Drug transfer through mucus.
暂无分享,去创建一个
M D Donovan | D. Flanagan | D R Flanagan | M. Donovan | K. Khanvilkar | K Khanvilkar | Kavita H. Khanvilkar | Maureen D. Donovan | Douglas R. Flanagan
[1] G. Kauffman,et al. Gastric gel mucus thickness: effect of distention, 16,16-dimethyl prostaglandin e2, and carbenoxolone. , 1981, Gastroenterology.
[2] D. Wolf,et al. Human cervical mucus. IV. Viscoelasticity and sperm penetrability during the ovulatory menstrual cycle. , 1978, Fertility and sterility.
[3] A. Silberberg,et al. Structure and function of mucus. , 1978, Ciba Foundation symposium.
[4] Nagai Tsuneji,et al. Powder dosage form of insulin for nasal administration , 1984 .
[5] A. Slomiany,et al. Gastric mucus and the mucosal barrier. , 1987, Digestive diseases.
[6] Werther Jl. The gastric mucosal barrier. , 2000 .
[7] J. M. Creeth,et al. Constituents of mucus and their separation. , 1978, British medical bulletin.
[8] P. Artursson,et al. Diffusion of drugs in native and purified gastrointestinal mucus. , 1997, Journal of pharmaceutical sciences.
[9] J. Robinson,et al. Bioadhesive polymers as platforms for oral controlled drug delivery III: oral delivery of chlorothiazide using a bioadhesive polymer. , 1985, Journal of pharmaceutical sciences.
[10] S. Smedt,et al. The physical properties of biogels and their permeability for macromolecular drugs and colloidal drug carriers. , 2000, Journal of pharmaceutical sciences.
[11] A. Slomiany,et al. Glyceroglucolipids of the mucous barrier of dog stomach. , 1981, Biochimica et biophysica acta.
[12] Patrick J. Sinko,et al. Effect of size, surface charge, and hydrophobicity on the translocation of polystyrene microspheres through gastrointestinal mucin , 1997 .
[13] S. Spicer,et al. Mucin biosynthesis and secretion in the respiratory tract. , 1984, Environmental health perspectives.
[14] D. Winne,et al. Diffusion coefficient in native mucus gel of rat small intestine , 1990, The Journal of pharmacy and pharmacology.
[15] J. Moore,et al. Human ocular mucus. Chemical studies. , 1981, Experimental eye research.
[16] L. Lichtenberger. The hydrophobic barrier properties of gastrointestinal mucus. , 1995, Annual review of physiology.
[17] J. Shelhamer,et al. Effects of arachidonic acid, monohydroxyeicosatetraenoic acid and prostaglandins on the release of mucous glycoproteins from human airways in vitro. , 1981, The Journal of clinical investigation.
[18] S. Davis,et al. Epi‐fluorescence Microscopy and Image Analysis Used to Measure Diffusion Coefficients in Gel Systems , 1992, The Journal of pharmacy and pharmacology.
[19] D. M. Carlson. Structures and immunochemical properties of oligosaccharides isolated from pig submaxillary mucins. , 1968, The Journal of biological chemistry.
[20] N. Ratcliffe,et al. Mucus and related topics. , 1989, Symposia of the Society for Experimental Biology.
[21] H. Ryley,et al. Quantitative immunoelectrophoretic analysis of the plasma proteins in the sol phase of sputum from patients with chronic bronchitis , 1973, Journal of clinical pathology.
[22] Bradley S. Turner,et al. Viscous fingering of HCI through gastric mucin , 1992, Nature.
[23] B. W. Barry,et al. The effect of mucin on the bioavailability of tetracycline from the gastrointestinal tract; in vivo, in vitro correlations , 1974 .
[24] Bradley S. Turner,et al. pH-dependent conformational change of gastric mucin leads to sol-gel transition. , 1999, Biophysical journal.
[25] B. Butler,et al. Role of surface-active phospholipids in gastric cytoprotection. , 1983, Science.
[26] P. Bhat,et al. The limiting role of mucus in drug absorption : drug permeation through mucus solution , 1995 .
[27] K. Moghissi,et al. The Biology of the cervix , 1973 .
[28] A. Macadam. The effect of gastro-intestinal mucus on drug absorption , 1993 .
[29] V. Insler. The evaluation and treatment of cervical mucus diseases leading to infertility. , 1977, Advances in experimental medicine and biology.
[30] N. Peppas,et al. Bioadhesive Tablets Influence of the Testing Medium Composition on Bioadhesion , 1989 .
[31] L. Szentkuti,et al. Light microscopical observations on luminally administered dyes, dextrans, nanospheres and microspheres in the pre-epithelial mucus gel layer of the rat distal colon , 1997 .
