Design, analysis, and testing of a motor-driven capsule robot based on a sliding clamper

SUMMARY We propose a motor-driven capsule robot based on a sliding clamper (MCRSC), a device to explore the partially collapsed and winding intestinal tract. The MCRSC is powered by wireless power transmission based on near-field inductive coupling. It comprises a novel locomotion unit, a camera, and a three-dimensional receiving coil, all installed at both ends of the locomotion unit. The novel locomotion unit comprises a linear motion mechanism and a sliding clamper. The former adopts a pair of lead-screw and nut to obtain linear motion, whereas the latter anchors the MCRSC to a specific point of the intestinal tract by expanding its arc-shaped legs. The MCRSC is capable of two-way locomotion, which is activated by alternately executing linear motion and anchoring action. Ex vivo experiments have shown that the MCRSC is able to inspect the colon within a time frame of standard colonoscopy.

[1]  A. Slocum,et al.  Precision Machine Design , 1992 .

[2]  Maria Chiara Carrozza,et al.  A microrobotic system for colonoscopy , 1997, Proceedings of International Conference on Robotics and Automation.

[3]  Joel W. Burdick,et al.  Biomechanical modeling of the small intestine as required for the design and operation of a robotic endoscope , 2000, Proceedings 2000 ICRA. Millennium Conference. IEEE International Conference on Robotics and Automation. Symposia Proceedings (Cat. No.00CH37065).

[4]  P. Swain,et al.  Wireless capsule endoscopy. , 2002, The Israel Medical Association journal : IMAJ.

[5]  Paolo Dario,et al.  Modeling and Experimental Validation of the Locomotion of Endoscopic Robots in the Colon , 2004, Int. J. Robotics Res..

[6]  Angelita Habr-Gama,et al.  Complications and hazards of gastrointestinal endoscopy , 1989, World Journal of Surgery.

[7]  Roustem Miftahof,et al.  The Wave Phenomena in Smooth Muscle Syncytia , 2005, Silico Biol..

[8]  M. Sitti,et al.  Miniature Endoscopic Capsule Robot using Biomimetic Micro-Patterned Adhesives , 2006, The First IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics, 2006. BioRob 2006..

[9]  P. Dario,et al.  Design and Fabrication of a Motor Legged Capsule for the Active Exploration of the Gastrointestinal Tract , 2008, IEEE/ASME Transactions on Mechatronics.

[10]  S. Song,et al.  A novel microactuator for microbiopsy in capsular endoscopes , 2008 .

[11]  P. Dario,et al.  Feasibility proof of a legged locomotion capsule for the GI tract. , 2008, Gastrointestinal endoscopy.

[12]  Sundman Bo.,et al.  エレクトロウェッティングディスプレイの油脱ぬれパターンの観測と光学的意味 | 文献情報 | J-GLOBAL 科学技術総合リンクセンター , 2008 .

[13]  Paolo Dario,et al.  A New Mechanism for Mesoscale Legged Locomotion in Compliant Tubular Environments , 2009, IEEE Transactions on Robotics.

[14]  R. Weersma,et al.  Risk factors for incomplete small-bowel capsule endoscopy. , 2009, Gastrointestinal endoscopy.

[15]  Silvestro Micera,et al.  Hyperelastic Model of Anisotropic Fiber Reinforcements within Intestinal Walls for Applications in Medical Robotics , 2009, Int. J. Robotics Res..

[16]  Paolo Dario,et al.  A reconfigurable modular robotic endoluminal surgical system: vision and preliminary results , 2009, Robotica.

[17]  A Menciassi,et al.  Wireless powering for a self-propelled and steerable endoscopic capsule for stomach inspection. , 2009, Biosensors & bioelectronics.

[18]  P. Dario,et al.  Design, Fabrication, and Testing of a Capsule With Hybrid Locomotion for Gastrointestinal Tract Exploration , 2010, IEEE/ASME Transactions on Mechatronics.

[19]  E. Yoon,et al.  Active locomotion of a paddling-based capsule endoscope in an in vitro and in vivo experiment (with videos). , 2010, Gastrointestinal endoscopy.

[20]  David Zarrouk,et al.  Analysis of Wormlike Robotic Locomotion on Compliant Surfaces , 2011, IEEE Transactions on Biomedical Engineering.

[21]  Elena S. Di Martino,et al.  Biaxial mechanical modeling of the small intestine. , 2011, Journal of the mechanical behavior of biomedical materials.

[22]  Yan Guozheng,et al.  Efficiency optimization of wireless power transmission systems for active capsule endoscopes. , 2011, Physiological measurement.

[23]  P. Dario,et al.  Capsule Endoscopy: From Current Achievements to Open Challenges , 2011, IEEE Reviews in Biomedical Engineering.

[24]  Cheng-Long Chuang,et al.  Magnetic Control System Targeted for Capsule Endoscopic Operations in the Stomach—Design, Fabrication, and in vitro and ex vivo Evaluations , 2012, IEEE Transactions on Biomedical Engineering.

[25]  Hongyi Li,et al.  Modeling of Velocity-dependent Frictional Resistance of a Capsule Robot Inside an Intestine , 2012, Tribology Letters.

[26]  Peng Gao,et al.  Microgroove cushion of robotic endoscope for active locomotion in the gastrointestinal tract , 2012, The international journal of medical robotics + computer assisted surgery : MRCAS.

[27]  J. Schoen,et al.  Small intestine mucosal adhesivity to in vivo capsule robot materials. , 2012, Journal of the mechanical behavior of biomedical materials.

[28]  Metin Sitti,et al.  Design and Rolling Locomotion of a Magnetically Actuated Soft Capsule Endoscope , 2012, IEEE Transactions on Robotics.

[29]  Levin J. Sliker,et al.  Surgical evaluation of a novel tethered robotic capsule endoscope using micro-patterned treads , 2012, Surgical Endoscopy.

[30]  Gursel Alici,et al.  Modeling and Experimental Investigation of Rotational Resistance of a Spiral-Type Robotic Capsule Inside a Real Intestine , 2013, IEEE/ASME Transactions on Mechatronics.

[31]  Timothy G. Constandinou,et al.  Wireless Capsule Endoscope for Targeted Drug Delivery: Mechanics and Design Considerations , 2013, IEEE Transactions on Biomedical Engineering.

[32]  Guozheng Yan,et al.  Wireless powered capsule endoscopy for colon diagnosis and treatment. , 2013, Physiological measurement.

[33]  Tim C. Lueth,et al.  Navigation of a robotic capsule endoscope with a novel ultrasound tracking system , 2013 .

[34]  M. Sitti,et al.  Magnetically Actuated Soft Capsule With the Multimodal Drug Release Function , 2013, IEEE/ASME Transactions on Mechatronics.

[35]  Guozheng Yan,et al.  Design of a wireless anchoring and extending micro robot system for gastrointestinal tract , 2013, The international journal of medical robotics + computer assisted surgery : MRCAS.

[36]  Guozheng Yan,et al.  A wireless capsule robot with spiral legs for human intestine , 2014, The international journal of medical robotics + computer assisted surgery : MRCAS.

[37]  Metin Sitti,et al.  Biopsy using a Magnetic Capsule Endoscope Carrying, Releasing, and Retrieving Untethered Microgrippers , 2014, IEEE Transactions on Biomedical Engineering.

[38]  Mark E Rentschler,et al.  Soft material adhesion characterization for in vivo locomotion of robotic capsule endoscopes: Experimental and modeling results. , 2014, Journal of the mechanical behavior of biomedical materials.