Superparamagnetic iron oxide nanoparticles (SPIONs): development, surface modification and applications in chemotherapy.

[1]  G. G. Stokes "J." , 1890, The New Yale Book of Quotations.

[2]  Gebräuchliche Fertigarzneimittel,et al.  V , 1893, Therapielexikon Neurologie.

[3]  P. Meyers,et al.  EXPERIMENTAL APPROACH IN THE USE AND MAGNETIC CONTROL OF METALLIC IRON PARTICLES IN THE LYMPHATIC AND VASCULAR SYSTEM OF DOGS AS A CONTRAST AND ISOTOPIC AGENT. , 1963, The American journal of roentgenology, radium therapy, and nuclear medicine.

[4]  A. E. Nielsen Kinetics of precipitation , 1964 .

[5]  J F Alksne,et al.  Magnetically controlled metallic thrombosis of intracranial aneurysms. A preliminary report. , 1965, Bulletin of the Los Angeles neurological societies.

[6]  J. Alksne,et al.  Magnetically controlled metallic thrombosis of intracranial aneurysms , 1966 .

[7]  G. Miskolczy,et al.  Some applications of ferrofluid magnetic colloids , 1970 .

[8]  J. Bentson,et al.  Ferromagnetic silicone necrosis of hypernephromas by selective vascular occlusion to the tumor: a new technique. , 1975, The Journal of urology.

[9]  K. Widder,et al.  Magnetic guidance of drug‐carrying microspheres , 1978 .

[10]  K. Widder,et al.  Magnetic Microspheres: A Model System for Site Specific Drug Delivery in Vivo 1 , 1978, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[11]  Alan G. Walton,et al.  The Formation and Properties of Precipitates , 1979 .

[12]  K. Widder,et al.  Magnetically responsive microspheres and other carriers for the biophysical targeting of antitumor agents. , 1979, Advances in pharmacology and chemotherapy.

[13]  K Mosbach,et al.  Preparation and application of magnetic polymers for targeting of drugs , 1979, FEBS letters.

[14]  R. Chantrell,et al.  The magnetic properties and stability of a ferrofluid containing Fe3O4 particles , 1979 .

[15]  E. Matijević,et al.  Formation of uniform spherical magnetite particles by crystallization from ferrous hydroxide gels , 1980 .

[16]  R. Massart,et al.  Preparation of aqueous magnetic liquids in alkaline and acidic media , 1981 .

[17]  M. Fleet The structure of magnetite , 1981 .

[18]  K. Widder,et al.  In vivo kinetics of magnetically targeted low-dose doxorubicin. , 1981, Journal of pharmaceutical sciences.

[19]  E. R. Garrett,et al.  Prediction of stability in pharmaceutical preparations XVIII: application of high-pressure liquid chromatographic assays to study of nafronyl stability and bioanalysis. , 1981, Journal of pharmaceutical sciences.

[20]  K. Widder,et al.  Tumor remission in Yoshida sarcoma-bearing rts by selective targeting of magnetic albumin microspheres containing doxorubicin. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[21]  Oxygenation of ferrous ions in reversed micelle and reversed microemulsion , 1982 .

[22]  C. Breathnach Magnetism in medicine. , 1983, Irish medical journal.

[23]  K. Widder,et al.  Selective targeting of magnetic albumin microspheres containing low-dose doxorubicin: total remission in Yoshida sarcoma-bearing rats. , 1983, European journal of cancer & clinical oncology.

[24]  Particle size distributions and particle size alterations in microemulsions. , 1984, Journal of pharmaceutical sciences.

[25]  J. Pešička,et al.  The structure and low temperature strength of the age hardened Cu-Ni-Sn alloys , 1984 .

[26]  M. Homma,et al.  Magnetic microcapsules for targeted delivery of anticancer drugs. , 1984, Applied biochemistry and biotechnology.

[27]  P. Renshaw,et al.  Immunospecific NMR contrast agents. , 1986, Magnetic resonance imaging.

[28]  B. Künnecke,et al.  Monoclonal antibody‐coated magnetite particles as contrast agents in magnetic resonance imaging of tumors , 1989, Magnetic resonance in medicine.

[29]  Andreas Radbruch,et al.  High gradient magnetic cell separation with MACS. , 1990, Cytometry.

[30]  J. Bacri,et al.  Ionic ferrofluids: A crossing of chemistry and physics , 1990 .

[31]  R. Thompson,et al.  Analysis of the formation of monodisperse populations by homogeneous nucleation , 1991 .

[32]  C. Serna,et al.  The formation of a–Fe_2O_3 monodispersed particles in solution , 1992 .

[33]  Stefan Miltenyi,et al.  Specific MR imaging of human lymphocytes by monoclonal antibody‐guided dextran‐magnetite particles , 1992, Magnetic resonance in medicine.

[34]  J. Sunamoto,et al.  Recent aspects in the use of liposomes in biotechnology and medicine. , 1992, Progress in lipid research.

[35]  Ralph Weissleder,et al.  Colloidal magnetic resonance contrast agents : effect of particle surface on biodistribution , 1993 .

[36]  L. Illum,et al.  Influence of block copolymers on the adsorption of plasma proteins to microspheres. , 1993, Biomaterials.

[37]  H. Güntherodt,et al.  Charge freezing and surface anisotropy on magnetite (100) , 1993 .

[38]  K. Go,et al.  Our approach towards developing a specific tumour-targeted MRI contrast agent for the brain. , 1993, European journal of radiology.

[39]  R. Weissleder,et al.  MR Imaging of Slow Axonal Transport in Vivo , 1993, Experimental Neurology.

