurement of intracranial pressure. A preliminary design report. , 1977, Journal of neurosurgery.

[8]  E. Schmidt,et al.  Long-term implants of Parylene-C coated microelectrodes , 2006, Medical and Biological Engineering and Computing.

[9]  S K Gautam,et al.  Is there a case for haemorheological screening in the haemocompatibility testing of materials? , 1995, Bio-medical materials and engineering.

[10]  M A Callahan,et al.  Conjunctivodacryocystorhinostomy: emplacement of the Jones Pyrex glass tube. , 1982, Transactions of the New Orleans Academy of Ophthalmology.

[11]  Paul Kremer,et al.  The scientific history of hydrocephalus and its treatment , 1999, Neurosurgical Review.

[12]  W. Mokwa,et al.  Surface micromachined pressure sensors with integrated CMOS read-out electronics , 1994 .

[13]  M Matsukawa,et al.  A new ventriculoperitoneal shunt with a telemetric intracranial pressure sensor: clinical experience in 94 patients with hydrocephalus. , 1997, Neurosurgery.

[14]  D. Edell,et al.  Biocompatibility of a silicon based peripheral nerve electrode. , 1982, Biomaterials, medical devices, and artificial organs.

[15]  Sung C. Choi,et al.  NINDS Traumatic Coma Data Bank: intracranial pressure monitoring methodology , 1991 .

[16]  R. Pudenz,et al.  The surgical treatment of hydrocephalus--an historical review. , 1981, Surgical neurology.

[17]  Andreas A Linninger,et al.  Pressure gradients in the brain in an experimental model of hydrocephalus. , 2005, Journal of neurosurgery.

[18]  J D Pickard,et al.  Laboratory testing of three intracranial pressure microtransducers: technical report. , 1996, Neurosurgery.

[19]  D. Wenzel,et al.  Low power integrated pressure sensor system for medical applications , 1999 .

[20]  R. Penn,et al.  Long-term testing of an intracranial pressure monitoring device. , 2000, Journal of neurosurgery.