Myoepithelioma of parotid gland presenting as infra‐auricular subcutaneous mass

Myoepithelioma is a rare but well‐characterized group of tumours, among which myoepithelioma of the salivary glands is the best known. We report two patients with myoepithelioma of parotid gland presenting as infra‐auricular subcutaneous mass. The lesions were clinically suspected to be epidermal cyst. The biopsies revealed that most of the tumour cells showed epithelioid features with oval or spindle eosinophilic cytoplasm. No ductal or syringomatous epithelial structures were observed. The tumour cells showed cytoplasmic immunoexpressions of vimentin, cytokeratin (AE1/AE3), S‐100 protein and smooth muscle actin (SMA). In one patient, a strong calponin positivity was observed. Maguetic resonance imaging (MRI) of both patients revealed exophytic, well‐defined, strongly enhancing mass in superficial lobe of parotid gland, confirming the parotid gland origin. Myoepithelioma of parotid gland can be presented as a slowly growing tumour of pre‐ or infra‐auricular area. In dermatologic department, it can be misdiagnosed as various dermal or subcutaneous tumours.

[1]  A. Kawada,et al.  Myoepithelioma Possibly Originating from the Accessory Parotid Gland , 2004, Dermatology.

[2]  C. Fletcher,et al.  Myoepithelial Tumors of Soft Tissue: A Clinicopathologic and Immunohistochemical Study of 101 Cases With Evaluation of Prognostic Parameters , 2003, The American journal of surgical pathology.

[3]  J. Shah,et al.  Head and Neck Surgery and Oncology , 2003 .

[4]  T. Mentzel,et al.  Cutaneous Myoepithelioma: An Under-Recognized Cutaneous Neoplasm Composed of Myoepithelial Cells , 2001, The American journal of surgical pathology.

[5]  A. Huvos,et al.  Myoepithelial carcinoma of the salivary glands: a clinicopathologic study of 25 patients. , 2000, The American journal of surgical pathology.

[6]  L. Alós,et al.  Myoepithelial tumors of salivary glands: a clinicopathologic, immunohistochemical, ultrastructural, and flow-cytometric study. , 1996, Seminars in diagnostic pathology.

[7]  I. Dardick Myoepithelioma: definitions and diagnostic criteria. , 1995, Ultrastructural pathology.

[8]  A. Sahin,et al.  Myoepithelioma of the retroperitoneum. , 1995, Ultrastructural pathology.

[9]  F. Tavassoli Myoepithelial Lesions of the Breast: Myoepitheliosis, Adenomyoepithelioma, and Myoepithelial Carcinoma , 1991, The American journal of surgical pathology.

[10]  D. J. Bird,et al.  Malignant myoepithelioma of the larynx with massive metastatic spread to the liver: an ultrastructural and immunocytochemical study. , 1991, Ultrastructural pathology.

[11]  I. Dardick,et al.  Myoepithelial cells in salivary gland tumors--revisited. , 1985, Head & neck surgery.

[12]  L. Barnes,et al.  Myoepitheliomas of the head and neck: Case report and review , 1985 .

[13]  J. Sciubba,et al.  Myoepithelioma of salivary glands: Report of 23 cases , 1982, Cancer.

[14]  I. Dardick,et al.  Histogenesis of salivary gland pleomorphic adenoma (mixed tumor) with an evaluation of the role of the myoepithelial cell. , 1982, Human pathology.