[40]  R Weissleder,et al.  MR imaging of the peripheral nervous system , 1994, Journal of magnetic resonance imaging : JMRI.

[41]  R. Weissleder,et al.  Pancreatic receptors: initial feasibility studies with a targeted contrast agent for MR imaging. , 1994, Radiology.

[42]  R Weissleder,et al.  Determinants of in vivo MR imaging of slow axonal transport. , 1994, Radiology.

[43]  Albert P. Philipse,et al.  Magnetic silica dispersions: preparation and stability of surface-modified silica particles with a magnetic core , 1994 .

[44]  V. Torchilin,et al.  In vivo visualizing of organs and tissues with liposomes , 1995 .

[45]  M. Shinkai,et al.  Antibody‐conjugated magnetoliposomes for targeting cancer cells and their application in hyperthermia , 1995, Biotechnology and applied biochemistry.

[46]  C. Serna,et al.  Uniform colloidal particles in solution: Formation mechanisms , 1995 .

[47]  J. Roger,et al.  Use of annexin V-ferrofluid to enumerate erythrocytes damaged in various pathologies or during storage in vitro. , 1995, Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie.

[48]  C Zimmer,et al.  MR imaging of neuronal transport in the guinea pig facial nerve: initial findings. , 1995, Acta oto-laryngologica.

[49]  P. Styring,et al.  Oligo(siloxane) rings and cages possessing nickel-containing liquid crystal side chains , 1996 .

[50]  R Weissleder,et al.  MR of carcinoma-specific monoclonal antibody conjugated to monocrystalline iron oxide nanoparticles: the potential for noninvasive diagnosis. , 1996, AJNR. American journal of neuroradiology.

[51]  Magnetic Characterization of Magnetite Particles for MR Contrast Agents , 1996 .

[52]  I. Lucet,et al.  Development of superparamagnetic nanoparticles for MRI: effect of particle size, charge and surface nature on biodistribution. , 1996, Journal of microencapsulation.

[53]  D. Huhn,et al.  Preclinical experiences with magnetic drug targeting: tolerance and efficacy. , 1996, Cancer research.

[54]  P Reichardt,et al.  Clinical experiences with magnetic drug targeting: a phase I study with 4'-epidoxorubicin in 14 patients with advanced solid tumors. , 1996, Cancer research.

[55]  Annexin V binding to mouse erythrocytes following infection with Plasmodium parasites. , 1996, Parasitology today.

[56]  M. Davies,et al.  Human serum albumin as a probe for protein adsorption to nanoparticles: relevance to biodistribution. , 1997, Journal of drug targeting.

[57]  A. Bée,et al.  Thiolation of Maghemite Nanoparticles by Dimercaptosuccinic Acid , 1997, Journal of colloid and interface science.

[58]  H. Buhr,et al.  Liposome-encapsulated superparamagnetic iron oxide particles as markers in an MRI-guided search for tumor-specific drug carriers. , 1997, Anti-cancer drug design.

[59]  C. N. Ramchand,et al.  Direct binding of protein to magnetic particles , 1997 .

[60]  J. Gallo,et al.  Enhanced brain tumor selectivity of cationic magnetic polysaccharide microspheres. , 1998, Journal of drug targeting.

[61]  R. Langer,et al.  Drug delivery and targeting. , 1998, Nature.

[62]  I. Saiki,et al.  Microdialysis assessment of 5-fluorouracil release from thermosensitive magnetoliposomes induced by an electromagnetic field in tumor-bearing mice. , 1998, Journal of drug targeting.

[63]  J. M. Harris,et al.  Novel degradable poly(ethylene glycol) hydrogels for controlled release of protein. , 1998, Journal of pharmaceutical sciences.

[64]  M. Kitajima,et al.  Magnetic resonance imaging of esophageal squamous cell carcinoma using magnetite particles coated with anti‐epidermal growth factor receptor antibody , 1998, International journal of cancer.

[65]  Sun,et al.  Surface Characteristics of Magnetite in Aqueous Suspension , 1998, Journal of colloid and interface science.

[66]  Carl K. Hoh,et al.  Targeting and retention of magnetic targeted carriers (MTCs) enhancing intra-arterial chemotherapy , 1999 .

[67]  J. Bacri,et al.  Some biomedical applications of ferrofluids , 1999 .

[68]  F. Favier,et al.  Electrochemical Synthesis for the Control of γ-Fe2O3 Nanoparticle Size. Morphology, Microstructure, and Magnetic Behavior , 1999 .

[69]  C. Bartolozzi,et al.  Abdominal MR: liver and pancreas , 1999, European Radiology.

[70]  Christian Bergemann,et al.  Physiological aspects in magnetic drug-targeting , 1999 .

[71]  Peter Kopčanský,et al.  Immobilization of proteins and enzymes to fine magnetic particles , 1999 .

[72]  C. Alexiou,et al.  Locoregional cancer treatment with magnetic drug targeting. , 2000, Cancer research.

[73]  T. Murakami,et al.  Targeted delivery of anticancer drugs with intravenously administered magnetic liposomes in osteosarcoma-bearing hamsters. , 2000, International journal of oncology.

[74]  A. Gedanken,et al.  Sonochemical synthesis and characterization of pure nanometer-sized Fe3O4 particles , 2000 .

[75]  S A Wickline,et al.  Magnetic resonance contrast enhancement of neovasculature with alpha(v)beta(3)-targeted nanoparticles. , 2000, Magnetic resonance in medicine.

[76]  Stasia A. Anderson,et al.  Magnetic resonance contrast enhancement of neovasculature with αvβ3‐targeted nanoparticles , 2000 .

[77]  Thomas de Quincey [C] , 2000, The Works of Thomas De Quincey, Vol. 1: Writings, 1799–1820.

