QUESTION 4: Which patient-specific factors (i

RECOMMENDATION: There are currently no inflammatory arthritis-specific factors known to influence the thresholds for serum and synovial markers in PJIs. The literature on PJIs in inflammatory arthritis (IA) is sparse. While -defensin is the best studied synovial biomarker, as with synovial white blood cell (WBC) count and C-reactive protein (CRP), there appears to be overlap in values limiting their utility in differentiating septic from aseptic effusions in patients with inflammatory arthritis.

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