Alterations of hepatic ATP homeostasis and respiratory chain during development of non‐alcoholic steatohepatitis in a rodent model

Background  Mitochondrial dysfunction is considered a key player in non‐alcoholic steatohepatitis (NASH) but no data are available on the mitochondrial function and ATP homeostasis in the liver during NASH progression. In the present paper we evaluated the hepatic mitochondrial respiratory chain activity and ATP synthesis in a rodent model of NASH development.

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