[78]  R Weissleder,et al.  Improvement of MRI probes to allow efficient detection of gene expression. , 2000, Bioconjugate chemistry.

[79]  J. Tarascon,et al.  Nano-sized transition-metal oxides as negative-electrode materials for lithium-ion batteries , 2000, Nature.

[80]  C. Hurst,et al.  Application of magnetite and silica-magnetite composites to the isolation of genomic DNA. , 2000, Journal of chromatography. A.

[81]  C Alexiou,et al.  Clinical applications of magnetic drug targeting. , 2001, The Journal of surgical research.

[82]  D. Mooney,et al.  Polymeric system for dual growth factor delivery , 2001, Nature Biotechnology.

[83]  S M Moghimi,et al.  Long-circulating and target-specific nanoparticles: theory to practice. , 2001, Pharmacological reviews.

[84]  Mamoun Muhammed,et al.  Magnetic behavior of coated superparamagnetic iron oxide nanoparticles in ferrofluids , 2001 .

[85]  A. Gedanken,et al.  Fabrication of magnetite nanorods by ultrasound irradiation , 2001 .

[86]  P. Morais,et al.  Magnetic resonance of a dextran-coated magnetic fluid intravenously administered in mice. , 2001, Biophysical journal.

[87]  U. Häfeli Radioactive Microspheres for Medical Applications , 2001 .

[88]  Ming Zhao,et al.  Non-invasive detection of apoptosis using magnetic resonance imaging and a targeted contrast agent , 2001, Nature Medicine.

[89]  S. A. Gómez-Lopera,et al.  Synthesis and Characterization of Spherical Magnetite/Biodegradable Polymer Composite Particles. , 2001, Journal of colloid and interface science.

[90]  O. Mykhaylyk,et al.  Glial brain tumor targeting of magnetite nanoparticles in rats , 2001 .

[91]  J. Koda,et al.  Adsorption and desorption of chemotherapeutic drugs from a magnetically targeted carrier (MTC). , 2001, Journal of controlled release : official journal of the Controlled Release Society.

[92]  S. Goodwin,et al.  Single-dose toxicity study of hepatic intra-arterial infusion of doxorubicin coupled to a novel magnetically targeted drug carrier. , 2001, Toxicological sciences : an official journal of the Society of Toxicology.

[93]  In-situ Gold Coating of Superparamagnetic Nanoparticles by Microemulsion Method , 2001 .

[94]  H. Pizem,et al.  Alkyl Phosphonate/Phosphate Coating on Magnetite Nanoparticles: A Comparison with Fatty Acids , 2001 .

[95]  T. Murakami,et al.  Targeted systemic chemotherapy using magnetic liposomes with incorporated adriamycin for osteosarcoma in hamsters. , 2001, International journal of oncology.

[96]  Elizabeth Kim Race Sells , 2002 .

[97]  P. Gupta,et al.  Hydrogels: from controlled release to pH-responsive drug delivery. , 2002, Drug discovery today.

[98]  Erkki Ruoslahti,et al.  Nanocrystal targeting in vivo , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[99]  Monica Soncini,et al.  Experimental procedure for the evaluation of the mechanical properties of the bone surrounding dental implants. , 2002, Biomaterials.

[100]  P A Voltairas,et al.  Hydrodynamics of magnetic drug targeting. , 2002, Journal of biomechanics.

[101]  Structural and magnetic transformation of monodispersed iron oxide particles in a reducing atmosphere , 2002 .

[102]  Jeff W. M. Bulte,et al.  Physics and Chemistry Basis of Biotechnology , 2002, Focus on Biotechnology.

[103]  Hao Zeng,et al.  Size-controlled synthesis of magnetite nanoparticles. , 2002, Journal of the American Chemical Society.

[104]  S. Prabhakar,et al.  Synthesis of gamma ferric oxide by direct thermal decomposition of ferrous carbonate , 2002 .

[105]  S. B. Deshpande,et al.  Microwave hydrothermal preparation of submicron-sized spherical magnetite (Fe3O4) powders , 2002 .

[106]  Ralph Weissleder,et al.  Annexin V–CLIO: A Nanoparticle for Detecting Apoptosis by MRI , 2002, Molecular imaging.

[107]  A. Philipse,et al.  Magnetic Colloids from Magnetotactic Bacteria: Chain Formation and Colloidal Stability , 2002 .

[108]  S. Musić,et al.  Formation of nanocrystalline magnetite by thermal decomposition of iron choline citrate , 2002 .

[109]  P. Babinec,et al.  AC-magnetic field controlled drug release from magnetoliposomes: design of a method for site-specific chemotherapy. , 2002, Bioelectrochemistry.

[110]  Direct binding procedure of proteins and enzymes to fine magnetic particles , 2002 .

[111]  Nathan Kohler,et al.  Surface modification of superparamagnetic magnetite nanoparticles and their intracellular uptake. , 2002, Biomaterials.

[112]  Alexander Petrovsky,et al.  Magnetic resonance imaging of inducible E-selectin expression in human endothelial cell culture. , 2002, Bioconjugate chemistry.

[113]  Thomas Wisniewski,et al.  Detection of Alzheimer's amyloid in transgenic mice using magnetic resonance microimaging , 2003, Magnetic resonance in medicine.

[114]  H. Hofmann,et al.  Superparamagnetic Iron Oxide Nanoarticles for Biomedical Applications: a focus on PVA as a coating , 2003 .

[115]  A. ADoefaa,et al.  ? ? ? ? f ? ? ? ? ? , 2003 .