[32] D. Aminoff. Blood and tissue antigens. , 1970 .
[33] K. Shephard. Mucus on the epidermis of fish and its influence on drug delivery , 1993 .
[34] N. Peppas,et al. A theory of molecular diffusion in the intestinal mucus , 1984 .
[35] Clarke Sw. Management of mucus hypersecretion. , 1987 .
[36] Widdicombe Jg. Rôle of lipids in airway function. , 1987 .
[37] Nikolaos A. Peppas,et al. Pharmaceutical and Medical Aspects of Bioadhesive Systems for Drug Administration , 1988 .
[38] J. Lafitte,et al. The binding of amikacin to macromolecules from the sputum of patients suffering from respiratory diseases. , 1992, The Journal of antimicrobial chemotherapy.
[39] P. Artursson,et al. The mucus layer as a barrier to drug absorption in monolayers of human intestinal epithelial HT29-H goblet cells , 1993 .
[40] Y. Kim. Glycoprotein alterations in human colonic adenocarcinoma. , 1977, Advances in experimental medicine and biology.
[41] Grübel,et al. Factors affecting solubility and penetration of clarithromycin through gastric mucus , 1998, Alimentary pharmacology & therapeutics.
[42] G. Barbero,et al. Composition of tracheobronchial secretions in cystic fibrosis of the pancreas and bronchiectasis. , 1959, Pediatrics.
[43] E. Neufeld,et al. Complex heterosaccharides of animals. , 1969, Annual review of biochemistry.
[44] M. Oates,et al. Further investigations into the structure of human gastric mucin: the structural configuration of the oligosaccharide chains. , 1974, Carbohydrate research.
[45] J. Dietschy,et al. Derivation of the equations that describe the effects of unstirred water layers on the kinetic parameters of active transport processes in the intestine. , 1977, Journal of theoretical biology.
[46] M. Filipe. Value of histochemical reactions for mucosubstances in the diagnosis of certain pathological conditions of the colon and rectum. , 1969, Gut.
[47] L. Johnson,et al. Physiology of the gastrointestinal tract , 2012 .
[48] J. Pearson,et al. Mucus glycoprotein structure, gel formation and gastrointestinal mucus function. , 1984, Ciba Foundation symposium.
[49] L. Lichtenberger,et al. Luminal surface hydrophobicity of canine gastric mucosa is dependent on a surface mucous gel. , 1990, Gastroenterology.
[50] F. Mi. Mucins in the human gastrointestinal epithelium: a review. , 1979 .
[51] J. Clamp,et al. Proceedings: Changes in human colonic mucus in ulcerative colitis. , 1975, Gut.
[52] D. M. Carlson. Oligosaccharides isolated from pig submaxillary mucin. , 1966, The Journal of biological chemistry.
[53] A. Slomiany,et al. Role of mucus in gastric mucosal protection. , 1991, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
[54] J. Widdicombe. Airway liquid: a barrier to drug diffusion? , 1997, The European respiratory journal.
[55] A. Slomiany,et al. Lipid composition of tracheobronchial secretions from normal individuals and patients with cystic fibrosis. , 1982, Biochimica et biophysica acta.
[56] J. Hadgraft,et al. Absorption of drugs from the human oral cavity , 1991 .
[57] G. Zacchi,et al. Diffusion measurement in gels , 1994 .
[58] H. Ryley,et al. Soluble proteins of bronchopulmonary secretions from patients with cystic fibrosis, asthma, and bronchitis. , 1975, Thorax.
[59] S. Kornfeld,et al. Comparative aspects of glycoprotein structure. , 1976, Annual review of biochemistry.
[60] J. Vonderscher,et al. Contribution to the intestinal absorption of ergot peptide alkaloids , 1980 .
[61] P. Bhat,et al. Drug binding to gastric mucus glycoproteins , 1996 .
[62] J. Vallner. Binding of drugs by albumin and plasma protein. , 1977, Journal of pharmaceutical sciences.
[63] J. Sheehan,et al. Electron microscopy of cervical, gastric and bronchial mucus glycoproteins. , 1986, The Biochemical journal.
[64] Disease,et al. Mucus in Health and Disease , 1977, Advances in Experimental Medicine and Biology.
[65] J. Sheehan,et al. Macromolecular properties and polymeric structure of mucus glycoproteins. , 2008, Ciba Foundation symposium.
[66] M C Meyer,et al. The binding of drugs by plasma proteins. , 1968, Journal of pharmaceutical sciences.
[67] S. Yalkowsky,et al. Mass transport phenomena and models: theoretical concepts. , 1974, Journal of pharmaceutical sciences.
[68] A. Slomiany,et al. Lipolytic activity of Campylobacter pylori: effect of colloidal bismuth subcitrate (De-Nol) , 1989, The American journal of gastroenterology.
