OIE Terrestrial Manual 2010 1 C H A P T E R 2 . 7 . 1 4 . 1 SHEEP POX AND GOAT POX 2 SUMMARY

Sheep pox and goat pox are viral diseases of sheep and goats characterised by fever, generalised 4 papules or nodules, vesicles (rarely), internal lesions (particularly in the lungs), and death. Both 5 diseases are caused by strains of capripoxvirus, all of which can infect sheep and goats. Although 6 most of the strains examined cause more severe clinical disease in either sheep or goats, some 7 strains have been isolated that are equally pathogenic in both species. [It has been proposed that the 8 malignant pox diseases of sheep and goats caused by capripoxvirus as well as Kenyan sheep and goat pox, 9 Indian goat dermatitis and north African stone pox of sheep and goats be referred to as capripox.] 10

[1]  S. Babiuk,et al.  Detection of antibodies against capripoxviruses using an inactivated sheeppox virus ELISA. , 2009, Transboundary and emerging diseases.

[2]  R. Kitching,et al.  Clinical and antigenic relationship between isolates of sheep and goat pox viruses , 1985, Tropical Animal Health and Production.

[3]  G. Kärber,et al.  Beitrag zur kollektiven Behandlung pharmakologischer Reihenversuche , 1931, Naunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie.

[4]  M. Hosamani,et al.  Differentiation of Sheep Pox and Goat Poxviruses by Sequence Analysis and PCR-RFLP of P32 Gene , 2004, Virus Genes.

[5]  T. Barrett,et al.  Development of a Dual Recombinant Vaccine To Protect Small Ruminants against Peste-des-Petits-Ruminants Virus and Capripoxvirus Infections , 2003, Journal of Virology.

[6]  H. Heine,et al.  A capripoxvirus detection PCR and antibody ELISA based on the major antigen P32, the homolog of the vaccinia virus H3L gene. , 1999, Journal of immunological methods.

[7]  D. Ireland,et al.  Improved detection of capripoxvirus in biopsy samples by PCR. , 1998, Journal of virological methods.

[8]  V. M. Carn.  An antigen trapping ELISA for the detection of capripoxvirus in tissue culture supernatant and biopsy samples. , 1995, Journal of virological methods.

[9]  R. Kitching,et al.  Western blot analysis of virus-specific antibody responses for capripox and contagious pustular dermatitis viral infections in sheep , 1994, Epidemiology and Infection.

[10]  R. Kitching,et al.  Use of a recombinant antigen in an indirect ELISA for detecting bovine antibody to capripoxvirus. , 1994, Journal of virological methods.

[11]  V. M. Carn.  Control of capripoxvirus infections. , 1993, Vaccine.

[12]  R. Kitching,et al.  The characterization of African strains of capripoxvirus , 1989, Epidemiology and Infection.

[13]  R. Kitching,et al.  Poxvirus genetic recombination during natural virus transmission. , 1989, The Journal of general virology.

[14]  R. Kitching,et al.  A single vaccine for the control of capripox infection in sheep and goats. , 1987, Research in veterinary science.

[15]  R. Kitching,et al.  Comparison of the external dimensions of capripoxvirus isolates. , 1986, Research in veterinary science.

[16]  R. Kitching,et al.  Genomic relationship between capripoxviruses. , 1986, Virus research.

[17]  F. Davies,et al.  The alterations in pathogenicity and immunogenicity of a Kenya sheep and goat pox virus on serial passage in bovine foetal muscle cell cultures. , 1985, Journal of comparative pathology.

[18]  P. Kitching.  Progress towards sheep and goat pox vaccines. , 1983, Vaccine.

[19]  F. Davies,et al.  The antibody response in sheep infected with a Kenyan sheep and goat pox virus. , 1978, Journal of comparative pathology.