[116]  C. Serna,et al.  Synthesis of monodisperse superparamagnetic Fe/silica nanospherical composites. , 2003, Journal of the American Chemical Society.

[117]  Neil D. Mathur,et al.  Magnetic Materials: Fundamentals and Device Applications , 2003 .

[118]  Ralph Weissleder,et al.  A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperative optical brain tumor delineation. , 2003, Cancer research.

[119]  Robert Langer,et al.  Small-scale systems for in vivo drug delivery , 2003, Nature Biotechnology.

[120]  R. Weissleder,et al.  The transferrin receptor: a potential molecular imaging marker for human cancer. , 2003, Neoplasia.

[121]  G. Stucky,et al.  Cooperative Assembly of Magnetic Nanoparticles and Block Copolypeptides in Aqueous Media , 2003 .

[122]  M. Saunders,et al.  Magnetite Nanoparticle Dispersions Stabilized with Triblock Copolymers , 2003 .

[123]  H. Itoh,et al.  Systematic control of size, shape, structure, and magnetic properties of uniform magnetite and maghemite particles. , 2003, Journal of colloid and interface science.

[124]  I. Hamley,et al.  Nanotechnology with soft materials. , 2003, Angewandte Chemie.

[125]  Hong Yang,et al.  “Pulling” Nanoparticles into Water: Phase Transfer of Oleic Acid Stabilized Monodisperse Nanoparticles into Aqueous Solutions of α-Cyclodextrin , 2003 .

[126]  Yu Zhang,et al.  Starch-Coated Superparamagnetic Nanoparticles as MR Contrast Agents , 2003 .

[127]  J. M. Harris,et al.  Effect of pegylation on pharmaceuticals , 2003, Nature Reviews Drug Discovery.

[128]  Yong Wang,et al.  Solvent-Free Atom Transfer Radical Polymerization in the Synthesis of Fe2O3@Polystyrene Core−Shell Nanoparticles , 2003 .

[129]  Identification and quantitation of extractables from cellulose acetate butyrate (CAB) and estimation of their in vivo exposure levels. , 2004, Journal of pharmaceutical and biomedical analysis.

[130]  Aaron J. Johnson,et al.  In vivo magnetic resonance imaging of immune cells in the central nervous system with superparamagnetic antibodies , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[131]  Ralph Weissleder,et al.  Magneto/optical annexin V, a multimodal protein. , 2004, Bioconjugate chemistry.

[132]  A. Gupta,et al.  Surface-modified superparamagnetic nanoparticles for drug delivery: preparation, characterization, and cytotoxicity studies , 2004, IEEE Transactions on NanoBioscience.

[133]  Michael Todd,et al.  Synthesis, characterisation and application of silica-magnetite nanocomposites , 2004 .

[134]  Cross-linking the Linear Polymeric Chains in the ATRP Synthesis of Iron Oxide/Polystyrene Core/Shell Nanoparticles , 2004 .

[135]  U. Häfeli,et al.  Magnetizable needles and wires--modeling an efficient way to target magnetic microspheres in vivo. , 2004, Biorheology.

[136]  C. Hoeller,et al.  MR imaging of the her2/neu and 9.2.27 tumor antigens using immunospecific contrast agents. , 2004, Magnetic resonance imaging.

[137]  Thomas Walz,et al.  Structure of the Human Transferrin Receptor-Transferrin Complex , 2004, Cell.

[138]  William W. Yu,et al.  Synthesis of monodisperse iron oxide nanocrystals by thermal decomposition of iron carboxylate salts. , 2004, Chemical communications.

[139]  J. Gallo,et al.  Distribution of Small Magnetic Particles in Brain Tumor-bearing Rats , 2004, Journal of Neuro-Oncology.

[140]  J. A. Ritter,et al.  Analysis of magnetic drug carrier particle capture by a magnetizable intravascular stent: 1. Parametric study with single wire correlation , 2004 .

[141]  Joachim O. Rädler,et al.  Hydrophobic Nanocrystals Coated with an Amphiphilic Polymer Shell: A General Route to Water Soluble Nanocrystals , 2004 .

[142]  Armin D. Ebner,et al.  Application of high gradient magnetic separation principles to magnetic drug targeting , 2004 .

[143]  Keliang Liu,et al.  Fe3O4 Nanoparticles coated with homopolymers of glycerol mono(meth)acrylate and their block copolymers , 2005 .

[144]  Armin D. Ebner,et al.  Magnetizable implants and functionalized magnetic carriers: A novel approach for noninvasive yet targeted drug delivery , 2005 .

[145]  Lee Hai Bang,et al.  Preparation of Poly(vinylpyrrolidone) Coated Iron Oxide Nanoparticles for Contrast Agent , 2005 .

[146]  Qianwang Chen,et al.  Synthesis of Magnetite Nanorods through Reduction of β-FeOOH , 2005 .

[147]  Armin D. Ebner,et al.  Analysis of magnetic drug carrier particle capture by a magnetizable intravascular stent—2: Parametric study with multi-wire two-dimensional model , 2005 .

[148]  Ralph Weissleder,et al.  Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto‐optical nanoparticle , 2005, Magnetic resonance in medicine.

[149]  Ludmila Buzhansky,et al.  Magnetically responsive carboxylated magnetite-polydipyrrole/polydicarbazole nanocomposites of core-shell morphology. Preparation, characterization, and use in DNA hybridization. , 2005, Journal of the American Chemical Society.

[150]  H. Hofmann,et al.  Superparamagnetic nanoparticles for biomedical applications: Possibilities and limitations of a new drug delivery system , 2005 .

[151]  Armin D. Ebner,et al.  Theoretical analysis of a transdermal ferromagnetic implant for retention of magnetic drug carrier particles , 2005 .