[69] S. Mann,et al. Ciba Foundation Symposium , 1997 .
[70] D. Wolf,et al. Human cervical mucus. III. Isolation and characterization of rheologically active mucin. , 1977, Fertility and sterility.
[71] B. Hills. Gastric surfactant and the hydrophobic mucosal barrier. , 1996, Gut.
[72] J. Butler,et al. Conformational structure of respiratory mucus studied by laser correlation spectroscopy. , 1983, Biorheology.
[73] M. Elstein,et al. Effects of the anti-oestrogens, clomiphene and tamoxifen, on the cervical factor in female infertility. , 1984, Ciba Foundation symposium.
[74] Bhaskar Kr,et al. Macromolecular and lipid constituents of bronchial epithelial mucus. , 1989 .
[75] D. Wolf,et al. Effect of mucolytic agents on the rheological properties of tracheal mucus. , 1976, Biochimica et biophysica acta.
[76] D. Ganderton,et al. Drug delivery to the respiratory tract , 1987 .
[77] I M Klotz,et al. PHYSICOCHEMICAL ASPECTS OF DRUG‐PROTEIN INTERACTIONS: A GENERAL PERSPECTIVE , 1973, Annals of the New York Academy of Sciences.
[78] P. Verdugo,et al. Control of mucus hydration as a Donnan equilibrium process , 1981, Nature.
[79] G J Strous,et al. Mucin-type glycoproteins. , 1992, Critical reviews in biochemistry and molecular biology.
[80] Claus-Michael Lehr,et al. An estimate of turnover time of intestinal mucus gel layer in the rat in situ loop , 1991 .
[81] K. Whaley,et al. Antibody diffusion in human cervical mucus. , 1994, Biophysical journal.
[82] P. Kearney,et al. The effects of mucus glycoproteins on the bioavailability of tetracycline. II. Binding , 1987 .
[83] E. Corey,et al. Effects of leukotrienes C4 and D4 on glycoprotein and lysozyme secretion by human bronchial mucosa. , 1983, Prostaglandins.
[84] A. Slomiany,et al. Lipid composition of the gastric mucous barrier in the rat. , 1978, The Journal of biological chemistry.
[85] J. Robinson,et al. Bioadhesive polymers as platforms for oral controlled drug delivery II: synthesis and evaluation of some swelling, water-insoluble bioadhesive polymers. , 1985, Journal of pharmaceutical sciences.
[86] B. Slomiany,et al. Derangements of biosynthesis, production and secretion of mucus in gastrointestinal injury and disease. , 1977, Advances in experimental medicine and biology.
[87] H. Ryley. An immunoelectrophoretic study of the soluble secretory proteins of sputum. , 1972 .
[88] P. Bhat,et al. Drug diffusion through cystic fibrotic mucus: steady-state permeation, rheologic properties, and glycoprotein morphology. , 1996, Journal of pharmaceutical sciences.
[89] K. Bhaskar,et al. Airway mucus: composition and regulation of its secretion by neuropeptides in vitro. , 2008, Ciba Foundation symposium.
[90] S. Kerss,et al. A simple method for measuring thickness of the mucus gel layer adherent to rat, frog and human gastric mucosa: influence of feeding, prostaglandin, N-acetylcysteine and other agents. , 1982, Clinical science.
[91] D. Katz,et al. Factors influencing nonoxynol-9 permeation and bioactivity in cervical mucus. , 1999, Journal of controlled release : official journal of the Controlled Release Society.
[92] H. Kurz,et al. Evaluation of methods to determine protein-binding of drugs. Equilibrium dialysis, ultrafiltration, ultracentrifugation, gel filtration. , 1977, Arzneimittel-Forschung.
[93] J. Lafitte,et al. The complexity of mucins. , 1988, Biochimie.
[94] M. Filipe,et al. Abnormal patterns of mucus secretion in apparently normal mucosa of large intestine with carcinoma , 1974, Cancer.
[95] J. Costerton,et al. Microbial flora of the mouse ileum mucous layer and epithelial surface , 1982, Applied and environmental microbiology.
[96] Y. Aramaki,et al. Binding of antibiotics to rat intestinal mucin , 1986 .
[97] A. Slomiany,et al. The role of covalently bound fatty acids in the degradation of human gastric mucus glycoprotein. , 1984, Archives of biochemistry and biophysics.
[98] M. Basker,et al. The diffusion of beta-lactam antibiotics through mixed gels of cystic fibrosis-derived mucin and Pseudomonas aeruginosa alginate. , 1991, The Journal of antimicrobial chemotherapy.
[99] P. Vadgama,et al. Electrochemical determination of the permeability of porcine mucus to model solute compounds , 1991, The Journal of pharmacy and pharmacology.