MK-5204: An orally active β-1,3-glucan synthesis inhibitor.
暂无分享,去创建一个
P. Liberator | M. Motyl | M. Peel | J. Balkovec | Andrew M. Galgoci | C. Gill | R. Giacobbe | Weiming Fan | K. Nelson | Hao Liu | James M Apgar | R. Wilkening | D. Parker | D. Meng | K. J. Wildonger | D. Sperbeck | M. Greenlee | A. Flattery | G. Abruzzo | M. Hsu | A. Misura | M. Powles | F. Racine | J. Dragovic | R. Kirwan | Shuliang Lee | A. Mamai | J. N. Kahn | James M. Apgar
[1] T. Walsh,et al. Drugs currently under investigation for the treatment of invasive candidiasis , 2017, Expert opinion on investigational drugs.
[2] P. Liberator,et al. Novel orally active inhibitors of β-1,3-glucan synthesis derived from enfumafungin. , 2015, Bioorganic & medicinal chemistry letters.
[3] M. Arendrup,et al. Echinocandin resistance: an emerging clinical problem? , 2014, Current opinion in infectious diseases.
[4] B. Moriyama,et al. Emerging drugs and vaccines for Candidemia , 2014, Mycoses.
[5] K. Kerl,et al. Invasive candidiasis: update on current pharmacotherapy options and future perspectives , 2013, Expert opinion on pharmacotherapy.
[6] D. Perlin. Current perspectives on echinocandin class drugs. , 2011, Future microbiology.
[7] D. Denning,et al. Therapy for fungal diseases: opportunities and priorities. , 2010, Trends in microbiology.
[8] Ana Espinel-Ingroff,et al. Antifungal drug resistance mechanisms , 2009, Expert review of anti-infective therapy.
[9] M. Pfaller,et al. Epidemiology of Invasive Candidiasis: a Persistent Public Health Problem , 2007, Clinical Microbiology Reviews.
[10] N. Cosford,et al. Discovery of novel heteroarylazoles that are metabotropic glutamate subtype 5 receptor antagonists with anxiolytic activity. , 2004, Journal of medicinal chemistry.
[11] N. Wiederhold,et al. The echinocandin antifungals: an overview of the pharmacology, spectrum and clinical efficacy , 2003, Expert opinion on investigational drugs.
[12] N. Gow,et al. Antifungal agents: mechanisms of action. , 2003, Trends in microbiology.
[13] S. Volkman,et al. Asymmetric synthesis of protected 1,2-amino alcohols using tert-butanesulfinyl aldimines and ketimines. , 2001, The Journal of organic chemistry.
[14] Scott K. Smith,et al. Isolation and Structural Determination of Enfumafungin, a Triterpene Glycoside Antifungal Agent That Is a Specific Inhibitor of Glucan Synthesis , 2000 .
[15] R. Schwartz,et al. Discovery of Novel Antifungal (1,3)-β-d-Glucan Synthase Inhibitors , 2000, Antimicrobial Agents and Chemotherapy.
[16] J. Smith,et al. Evaluation of the echinocandin antifungal MK-0991 (L-743,872): efficacies in mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis , 1997, Antimicrobial agents and chemotherapy.
[17] D. Schmatz,et al. In vitro antifungal activities and in vivo efficacies of 1,3-beta-D-glucan synthesis inhibitors L-671,329, L-646,991, tetrahydroechinocandin B, and L-687,781, a papulacandin , 1992, Antimicrobial Agents and Chemotherapy.
[18] B. Kullberg,et al. Invasive Candidiasis. , 2015, The New England journal of medicine.
[19] M. Pfaller,et al. Antifungal drug resistance: mechanisms, epidemiology, and consequences for treatment. , 2012, The American journal of medicine.