[152]  Mingyuan Gao,et al.  One‐Pot Reaction to Synthesize Biocompatible Magnetite Nanoparticles , 2005 .

[153]  Tapas Sen,et al.  Multifunctional magnetite and silica–magnetite nanoparticles: Synthesis, surface activation and applications in life sciences , 2005 .

[154]  Kenneth A. Barbee,et al.  Targeted drug delivery to magnetic implants for therapeutic applications , 2005 .

[155]  Norval J. C. Strachan,et al.  Modelling magnetic carrier particle targeting in the tumor microvasculature for cancer treatment , 2005 .

[156]  Jinwoo Cheon,et al.  Nanoscale size effect of magnetic nanocrystals and their utilization for cancer diagnosis via magnetic resonance imaging. , 2005, Journal of the American Chemical Society.

[157]  Sang Bok Lee,et al.  Magnetic nanotubes for magnetic-field-assisted bioseparation, biointeraction, and drug delivery. , 2005, Journal of the American Chemical Society.

[158]  S. Laurent,et al.  C-MALISA (cellular magnetic-linked immunosorbent assay), a new application of cellular ELISA for MRI. , 2005, Journal of inorganic biochemistry.

[159]  K. Krishnan,et al.  Synthesis of magnetoliposomes with monodisperse iron oxide nanocrystal cores for hyperthermia , 2005 .

[160]  Jin-Sil Choi,et al.  In vivo magnetic resonance detection of cancer by using multifunctional magnetic nanocrystals. , 2005, Journal of the American Chemical Society.

[161]  D. Leslie-Pelecky,et al.  Iron oxide nanoparticles for sustained delivery of anticancer agents. , 2005, Molecular pharmaceutics.

[162]  Ajay Kumar Gupta,et al.  Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. , 2005, Biomaterials.

[163]  R. Weissleder,et al.  In vivo imaging of activated endothelium using an anti-VCAM-1 magnetooptical probe. , 2005, Bioconjugate chemistry.

[164]  Taeghwan Hyeon,et al.  Large‐Scale Synthesis of Uniform and Crystalline Magnetite Nanoparticles Using Reverse Micelles as Nanoreactors under Reflux Conditions , 2005 .

[165]  Giles Richardson,et al.  Mathematical modelling of magnetically targeted drug delivery , 2005 .

[166]  Tapas Sen,et al.  Surface modification of magnetic nanoparticles with alkoxysilanes and their application in magnetic bioseparations. , 2005, Langmuir : the ACS journal of surfaces and colloids.

[167]  Kai Qi,et al.  64Cu-labeled folate-conjugated shell cross-linked nanoparticles for tumor imaging and radiotherapy: synthesis, radiolabeling, and biologic evaluation. , 2005, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[168]  John M Pauly,et al.  Positive contrast magnetic resonance imaging of cells labeled with magnetic nanoparticles , 2005, Magnetic resonance in medicine.

[169]  J. Dobson Magnetic nanoparticles for drug delivery , 2006 .

[170]  Do Kyung Kim,et al.  Antibiofouling polymer-coated superparamagnetic iron oxide nanoparticles as potential magnetic resonance contrast agents for in vivo cancer imaging. , 2006, Journal of the American Chemical Society.

[171]  C. Chiang,et al.  Application of silica–magnetite nanocomposites to the isolation of ultrapure plasmid DNA from bacterial cells , 2006 .

[172]  A. Khademhosseini,et al.  Hydrogels in Biology and Medicine: From Molecular Principles to Bionanotechnology , 2006 .

[173]  E P Furlani,et al.  Analytical model of magnetic nanoparticle transport and capture in the microvasculature. , 2006, Physical review. E, Statistical, nonlinear, and soft matter physics.

[174]  T. Sen,et al.  Mesoporous silica-magnetite nanocomposite: fabrication and applications in magnetic bioseparations. , 2006, Journal of the American Chemical Society.

[175]  Hua Ai,et al.  Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems. , 2006, Nano letters.

[176]  Xavier Montet,et al.  Interaction of Functionalized Superparamagnetic Iron Oxide Nanoparticles with Brain Structures , 2006, Journal of Pharmacology and Experimental Therapeutics.

[177]  Yang-Chuang Chang,et al.  Recovery of gold(III) ions by a chitosancoated magnetic nano-adsorbent , 2006 .

[178]  S. Laurent,et al.  Specific E-selectin targeting with a superparamagnetic MRI contrast agent. , 2006, Contrast media & molecular imaging.

[179]  Ralph Weissleder,et al.  A fluorescent nanosensor for apoptotic cells. , 2006, Nano letters.

[180]  R. Weissleder,et al.  Imaging pancreatic cancer with a peptide-nanoparticle conjugate targeted to normal pancreas. , 2006, Bioconjugate chemistry.

[181]  U Teichgräber,et al.  Magnetite-loaded carrier erythrocytes as contrast agents for magnetic resonance imaging. , 2006, Nano letters.

[182]  S. Magdassi,et al.  Dispersion of magnetic nanoparticles in suspension , 2006 .

[183]  P. Lesný,et al.  Bone Marrow Stem Cells and Polymer Hydrogels—Two Strategies for Spinal Cord Injury Repair , 2006, Cellular and Molecular Neurobiology.

[184]  Indranil Sarkar,et al.  Extracellular biosynthesis of magnetite using fungi. , 2006, Small.

[185]  T. Xia,et al.  Toxic Potential of Materials at the Nanolevel , 2006, Science.

[186]  W. Eccleston,et al.  Mater. Res. Soc. Symp. Proc. , 2006 .

