Improving Prescribing Safety in Patients with Renal Insufficiency in the Ambulatory Setting: The Drug Renal Alert Pharmacy (DRAP) Program

Study Objective. To determine whether a computerized Drug Renal Alert Pharmacy (DRAP) program could decrease the rate of medication errors in drug selection or dosing for 15 target drugs in patients with renal insufficiency.

[1]  R. Glasgow,et al.  Evaluating the public health impact of health promotion interventions: the RE-AIM framework. , 1999, American journal of public health.

[2]  M Wolfson,et al.  Drug prescribing in renal failure: dosing guidelines for adults. , 1983, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[3]  D. Bates,et al.  Guided medication dosing for inpatients with renal insufficiency. , 2001, JAMA.

[4]  Julia A. Kelleher,et al.  Improving laboratory monitoring at initiation of drug therapy in ambulatory care: a randomized trial. , 2005, Archives of internal medicine.

[5]  M. H. Gault,et al.  Prediction of creatinine clearance from serum creatinine. , 1975, Nephron.

[6]  Marsha A. Raebel,et al.  Research Paper: Randomized Trial to Improve Prescribing Safety During Pregnancy , 2007, J. Am. Medical Informatics Assoc..

[7]  P. Hebert,et al.  Reducing Excessive Medication Administration in Hospitalized Adults With Renal Dysfunction , 2005, American journal of medical quality : the official journal of the American College of Medical Quality.

[8]  Nikki M. Carroll,et al.  Randomized Trial to Improve Prescribing Safety in Ambulatory Elderly Patients , 2007, Journal of the American Geriatrics Society.

[9]  D. Magid,et al.  Imbedding Research in Practice to Improve Medication Safety , 2008 .

[10]  K. Hu,et al.  Calculation of the Estimated Creatinine Clearance in Avoiding Drug Dosing Errors in the Older Patient , 2001, The American journal of the medical sciences.

[11]  J. Heitman Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases , 2000 .

[12]  J. Kappel,et al.  Nephrology: 3. Safe drug prescribing for patients with renal insufficiency. , 2002, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

[13]  R. Frye,et al.  Drug Administration in Patients with Renal Insufficiency , 1997, Drug safety.

[14]  G. Matzke,et al.  Drug prescribing in renal failure: Dosing guidelines for adults , 1999 .

[15]  Richard Segal,et al.  Identifying clinically significant preventable adverse drug events through a hospital's database of adverse drug reaction reports. , 2002, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[16]  Eric Zapletal,et al.  Research Paper: Effect of Alerts for Drug Dosage Adjustment in Inpatients with Renal Insufficiency , 2009, J. Am. Medical Informatics Assoc..

[17]  John D. Storey A direct approach to false discovery rates , 2002 .

[18]  J. Coresh,et al.  Prevalence of chronic kidney disease in the United States. , 2007, JAMA.

[19]  S. Sheen,et al.  Overdose Rate of Drugs Requiring Renal Dose Adjustment: Data Analysis of 4 Years Prescriptions at a Tertiary Teaching Hospital , 2008, Journal of General Internal Medicine.

[20]  M. Bédard,et al.  Assessment of Adherence to Renal Dosing Guidelines in Long‐Term Care Facilities , 2000, Journal of the American Geriatrics Society.

[21]  Marsha A Raebel,et al.  Compliance with Dosing Guidelines in Patients with Chronic Kidney Disease , 2004, The Annals of pharmacotherapy.

[22]  R. Talbert Drug Dosing in Renal Insufficiency , 1994, Journal of clinical pharmacology.

[23]  E. Ellerbeck,et al.  Drug prescribing for patients with changing renal function. , 1992, American journal of hospital pharmacy.

[24]  W. Haefeli,et al.  Drug dosage in patients with renal failure optimized by immediate concurrent feedback , 2001, Journal of General Internal Medicine.

[25]  H. W. Jones,et al.  An analysis of discharge drug prescribing amongst elderly patients with renal impairment. , 1998, Postgraduate medical journal.

[26]  B. Brenner Brenner and Rector's The Kidney , 2000 .

[27]  D. Jeste,et al.  Metoclopramide-associated tardive dyskinesia. An analysis of 67 cases. , 1992, Archives of family medicine.

[28]  Mary Cooper,et al.  Impact of a computerized alert during physician order entry on medication dosing in patients with renal impairment , 2002, AMIA.

[29]  P. Pillans,et al.  Evaluation of dosage adjustment in patients with renal impairment , 2003, Internal medicine journal.

[30]  David Baker,et al.  Medication dosing errors for patients with renal insufficiency in ambulatory care. , 2005, Joint Commission journal on quality and patient safety.

[31]  Julia A. Kelleher,et al.  Randomized Trial to Improve Laboratory Safety Monitoring of Ongoing Drug Therapy in Ambulatory Patients , 2006, Pharmacotherapy.

[32]  William L. Galanter,et al.  Application of Information Technology: A Trial of Automated Decision Support Alerts for Contraindicated Medications Using Computerized Physician Order Entry , 2005, J. Am. Medical Informatics Assoc..

[33]  R. Talbert,et al.  Principles of Drug Administration in Renal Insufficiency , 1997, Clinical pharmacokinetics.

[34]  J. Kappel,et al.  Safe drug prescribing for patients with renal insufficiency , 2022 .

[35]  Thomas H. Payne,et al.  Review Paper: Medication-related Clinical Decision Support in Computerized Provider Order Entry Systems: A Review , 2007, J. Am. Medical Informatics Assoc..