Vancomycin-Resistant Enterococci Outbreak, Germany, and Calculation of Outbreak Start

On the basis of a large outbreak of vancomycin-resistant Enterococcus faecium in a German university hospital, we estimated costs (≈1 million Euros) that could have been avoided by early detection of the imminent outbreak. For this purpose, we demonstrate an easy-to-use statistical method.

[1]  P. Gastmeier,et al.  [Prevention and control of the spread of vancomycin-resistant enterococci: results of a workshop held by the German Society for Hygiene and Microbiology]. , 2007, Der Anaesthesist.

[2]  I. Autenrieth,et al.  Two episodes of vancomycin-resistant Enterococcus faecium outbreaks caused by two genetically different clones in a newborn intensive care unit. , 2004, International journal of hygiene and environmental health.

[3]  C. Wolz,et al.  Discrimination between epidemic and non-epidemic glycopeptide-resistant E. faecium in a post-outbreak situation. , 2007, The Journal of hospital infection.

[4]  Douglas G. Altman,et al.  Practical statistics for medical research , 1990 .

[5]  G. Daeschlein,et al.  Outbreak of Vancomycin-Resistant Enterococci (VRE) in a Hematological Oncology Ward and Hygienic Preventive Measures. A Long-Term Study , 2005, Oncology Research and Treatment.

[6]  R. Anderson,et al.  Vancomycin-resistant enterococci in intensive-care hospital settings: transmission dynamics, persistence, and the impact of infection control programs. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[7]  J. Pearman 2004 Lowbury Lecture: the Western Australian experience with vancomycin-resistant enterococci - from disaster to ongoing control. , 2006, The Journal of hospital infection.

[8]  A. Fahr,et al.  Prävention und Kontrolle der Ausbreitung von Vancomycin-resistenten Enterokokken , 2007, Der Anaesthesist.

[9]  Issues , 2004 .

[10]  U Sagel,et al.  Using mandatory data collection on multiresistant bacteria for internal surveillance in a hospital. , 2004, Methods of information in medicine.

[11]  U. Eigner,et al.  Spread of ampicillin/vancomycin-resistant Enterococcus faecium of the epidemic-virulent clonal complex-17 carrying the genes esp and hyl in German hospitals , 2005, European Journal of Clinical Microbiology and Infectious Diseases.