[187]  Ande Bao,et al.  Potential use of drug carried-liposomes for cancer therapy via direct intratumoral injection. , 2006, International journal of pharmaceutics.

[188]  Armin D. Ebner,et al.  In vitro study of ferromagnetic stents for implant assisted-magnetic drug targeting , 2007 .

[189]  Sara Linse,et al.  Understanding the nanoparticle–protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles , 2007, Proceedings of the National Academy of Sciences.

[190]  Ajay Kumar Gupta,et al.  Recent advances on surface engineering of magnetic iron oxide nanoparticles and their biomedical applications. , 2007, Nanomedicine.

[191]  B. H. An,et al.  One-pot polyol synthesis of monosize PVP-coated sub-5 nm Fe3O4 nanoparticles for biomedical applications , 2007 .

[192]  Benjamin R. Jarrett,et al.  Size-controlled synthesis of dextran sulfate coated iron oxide nanoparticles for magnetic resonance imaging , 2007, Nanotechnology.

[193]  Sara Linse,et al.  The nanoparticle-protein complex as a biological entity; a complex fluids and surface science challenge for the 21st century. , 2007, Advances in colloid and interface science.

[194]  Sangjin Park,et al.  Thermally cross-linked superparamagnetic iron oxide nanoparticles: synthesis and application as a dual imaging probe for cancer in vivo. , 2007, Journal of the American Chemical Society.

[195]  E. Fama,et al.  Migration , 2007 .

[196]  R. Weissleder,et al.  Targeted delivery of multifunctional magnetic nanoparticles. , 2007, Nanomedicine.

[197]  P. Jendelová,et al.  Migration, fate and in vivo imaging of adult stem cells in the CNS , 2007, Cell Death and Differentiation.

[198]  Jinwoo Cheon,et al.  Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging , 2007, Nature Medicine.

[199]  Wolfhard Semmler,et al.  Specific targeting of tumor angiogenesis by RGD-conjugated ultrasmall superparamagnetic iron oxide particles using a clinical 1.5-T magnetic resonance scanner. , 2007, Cancer research.

[200]  Iseult Lynch,et al.  Are there generic mechanisms governing interactions between nanoparticles and cells? Epitope mapping the outer layer of the protein-material interface , 2007 .

[201]  I. Chourpa,et al.  Nanovectors for anticancer agents based on superparamagnetic iron oxide nanoparticles , 2007, International journal of nanomedicine.

[202]  Pallab Pradhan,et al.  Preparation and characterization of manganese ferrite-based magnetic liposomes for hyperthermia treatment of cancer , 2007 .

[203]  Shin-ichi Takeda,et al.  Development of magnetically targeted drug delivery system using superconducting magnet , 2007 .

[204]  Application of Dextran Coated Magnetic Iron Oxide Nanoparticles in Delivering Target Gene into Cells in Vitro , 2007 .

[205]  Atsushi Arakaki,et al.  Controlled formation of magnetite crystal by partial oxidation of ferrous hydroxide in the presence of recombinant magnetotactic bacterial protein Mms6. , 2007, Biomaterials.

[206]  I. Bravo-Osuna,et al.  Tuning of shell and core characteristics of chitosan-decorated acrylic nanoparticles. , 2007, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[207]  M. Shoichet,et al.  Peptide surface modification of methacrylamide chitosan for neural tissue engineering applications. , 2007, Journal of biomedical materials research. Part A.

[208]  B. Narasimhan,et al.  Protein‐Mediated Synthesis of Uniform Superparamagnetic Magnetite Nanocrystals , 2007 .

[209]  S. Nishijima,et al.  Development of Magnetic Field Control for Magnetically Targeted Drug Delivery System Using a Superconducting Magnet , 2007, IEEE Transactions on Applied Superconductivity.

[210]  H. Iseki,et al.  A Study of Magnetic Drug Delivery System Using Bulk High Temperature Superconducting Magnet , 2008, IEEE Transactions on Applied Superconductivity.

[211]  S. Dutz,et al.  Effects of size distribution on hysteresis losses of magnetic nanoparticles for hyperthermia , 2008, Journal of physics. Condensed matter : an Institute of Physics journal.

[212]  J. Dobson,et al.  Development of Superparamagnetic Iron Oxide Nanoparticles (SPIONS) for Translation to Clinical Applications , 2008, IEEE Transactions on NanoBioscience.

[213]  Chris A Flask,et al.  Magnetic nanoparticles with dual functional properties: drug delivery and magnetic resonance imaging. , 2008, Biomaterials.

[214]  Jianlin Shi,et al.  Uniform Rattle‐type Hollow Magnetic Mesoporous Spheres as Drug Delivery Carriers and their Sustained‐Release Property , 2008 .

[215]  M. Takano,et al.  Large-scale synthesis of single-crystalline iron oxide magnetic nanorings. , 2008, Journal of the American Chemical Society.

[216]  Gregory Fridman,et al.  Validation of High Gradient Magnetic Field Based Drug Delivery to Magnetizable Implants Under Flow , 2008, IEEE Transactions on Biomedical Engineering.

[217]  A Novel Method to Synthesize Monodispersed Magnetite Nanoparticles , 2008 .

[218]  Ralph Weissleder,et al.  Multifunctional magnetic nanoparticles for targeted imaging and therapy. , 2008, Advanced drug delivery reviews.

[219]  S. Ogale,et al.  Bacteria-mediated precursor-dependent biosynthesis of superparamagnetic iron oxide and iron sulfide nanoparticles. , 2008, Langmuir : the ACS journal of surfaces and colloids.

[220]  Jing Sun,et al.  Preparation and characterization of interferon-loaded magnetic biodegradable microspheres. , 2008, Journal of biomedical materials research. Part B, Applied biomaterials.

[221]  Yoshio Kobayashi,et al.  Preparation of composite particles with magnetic silica core and fluorescent polymer shell , 2008 .

[222]  Donghoon Lee,et al.  In vivo MRI detection of gliomas by chlorotoxin-conjugated superparamagnetic nanoprobes. , 2008, Small.

[223]  C. Robic,et al.  Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications. , 2008, Chemical reviews.

[224]  E. Kossel,et al.  Iron oxide-loaded liposomes for MR imaging. , 2008, Frontiers in bioscience : a journal and virtual library.

[225]  G. Jiang,et al.  Preparation of silica-magnetite nanoparticle mixed hemimicelle sorbents for extraction of several typical phenolic compounds from environmental water samples. , 2008, Journal of chromatography. A.

[226]  H. Karlsson,et al.  Copper oxide nanoparticles are highly toxic: a comparison between metal oxide nanoparticles and carbon nanotubes. , 2008, Chemical research in toxicology.

[227]  Taeghwan Hyeon,et al.  Multifunctional uniform nanoparticles composed of a magnetite nanocrystal core and a mesoporous silica shell for magnetic resonance and fluorescence imaging and for drug delivery. , 2008, Angewandte Chemie.

[228]  I. Bruce,et al.  Extraction of DNA from soil using nanoparticles by magnetic bioseparation , 2008, Letters in applied microbiology.

[229]  M. Magnani,et al.  New biomimetic constructs for improved in vivo circulation of superparamagnetic nanoparticles. , 2008, Journal of nanoscience and nanotechnology.

[230]  Dongen Zhang,et al.  Fabrication and characterization of hollow Fe3O4 nanospheres in a microemulsion , 2008 .

[231]  Morteza Mahmoudi,et al.  Optimal design and characterization of superparamagnetic iron oxide nanoparticles coated with polyvinyl alcohol for targeted delivery and imaging. , 2008, The journal of physical chemistry. B.

[232]  Hong Xu,et al.  Superparamagnetic magnetite nanocrystal clusters: a sensitive tool for MR cellular imaging , 2009, Nanotechnology.

[233]  Xiuqing Gong,et al.  Design and Fabrication of Magnetically Functionalized Core/Shell Microspheres for Smart Drug Delivery , 2009 .

[234]  T. Hyeon,et al.  Multifunctional nanostructured materials for multimodal imaging, and simultaneous imaging and therapy. , 2009, Chemical Society reviews.

[235]  P Stroeve,et al.  Cell toxicity of superparamagnetic iron oxide nanoparticles. , 2009, Journal of colloid and interface science.

[236]  C. Gabay,et al.  Magnetically retainable microparticles for drug delivery to the joint: efficacy studies in an antigen-induced arthritis model in mice , 2009, Arthritis research & therapy.

[237]  J. Ardisson,et al.  Study of mesoporous silica/magnetite systems in drug controlled release , 2009, Journal of materials science. Materials in medicine.

[238]  A. Teja,et al.  Synthesis, properties, and applications of magnetic iron oxide nanoparticles , 2009 .

[239]  Mu-Yi Hua,et al.  Magnetically targeted thrombolysis with recombinant tissue plasminogen activator bound to polyacrylic acid-coated nanoparticles. , 2009, Biomaterials.

[240]  Gary Friedman,et al.  Magnetic targeting for site-specific drug delivery: applications and clinical potential. , 2009, Expert opinion on drug delivery.

[241]  H. Vali,et al.  Cytotoxicity and Cell Cycle Effects of Bare and Poly(vinyl alcohol)‐Coated Iron Oxide Nanoparticles in Mouse Fibroblasts , 2009 .

[242]  Taeghwan Hyeon,et al.  Synthesis of uniform ferrimagnetic magnetite nanocubes. , 2009, Journal of the American Chemical Society.

[243]  E. Wang,et al.  Monodisperse mesoporous superparamagnetic single-crystal magnetite nanoparticles for drug delivery. , 2009, Biomaterials.

[244]  T. Sen,et al.  Mesoporous silica–magnetite nanocomposites: Fabrication, characterisation and applications in biosciences , 2009 .

[245]  Morteza Mahmoudi,et al.  An in vitro study of bare and poly(ethylene glycol)-co-fumarate-coated superparamagnetic iron oxide nanoparticles: a new toxicity identification procedure , 2009, Nanotechnology.

[246]  Abbas S. Milani,et al.  Multiphysics Flow Modeling and in Vitro Toxicity of Iron Oxide Nanoparticles Coated with Poly(vinyl alcohol) , 2009 .

[247]  S. Intorasoot,et al.  Application of gelatin-coated magnetic particles for isolation of genomic DNA from bacterial cells. , 2009, Analytical biochemistry.

[248]  Stephen R Quake,et al.  An in vitro microfluidic approach to generating protein-interaction networks , 2009, Nature Methods.

[249]  J. Frank,et al.  In Vivo Cellular Imaging for Translational Medical Research. , 2009, Current medical imaging reviews.

[250]  Taeghwan Hyeon,et al.  Multifunctional nanostructured materials for multimodal imaging, and simultaneous imaging and therapy. , 2009, Chemical Society reviews.

[251]  S. Dai,et al.  Polysaccharide surface modified Fe3O4 nanoparticles for camptothecin loading and release. , 2009, Acta biomaterialia.

[252]  Jan Grimm,et al.  Drug/dye-loaded, multifunctional iron oxide nanoparticles for combined targeted cancer therapy and dual optical/magnetic resonance imaging. , 2009, Small.

[253]  M. Mahmoudi,et al.  Superparamagnetic Iron Oxide Nanoparticles with Rigid Cross-linked Polyethylene Glycol Fumarate Coating for Application in Imaging and Drug Delivery , 2009 .

[254]  Research and Development of Magnetic Drug Delivery System Using Bulk High Temperature Superconducting Magnet , 2009, IEEE Transactions on Applied Superconductivity.

[255]  Xianming Liu,et al.  Solvothermal synthesis and magnetic properties of magnetite nanoplatelets , 2009 .

[256]  S. Tie,et al.  Mesoporous silica-coated superparamagnetic magnetite functionalized with CuO and its application as a desulfurizer , 2009 .

[257]  M. Mahmoudi,et al.  Preparation and biological evaluation of [67Ga]-labeled-superparamagnetic nanoparticles in normal rats , 2009 .

[258]  J. Ding,et al.  Synthesis of magnetite nanoparticles via a solvent-free thermal decomposition route , 2009 .

[259]  J. Lloyd,et al.  Harnessing the extracellular bacterial production of nanoscale cobalt ferrite with exploitable magnetic properties. , 2009, ACS nano.

[260]  Tetsuya Osaka,et al.  Effect of surface charge of magnetite nanoparticles on their internalization into breast cancer and umbilical vein endothelial cells. , 2009, Colloids and surfaces. B, Biointerfaces.

[261]  Peter R Seevinck,et al.  Superparamagnetic iron oxide nanoparticles encapsulated in biodegradable thermosensitive polymeric micelles: toward a targeted nanomedicine suitable for image-guided drug delivery. , 2009, Langmuir : the ACS journal of surfaces and colloids.

[262]  Ki Chul Park,et al.  One-pot synthesis of iron oxide―carbon core―shell particles in supercritical water , 2009 .

[263]  M. Mahmoudi,et al.  Cytotoxicity of Uncoated and Polyvinyl Alcohol Coated Superparamagnetic Iron Oxide Nanoparticles , 2009 .

[264]  W. Soboyejo,et al.  LHRH-functionalized superparamagnetic iron oxide nanoparticles for breast cancer targeting and contrast enhancement in MRI , 2009 .

[265]  Chenjie Xu,et al.  Porous hollow Fe(3)O(4) nanoparticles for targeted delivery and controlled release of cisplatin. , 2009, Journal of the American Chemical Society.

[266]  T. Xia,et al.  Understanding biophysicochemical interactions at the nano-bio interface. , 2009, Nature materials.

[267]  G. Hadjipanayis,et al.  Development of heparin-coated magnetic nanoparticles for targeted drug delivery applications , 2009 .

[268]  P. Stadelmann,et al.  Dexamethasone-containing biodegradable superparamagnetic microparticles for intra-articular administration: physicochemical and magnetic properties, in vitro and in vivo drug release. , 2009, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[269]  J. Gooding,et al.  Fabrication and Dispersion of Gold-Shell-Protected Magnetite Nanoparticles : Systematic Control Using Polyethyleneimine , 2009 .

[270]  P. Ajayan,et al.  On the synthesis and magnetic properties of multiwall carbon nanotube–superparamagnetic iron oxide nanoparticle nanocomposites , 2009, Nanotechnology.

[271]  Xiangmin Zhang,et al.  Synthesis of Core/Shell Colloidal Magnetic Zeolite Microspheres for the Immobilization of Trypsin , 2009 .

[272]  Hak Yong Kim,et al.  Gelatin-coated magnetic iron oxide nanoparticles as carrier system: drug loading and in vitro drug release study. , 2009, International journal of pharmaceutics.

[273]  Katayoun Saatchi,et al.  Radiolabeling of biodegradable polymeric microspheres with [99mTc(CO)3]+ and in vivo biodistribution evaluation using MicroSPECT/CT imaging. , 2009, Bioconjugate chemistry.

[274]  Jun Lin,et al.  A magnetic, luminescent and mesoporous core-shell structured composite material as drug carrier. , 2009, Biomaterials.

[275]  Robert Langer,et al.  Impact of nanotechnology on drug delivery. , 2009, ACS nano.

[276]  Sungho Jin,et al.  Magnetic nanoparticles for theragnostics. , 2009, Advanced drug delivery reviews.

[277]  Mohammad Reza Saboktakin,et al.  Synthesis and characterization of superparamagnetic nanoparticles coated with carboxymethyl starch (CMS) for magnetic resonance imaging technique , 2009 .

[278]  Iseult Lynch,et al.  What the cell "sees" in bionanoscience. , 2010, Journal of the American Chemical Society.

[279]  Morteza Mahmoudi,et al.  A new approach for the in vitro identification of the cytotoxicity of superparamagnetic iron oxide nanoparticles. , 2010, Colloids and surfaces. B, Biointerfaces.

[280]  P. Stroeve,et al.  Templated growth of superparamagnetic iron oxide nanoparticles by temperature programming in the presence of poly(vinyl alcohol) , 2010 .

[281]  M. Mahmoudi,et al.  Recent advances in surface engineering of superparamagnetic iron oxide nanoparticles for biomedical applications , 2010 .

[282]  T. Yen,et al.  Magnetic resonance imaging of transplanted mouse islets labeled with chitosan-coated superparamagnetic iron oxide nanoparticles. , 2009, Transplantation proceedings.

[283]  P. Wakeley,et al.  Synthesis , 2013, The Role of Animals in Emerging Viral Diseases.

[284]  S. Majetich,et al.  Magnetic nanoparticles , 2013, Handbook of Magnetism and Magnetic Materials.

[285]  Morteza Mahmoudi,et al.  Protein-Nanoparticle Interactions , 2013 .